Selective Biocatalytic Acylation Studies on 5′-O-(4,4′-Dimethoxytrityl)-2′,3′-Secouridine: An Efficient Synthesis of UNA Monomer

Biocatalytic Deacylation Studies on Tetra-O-acyl-β-d-xylofuranosyl Nucleosides: Synthesis ofxylo-LNA Monomers

(2011) Sunil K. Singh et al.   JOURNAL OF ORGANIC CHEMISTRY

Unlocked nucleic acid – an RNA modification with broad potential

(2011) Anna Pasternak et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Biocatalytic Separation ofN-7/N-9 Guanine Nucleosides

(2010) Sunil K. Singh et al.   JOURNAL OF ORGANIC CHEMISTRY

Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo

(2010) Maria B. Laursen et al.   Molecular BioSystems

Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer

(2010) Anna Pasternak et al.   NUCLEIC ACIDS RESEARCH

A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

(2010) Jesper B. Bramsen et al.   NUCLEIC ACIDS RESEARCH

UNA (unlocked nucleic acid): A flexible RNA mimic that allows engineering of nucleic acid duplex stability

(2009) Niels Langkjær et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Exploring the Water-Soluble Phosphine Ligand as the Environmentally Friendly Stabilizer for Electroless Nickel Plating

(2009) Ke Wang et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Filling the gap in LNA antisense oligo gapmers: the effects of unlocked nucleic acid (UNA) and 4′-C-hydroxymethyl-DNA modifications on RNase H recruitment and efficacy of an LNA gapmer

(2009) Kees Fluiter et al.   Molecular BioSystems

Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5′-terminal phosphorylation both in vitro and in vivo

(2009) Denise M. Kenski et al.   NUCLEIC ACIDS RESEARCH

A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

(2009) Jesper B. Bramsen et al.   NUCLEIC ACIDS RESEARCH

Efficient and Selective Enzymatic Acylation Reaction: Separation of Furanosyl and Pyranosyl Nucleosides

(2008) Jyotirmoy Maity et al.   JOURNAL OF ORGANIC CHEMISTRY