BRCA1 – Conductor of the Breast Stem Cell Orchestra: The Role of BRCA1 in Mammary Gland Development and Identification of Cell of Origin of BRCA1 Mutant Breast Cancer

The  Np63 Proteins Are Key Allies of BRCA1 in the Prevention of Basal-Like Breast Cancer

(2011) N. E. Buckley et al.   CANCER RESEARCH

Genetic Predisposition Directs Breast Cancer Phenotype by Dictating Progenitor Cell Fate

(2011) Theresa A. Proia et al.   Cell Stem Cell

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Cells of origin in cancer

(2011) Jane E. Visvader   NATURE

Erratum: Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155

(2011) Suhwan Chang et al.   NATURE MEDICINE

BRCA1 and GATA3 corepress FOXC1 to inhibit the pathogenesis of basal-like breast cancers

(2011) D Tkocz et al.   ONCOGENE

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

(2011) C. L. Chaffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BRCA1 Tumor Suppression Depends on BRCT Phosphoprotein Binding, But Not Its E3 Ligase Activity

(2011) R. Shakya et al.   SCIENCE

Altered Gene Expression in Morphologically Normal Epithelial Cells from Heterozygous Carriers of BRCA1 or BRCA2 Mutations

(2010) A. Bellacosa et al.   Cancer Prevention Research

Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

(2010) Ö Yalcin-Ozuysal et al.   CELL DEATH AND DIFFERENTIATION

BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

(2010) Gemma Molyneux et al.   Cell Stem Cell

Cancer stem cells: Back to Darwin?

(2010) Mel Greaves   SEMINARS IN CANCER BIOLOGY

Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics

(2009) B. T. Hennessy et al.   CANCER RESEARCH

The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells

(2009) Angelo Cicalese et al.   CELL

Mammary development meets cancer genomics

(2009) Aleix Prat et al.   NATURE MEDICINE

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

(2009) Elgene Lim et al.   NATURE MEDICINE

Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression

(2008) Samuel Godar et al.   CELL

Transcriptome Analysis of the Normal Human Mammary Cell Commitment and Differentiation Process

(2008) Afshin Raouf et al.   Cell Stem Cell

Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments

(2008) Mark A. LaBarge et al.   Integrative Biology

β1 Integrin deletion from the basal compartment of the mammary epithelium affects stem cells

(2008) Ilaria Taddei et al.   NATURE CELL BIOLOGY

BRCA1 regulates human mammary stem/progenitor cell fate

(2008) S. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA