Mcm2 deficiency results in short deletions allowing high resolution identification of genes contributing to lymphoblastic lymphoma

E47 Controls the Developmental Integrity and Cell Cycle Quiescence of Multipotential Hematopoietic Progenitors

(2014) Q. Yang et al.   JOURNAL OF IMMUNOLOGY

How dormant origins promote complete genome replication

(2011) J. Julian Blow et al.   TRENDS IN BIOCHEMICAL SCIENCES

Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL

(2010) R. Jeannet et al.   BLOOD

Disruption of zebrafish cyclin G-associated kinase (GAK) function impairs the expression of Notch-dependent genes during neurogenesis and causes defects in neuronal development

(2010) Ting Bai et al.   BMC DEVELOPMENTAL BIOLOGY

Coexistence of alternative MLL–SEPT9 fusion transcripts in an acute myeloid leukemia with t(11;17)(q23;q25)

(2010) Joana Santos et al.   CANCER GENETICS AND CYTOGENETICS

The Mi-2/NuRD complex: A critical epigenetic regulator of hematopoietic development, differentiation and cancer

(2010) Julita Ramírez et al.   Epigenetics

Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories

(2010) Xin Quan Ge et al.   JOURNAL OF CELL BIOLOGY

Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1

(2010) A Tefferi   LEUKEMIA

Genomic profiling of high-risk acute lymphoblastic leukemia

(2010) J R Collins-Underwood et al.   LEUKEMIA

The TLX1 oncogene drives aneuploidy in T cell transformation

(2010) Kim De Keersmaecker et al.   NATURE MEDICINE

DNMT3AMutations in Acute Myeloid Leukemia

(2010) Timothy J. Ley et al.   NEW ENGLAND JOURNAL OF MEDICINE

DNA damage response and tumorigenesis in Mcm2-deficient mice

(2010) D Kunnev et al.   ONCOGENE

Reducing MCM levels in human primary T cells during the G0→G1 transition causes genomic instability during the first cell cycle

(2010) S J Orr et al.   ONCOGENE

Incremental Genetic Perturbations to MCM2-7 Expression and Subcellular Distribution Reveal Exquisite Sensitivity of Mice to DNA Replication Stress

(2010) Chen-Hua Chuang et al.   PLoS Genetics

High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-  and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response

(2009) M. Remke et al.   BLOOD

RAD6-Mediated Transcription-Coupled H2B Ubiquitylation Directly Stimulates H3K4 Methylation in Human Cells

(2009) Jaehoon Kim et al.   CELL

Uncovering Early Response of Gene Regulatory Networks in ESCs by Systematic Induction of Transcription Factors

(2009) Akira Nishiyama et al.   Cell Stem Cell

New insights to the MLL recombinome of acute leukemias

(2009) C Meyer et al.   LEUKEMIA

Identification and characterization of novel human tissue-specific RFX transcription factors

(2008) Syed Aftab et al.   BMC EVOLUTIONARY BIOLOGY

Regulation of T-cell responses by PTEN

(2008) Jodi L. Buckler et al.   IMMUNOLOGICAL REVIEWS

Vav1: A hematopoietic signal transduction molecule involved in human malignancies

(2008) Shulamit Katzav   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication

(2008) Arkaitz Ibarra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA