Whole chromosome instability resulting from the synergistic effects of pRB and p53 inactivation

Chromosome instability and deregulated proliferation: an unavoidable duo

(2012) Courtney H. Coschi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Losing balance: the origin and impact of aneuploidy in cancer

(2012) Andrew J Holland et al.   EMBO REPORTS

Chromosomal instability and aneuploidy in cancer: from yeast to man

(2012) Sarah J Pfau et al.   EMBO REPORTS

Cooperation between Rb and Arf in suppressing mouse retinoblastoma

(2012) Karina Conkrite et al.   JOURNAL OF CLINICAL INVESTIGATION

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

(2012) Jinghui Zhang et al.   NATURE

The RB family is required for the self-renewal and survival of human embryonic stem cells

(2012) Jamie F. Conklin et al.   Nature Communications

Mad2 Is a Critical Mediator of the Chromosome Instability Observed upon Rb and p53 Pathway Inhibition

(2011) Juan-Manuel Schvartzman et al.   CANCER CELL

Relationship of Extreme Chromosomal Instability with Long-term Survival in a Retrospective Analysis of Primary Breast Cancer

(2011) R. Roylance et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Somatic mutation ofSTAG2, an aneuploidy-related gene, is rare in acute leukemias

(2011) Nak Gyun Chung et al.   LEUKEMIA & LYMPHOMA

Chromosome Segregation Errors as a Cause of DNA Damage and Structural Chromosome Aberrations

(2011) A. Janssen et al.   SCIENCE

pRB, a tumor suppressor with a stabilizing presence

(2011) Amity L. Manning et al.   TRENDS IN CELL BIOLOGY

Conserved RB functions in development and tumor suppression

(2011) Gabriel M. Gordon et al.   Protein & Cell

Chromosomal instability: A composite phenotype that influences sensitivity to chemotherapy

(2010) Sarah E. McClelland et al.   CELL CYCLE

RB-pathway disruption in breast cancer

(2010) Adam Ertel et al.   CELL CYCLE

CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity

(2010) Amity L Manning et al.   EMBO JOURNAL

Loss of pRB causes centromere dysfunction and chromosomal instability

(2010) A. L. Manning et al.   GENES & DEVELOPMENT

Proliferation of aneuploid human cells is limited by a p53-dependent mechanism

(2010) Sarah L. Thompson et al.   JOURNAL OF CELL BIOLOGY

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

(2010) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retinoblastoma Has Properties of a Cone Precursor Tumor and Depends Upon Cone-Specific MDM2 Signaling

(2009) Xiaoliang L. Xu et al.   CELL

Chromosomal instability correlates with poor outcome in patients with myelodysplastic syndromes irrespectively of the cytogenetic risk group

(2009) Christoph E. Heilig et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Chromosomal instability determines taxane response

(2009) C. Swanton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of RB1 induces non-proliferative retinoma: increasing genomic instability correlates with progression to retinoblastoma

(2008) Helen Dimaras et al.   HUMAN MOLECULAR GENETICS

Examining the link between chromosomal instability and aneuploidy in human cells

(2008) Sarah L. Thompson et al.   JOURNAL OF CELL BIOLOGY

Chromosomal instability is a risk factor for poor prognosis of adenocarcinoma of the lung: Fluorescence in situ hybridization analysis of paraffin-embedded tissue from Korean patients

(2008) Chang-Min Choi et al.   LUNG CANCER

Conserved functions of the pRB and E2F families

(2008) Sander van den Heuvel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY