Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase of miR-210 in lung adenocarcinoma cells and their exosomes

Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210

(2014) Haopeng Wang et al.   NATURE IMMUNOLOGY

Cytokine functions of TIMP-1

(2013) Christian Ries   CELLULAR AND MOLECULAR LIFE SCIENCES

WSS25 inhibits Dicer, downregulating microRNA-210, which targets Ephrin-A3, to suppress human microvascular endothelial cell (HMEC-1) tube formation

(2013) Fei Xiao et al.   GLYCOBIOLOGY

The perivascular niche regulates breast tumour dormancy

(2013) Cyrus M. Ghajar et al.   NATURE CELL BIOLOGY

Exosomal Signaling during Hypoxia Mediates Microvascular Endothelial Cell Migration and Vasculogenesis

(2013) Carlos Salomon et al.   PLoS One

Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development

(2013) P. Kucharzewska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteolytic factors in exosomes

(2013) Masayuki Shimoda et al.   PROTEOMICS

In papillary thyroid carcinoma, TIMP-1 expression correlates with BRAF V600E mutation status and together with hypoxia-related proteins predicts aggressive behavior

(2013) Marius I. Ilie et al.   VIRCHOWS ARCHIV

MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines

(2013) S Grosso et al.   Cell Death & Disease

Hypoxic enhancement of exosome release by breast cancer cells

(2012) Hamish W King et al.   BMC CANCER

Hypoxia-Inducible miR-210 Regulates the Susceptibility of Tumor Cells to Lysis by Cytotoxic T Cells

(2012) M. Z. Noman et al.   CANCER RESEARCH

Up-regulation of miR-210 by vascular endothelial growth factor inex vivoexpanded CD34+ cells enhances cell-mediated angiogenesis

(2012) Mohamad Amer Alaiti et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model

(2012) Yifeng Xia et al.   NATURE CELL BIOLOGY

TIMP-1 Induces an EMT-Like Phenotypic Conversion in MDCK Cells Independent of Its MMP-Inhibitory Domain

(2012) Young Suk Jung et al.   PLoS One

On the Pro-Metastatic Stress Response to Cancer Therapies: Evidence for a Positive Co-Operation between TIMP-1, HIF-1α, and miR-210

(2012) Haissi Cui et al.   Frontiers in Pharmacology

Targeting NF-κB and HIF-1 Pathways for the Treatment of Cancer: Part II

(2011) Jacek Wilczynski et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Hypoxia-inducible MicroRNA-210 augments the metastatic potential of tumor cells by targeting vacuole membrane protein 1 in hepatocellular carcinoma

(2011) Qiao Ying et al.   HEPATOLOGY

miR-210: The Master Hypoxamir

(2011) YUK C. CHAN et al.   MICROCIRCULATION

A Hypoxia-Induced Positive Feedback Loop Promotes Hypoxia-Inducible Factor 1  Stability through miR-210 Suppression of Glycerol-3-Phosphate Dehydrogenase 1-Like

(2011) T. J. Kelly et al.   MOLECULAR AND CELLULAR BIOLOGY

Tissue inhibitor of metalloproteinase-1 promotes NIH3T3 fibroblast proliferation by activating p-Akt and cell cycle progression

(2011) Yang Lu et al.   MOLECULES AND CELLS

Full-Length L1CAM and Not Its Δ2Δ27 Splice Variant Promotes Metastasis through Induction of Gelatinase Expression

(2011) Stephanie Hauser et al.   PLoS One

Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses

(2011) Angélique Bobrie et al.   TRAFFIC

Tissue inhibitors of metalloproteinases

(2011) Gillian Murphy   GENOME BIOLOGY

The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

(2010) Keith Brew et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer

(2010) Antonis Giannakakis et al.   CANCER BIOLOGY & THERAPY

MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT

(2010) Zhan Zhang et al.   CELL CYCLE

MicroRNA-210: A unique and pleiotropic hypoxamir

(2010) Stephen Y. Chan et al.   CELL CYCLE

miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity

(2010) M-P Puisségur et al.   CELL DEATH AND DIFFERENTIATION

Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by hypoxia-inducible factor-1α

(2010) Florian Schelter et al.   CLINICAL & EXPERIMENTAL METASTASIS

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

MicroRNA-210 Regulates Cancer Cell Proliferation through Targeting Fibroblast Growth Factor Receptor-like 1 (FGFRL1)

(2010) Soken Tsuchiya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxic Tumor Cell Modulates Its Microenvironment to Enhance Angiogenic and Metastatic Potential by Secretion of Proteins and Exosomes

(2010) Jung Eun Park et al.   MOLECULAR & CELLULAR PROTEOMICS

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

In vitro angiogenesis: endothelial cell tube formation on gelled basement membrane extract

(2010) Irina Arnaoutova et al.   Nature Protocols

Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line

(2010) Keiichi Ohshima et al.   PLoS One

MiR-210 – micromanager of the hypoxia pathway

(2010) Xin Huang et al.   TRENDS IN MOLECULAR MEDICINE

Avoiding spam in the proteolytic internet: Future strategies for anti-metastatic MMP inhibition

(2009) Achim Krüger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

MicroRNA Regulation of DNA Repair Gene Expression in Hypoxic Stress

(2009) M. E. Crosby et al.   CANCER RESEARCH

MicroRNA-210 Controls Mitochondrial Metabolism during Hypoxia by Repressing the Iron-Sulfur Cluster Assembly Proteins ISCU1/2

(2009) Stephen Y. Chan et al.   Cell Metabolism

Exosomal MicroRNA: A Diagnostic Marker for Lung Cancer

(2009) Guilherme Rabinowits et al.   Clinical Lung Cancer

HIF-1: upstream and downstream of cancer metabolism

(2009) Gregg L Semenza   CURRENT OPINION IN GENETICS & DEVELOPMENT

Ischemic Preconditioning Augments Survival of Stem Cells via miR-210 Expression by Targeting Caspase-8-associated Protein 2

(2009) Ha Won Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation

(2009) Xin Huang et al.   MOLECULAR CELL

Fibroblasts potentiate blood vessel formation partially through secreted factor TIMP-1

(2008) Hua Liu et al.   ANGIOGENESIS

The Role of Tissue Inhibitors of Metalloproteinases in Tumorigenesis and Metastasis

(2008) William Cruz-Munoz et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

MicroRNA-210 Modulates Endothelial Cell Response to Hypoxia and Inhibits the Receptor Tyrosine Kinase Ligand Ephrin-A3

(2008) Pasquale Fasanaro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

Tissue Inhibitors of Metalloproteinases in Cell Signaling: Metalloproteinase-Independent Biological Activities

(2008) W. G. Stetler-Stevenson   Science Signaling