MCT-1 expression and PTEN deficiency synergistically promote neoplastic multinucleation through the Src/p190B signaling activation

Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity

(2015) Hung-Ju Shih et al.   Oncotarget

Function of oncogenes in cancer development: a changing paradigm

(2013) Carolina Vicente-Dueñas et al.   EMBO JOURNAL

The cancer biology of whole-chromosome instability

(2013) P H G Duijf et al.   ONCOGENE

Akt and c-Myc Induce Stem-Cell Markers in Mature Primary p53−/− Astrocytes and Render These Cells Gliomagenic in the Brain of Immunocompetent Mice

(2013) Josefine Radke et al.   PLoS One

The involvement of MCT-1 oncoprotein in inducing mitotic catastrophe and nuclear abnormalities

(2012) Hung-Ju Shih et al.   CELL CYCLE

P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells

(2012) Melissa Hwang et al.   Cancers

The antagonism between MCT-1 and p53 affects the tumorigenic outcomes

(2011) Ravi Kasiappan et al.   Molecular Cancer

Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways

(2011) Siyuan Zhang et al.   NATURE MEDICINE

A mouse model of heterogeneous, c-MYC-initiated prostate cancer with loss of Pten and p53

(2011) J Kim et al.   ONCOGENE

Mitotic Down-regulation of p190RhoGAP Is Required for the Successful Completion of Cytokinesis

(2010) Sergio A. Sánchez Manchinelly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subtle variations in Pten dose determine cancer susceptibility

(2010) Andrea Alimonti et al.   NATURE GENETICS

p190RhoGAP negatively regulates Rho activity at the cleavage furrow of mitotic cells

(2009) Ling Su et al.   EXPERIMENTAL CELL RESEARCH

Loss of p53 and MCT-1 Overexpression Synergistically Promote Chromosome Instability and Tumorigenicity

(2009) R. Kasiappan et al.   MOLECULAR CANCER RESEARCH

The nuclear affairs of PTEN

(2008) S. M. Planchon et al.   JOURNAL OF CELL SCIENCE

PTEN Nuclear Localization Is Regulated by Oxidative Stress and Mediates p53-Dependent Tumor Suppression

(2008) C.-J. Chang et al.   MOLECULAR AND CELLULAR BIOLOGY

p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

(2008) Hongwu Zheng et al.   NATURE

PTEN deficiency accelerates tumour progression in a mouse model of thyroid cancer

(2008) C J Guigon et al.   ONCOGENE

PTEN: a new guardian of the genome

(2008) Y Yin et al.   ONCOGENE