Inhibition of monocarboxylate transporter-4 depletes stem-like glioblastoma cells and inhibits HIF transcriptional response in a lactate-independent manner

Metabolic Targeting of Lactate Efflux by Malignant Glioma Inhibits Invasiveness and Induces Necrosis: An In Vivo Study

(2015) Chaim B Colen et al.   NEOPLASIA

HIF-1α up-regulates NDRG1 expression through binding to NDRG1 promoter, leading to proliferation of lung cancer A549 cells

(2013) Qiang Wang et al.   MOLECULAR BIOLOGY REPORTS

FoxM1 and Wnt/ -Catenin Signaling in Glioma Stem Cells

(2012) A. Gong et al.   CANCER RESEARCH

Wnt/beta-Catenin Signaling in Glioma

(2012) Kailiang Zhang et al.   Journal of Neuroimmune Pharmacology

Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets

(2012) Vera Miranda-Gonçalves et al.   NEURO-ONCOLOGY

Alterations of monocarboxylate transporter densities during hypoxia in brain and breast tumour cells

(2012) Chang Cheng et al.   CELLULAR ONCOLOGY

Notch signaling contributes to the maintenance of both normal neural stem cells and patient-derived glioma stem cells

(2011) Yi-Yang Hu et al.   BMC CANCER

Culture of human mesenchymal stem cells at low oxygen tension improves growth and genetic stability by activating glycolysis

(2011) J C Estrada et al.   CELL DEATH AND DIFFERENTIATION

Gene Expression Profiles and Metabolic Changes in Embryonic Neural Progenitor Cells Under Low Oxygen

(2011) Ling-Ling Zhu et al.   Cellular Reprogramming

In vivo pH in metabolic-defective Ras-transformed fibroblast tumors: Key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH

(2011) Johanna Chiche et al.   INTERNATIONAL JOURNAL OF CANCER

Metabolic Alterations in Highly Tumorigenic Glioblastoma Cells

(2011) Yunfei Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-canonical HIF-2α function drives autonomous breast cancer cell growth via an AREG–EGFR/ErbB4 autocrine loop

(2011) D P Stiehl et al.   ONCOGENE

CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors

(2011) R. Le Floch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia Increases the Expression of Stem-Cell Markers and Promotes Clonogenicity in Glioblastoma Neurospheres

(2010) Eli E. Bar et al.   AMERICAN JOURNAL OF PATHOLOGY

STC2: A Predictive Marker for Lymph Node Metastasis in Esophageal Squamous-Cell Carcinoma

(2010) Yoshiaki Kita et al.   ANNALS OF SURGICAL ONCOLOGY

A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2α

(2010) Sascha Seidel et al.   BRAIN

Glioblastoma, Cancer Stem Cells and Hypoxia

(2010) Eli E. Bar   BRAIN PATHOLOGY

Hypoxia inducible factors in cancer stem cells

(2010) J M Heddleston et al.   BRITISH JOURNAL OF CANCER

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

(2010) John M. Heddleston et al.   CELL CYCLE

Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

(2009) Zhizhong Li et al.   CANCER CELL

Quantitative Metrics of Net Proliferation and Invasion Link Biological Aggressiveness Assessed by MRI with Hypoxia Assessed by FMISO-PET in Newly Diagnosed Glioblastomas

(2009) M. D. Szeto et al.   CANCER RESEARCH

miR-124 is frequently down-regulated in medulloblastoma and is a negative regulator of SLC16A1

(2009) Kay Ka Wai Li et al.   HUMAN PATHOLOGY

The Lysyl Oxidases LOX and LOXL2 Are Necessary and Sufficient to Repress E-cadherin in Hypoxia

(2009) Ruth Schietke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α

(2009) A Soeda et al.   ONCOGENE

Hypoxia and HIF1α Repress the Differentiative Effects of BMPs in High-Grade Glioma

(2008) Francesca Pistollato et al.   STEM CELLS

Identification of Oxygen-Sensitive Transcriptional Programs in Human Embryonic Stem Cells

(2008) Suzanne D. Westfall et al.   STEM CELLS AND DEVELOPMENT