BRCA1 regulation of epidermal growth factor receptor (EGFR) expression in human breast cancer cells involves microRNA-146a and is critical for its tumor suppressor function

MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review

(2012) Marilena V. Iorio et al.   EMBO Molecular Medicine

BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex

(2012) Shinji Kawai et al.   JOURNAL OF CELL BIOLOGY

Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer

(2012) Stefan Uhlmann et al.   Molecular Systems Biology

BRCA1 and MicroRNAs: Emerging networks and potential therapeutic targets

(2012) Suhwan Chang et al.   MOLECULES AND CELLS

Increased Risk of Breast Cancer Associated with CC Genotype of Has-miR-146a Rs2910164 Polymorphism in Europeans

(2012) Hai Lian et al.   PLoS One

BRCA1 – Conductor of the Breast Stem Cell Orchestra: The Role of BRCA1 in Mammary Gland Development and Identification of Cell of Origin of BRCA1 Mutant Breast Cancer

(2012) Niamh E. Buckley et al.   Stem Cell Reviews and Reports

Mechanisms of BRCA1 Tumor Suppression: Figure 1.

(2012) Daniel P. Silver et al.   Cancer Discovery

Integration of BRCA1-mediated miRNA and mRNA profiles reveals microRNA regulation of TRAF2 and NFκB pathway

(2011) Miljana Tanic et al.   BREAST CANCER RESEARCH AND TREATMENT

Down-regulation ofBRCA1expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers

(2011) Amandine I. Garcia et al.   EMBO Molecular Medicine

miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice

(2011) Mark P. Boldin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inherited Mutations in Breast Cancer Genes—Risk and Response

(2011) Andrew Y. Shuen et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

MicroRNA-146a Inhibits Glioma Development by Targeting Notch1

(2011) J. Mei et al.   MOLECULAR AND CELLULAR BIOLOGY

Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155

(2011) Suhwan Chang et al.   NATURE MEDICINE

NF- B dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies

(2011) J. L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castration-resistant prostate cancer

(2011) Bin Xu et al.   PROSTATE

Epidermal growth factor receptor expression in breast cancer association with biologic phenotype and clinical outcomes

(2010) Mothaffar F. Rimawi et al.   CANCER

miR-146a Suppresses Invasion of Pancreatic Cancer Cells

(2010) Y. Li et al.   CANCER RESEARCH

BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

(2010) Gemma Molyneux et al.   Cell Stem Cell

BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer

(2009) Julia J. Gorski et al.   BREAST CANCER RESEARCH AND TREATMENT

Breast Cancer Metastasis Suppressor 1 Up-regulates miR-146, Which Suppresses Breast Cancer Metastasis

(2009) Douglas R. Hurst et al.   CANCER RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

ErbB receptors and signaling pathways in cancer

(2009) Nancy E Hynes et al.   CURRENT OPINION IN CELL BIOLOGY

Amphiregulin mediates self-renewal in an immortal mammary epithelial cell line with stem cell characteristics

(2009) Brian W. Booth et al.   EXPERIMENTAL CELL RESEARCH

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

(2009) Elgene Lim et al.   NATURE MEDICINE

BRCA1 and its toolbox for the maintenance of genome integrity

(2009) Michael S.Y. Huen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Frequently increased epidermal growth factor receptor (EGFR) copy numbers and decreased BRCA1 mRNA expression in Japanese triple-negative breast cancers

(2008) Tatsuya Toyama et al.   BMC CANCER

Invasive ductal carcinoma of the breast with the “triple-negative” phenotype: prognostic implications of EGFR immunoreactivity

(2008) Giuseppe Viale et al.   BREAST CANCER RESEARCH AND TREATMENT

Expression of epidermal growth factor receptor in relation to BRCA1 status, basal-like markers and prognosis in breast cancer

(2008) J B Arnes et al.   JOURNAL OF CLINICAL PATHOLOGY

Expression of microRNA-146 suppresses NF-κB activity with reduction of metastatic potential in breast cancer cells

(2008) D Bhaumik et al.   ONCOGENE