Proteolytic factors in exosomes

Tetraspanins Regulate ADAM10-Mediated Cleavage of TNF-  and Epidermal Growth Factor

(2014) C. Arduise et al.   JOURNAL OF IMMUNOLOGY

Exosomes from Bronchoalveolar Fluid of Tolerized Mice Prevent Allergic Reaction

(2014) N. Prado et al.   JOURNAL OF IMMUNOLOGY

Exosome release of ADAM15 and the functional implications of human macrophage-derived ADAM15 exosomes

(2012) Hee Doo Lee et al.   FASEB JOURNAL

Metalloprotease (ADAM12-S) as a Predictor of Preeclampsia: Correlation with Severity, Maternal Complications, Fetal Outcome, and Doppler Parameters

(2012) Walid El-Sherbiny et al.   HYPERTENSION IN PREGNANCY

Notch Activation by the Metalloproteinase ADAM17 Regulates Myeloproliferation and Atopic Barrier Immunity by Suppressing Epithelial Cytokine Synthesis

(2012) Aditya Murthy et al.   IMMUNITY

Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity

(2012) Alessandra Lo Cicero et al.   MATRIX BIOLOGY

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

(2012) Bow J. Tauro et al.   METHODS

Exosomes as Biomarker Enriched Microvesicles: Characterization of Exosomal Proteins Derived from a Panel of Prostate Cell Lines with Distinct AR Phenotypes

(2012) Elham Hosseini-Beheshti et al.   MOLECULAR & CELLULAR PROTEOMICS

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Medulloblastoma Exosome Proteomics Yield Functional Roles for Extracellular Vesicles

(2012) Laura M. Epple et al.   PLoS One

The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9

(2011) Maria Dolores Gutiérrez-López et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Roles of Tumor-Derived Exosomes in Cancer Pathogenesis

(2011) Chenjie Yang et al.   Clinical & Developmental Immunology

Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage

(2011) Anne-Kathleen Rupp et al.   GYNECOLOGIC ONCOLOGY

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Protective roles of matrix metalloproteinases: From mouse models to human cancer

(2010) Carlos López-Otín et al.   CELL CYCLE

CD23 Sheddase A Disintegrin and Metalloproteinase 10 (ADAM10) Is Also Required for CD23 Sorting into B Cell-derived Exosomes

(2010) Joel A. Mathews et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non-neoplastic diseases

(2010) Takayuki Shiomi et al.   PATHOLOGY INTERNATIONAL

Advances in membranous vesicle and exosome proteomics improving biological understanding and biomarker discovery

(2010) Francesca Raimondo et al.   PROTEOMICS

COP9-Associated CSN5 Regulates Exosomal Protein Deubiquitination and Sorting

(2009) Yuelong Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes

(2009) Sascha Keller et al.   CANCER LETTERS

ADAMTS Metalloproteases Generate Active Versican Fragments that Regulate Interdigital Web Regression

(2009) Daniel R. McCulloch et al.   DEVELOPMENTAL CELL

Tetraspanin12 regulates ADAM10-dependent cleavage of amyloid precursor protein

(2009) Daosong Xu et al.   FASEB JOURNAL

Conditional Inactivation of TACE by a Sox9 Promoter Leads to Osteoporosis and Increased Granulopoiesis via Dysregulation of IL-17 and G-CSF

(2009) K. Horiuchi et al.   JOURNAL OF IMMUNOLOGY

Proteomic Analysis of Human Parotid Gland Exosomes by Multidimensional Protein Identification Technology (MudPIT)

(2009) Mireya Gonzalez-Begne et al.   JOURNAL OF PROTEOME RESEARCH

Senescence-Associated Exosome Release from Human Prostate Cancer Cells

(2008) B. D. Lehmann et al.   CANCER RESEARCH

Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice

(2008) A Lespagnol et al.   CELL DEATH AND DIFFERENTIATION

Inhibition of γ-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes

(2008) Robyn A. Sharples et al.   FASEB JOURNAL

MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer

(2008) Douglas D. Taylor et al.   GYNECOLOGIC ONCOLOGY

Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes

(2008) Juha Hakulinen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Heat shock protein-containing exosomes in mid-trimester amniotic fluids

(2008) Alexzander Asea et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

(2008) P. A. Gonzales et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

(2008) Khalid Al-Nedawi et al.   NATURE CELL BIOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

Clipping, shedding and RIPping keep immunity on cue

(2008) Gillian Murphy et al.   TRENDS IN IMMUNOLOGY