Functional redundancy between the transcriptional activation domains of E2A is mediated by binding to the KIX domain of CBP/p300

Differential Roles for the E2A Activation Domains in B Lymphocytes and Macrophages

(2014) S. Bhalla et al.   JOURNAL OF IMMUNOLOGY

Allosteric Communication in the KIX Domain Proceeds through Dynamic Repacking of the Hydrophobic Core

(2013) Sven Brüschweiler et al.   ACS Chemical Biology

E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment

(2013) W. Xu et al.   BLOOD

Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition

(2013) Feng Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

E2A proteins enhance the histone acetyltransferase activity of the transcriptional co-activators CBP and p300

(2012) Brandy D. Hyndman et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Structural basis of CBP/p300 recruitment in leukemia induction by E2A-PBX1

(2012) C. M. Denis et al.   BLOOD

HEB in the Spotlight: Transcriptional Regulation of T-Cell Specification, Commitment, and Developmental Plasticity

(2012) Marsela Braunstein et al.   Clinical & Developmental Immunology

Biochemical and Phosphoproteomic Analysis of the Helix-Loop-Helix Protein E47

(2012) R. Teachenor et al.   MOLECULAR AND CELLULAR BIOLOGY

Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment

(2012) F. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of T Cell Development and Transformation

(2011) Ute Koch et al.   Annual Review of Cell and Developmental Biology

Mapping acetylation sites in E2A identifies a conserved lysine residue in activation domain 1 that promotes CBP/p300 recruitment and transcriptional activation

(2011) Brandy D. Hyndman et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Transcriptional and epigenetic regulation of B cell development

(2011) Patricia Santos et al.   IMMUNOLOGIC RESEARCH

Transcriptional control of T-cell development

(2011) T. Naito et al.   INTERNATIONAL IMMUNOLOGY

Functional Diversity of Human Basic Helix-Loop-Helix Transcription Factor TCF4 Isoforms Generated by Alternative 5′ Exon Usage and Splicing

(2011) Mari Sepp et al.   PLoS One

Transcriptional regulation of natural killer cell development

(2010) Kevin Ramirez et al.   CURRENT OPINION IN IMMUNOLOGY

Shaping up a lineage—lessons from B lymphopoesis

(2010) David Bryder et al.   CURRENT OPINION IN IMMUNOLOGY

E proteins and the regulation of early lymphocyte development

(2010) Renée F. De Pooter et al.   IMMUNOLOGICAL REVIEWS

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

(2010) Yin C Lin et al.   NATURE IMMUNOLOGY

Two Distinct Motifs within the p53 Transactivation Domain Bind to the Taz2 Domain of p300 and Are Differentially Affected by Phosphorylation†

(2009) Lisa M. Miller Jenkins et al.   BIOCHEMISTRY

Mapping the Interactions of the p53 Transactivation Domain with the KIX Domain of CBP†

(2009) Chul Won Lee et al.   BIOCHEMISTRY

Mixed Lineage Kinase Phosphorylates Transcription Factor E47 and Inhibits TrkB Expression to Link Neuronal Death and Survival Pathways

(2009) Neus Pedraza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomic views of distant-acting enhancers

(2009) Axel Visel et al.   NATURE

Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2

(2009) D P Teufel et al.   ONCOGENE

Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2

(2009) J. C. Ferreon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation

(2009) Hanqiao Feng et al.   STRUCTURE

Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain

(2008) M. Wells et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Recognition of Phosphorylated Transactivation Domains of p53 by Different p300 Domains

(2007) Smarajit Polley et al.   JOURNAL OF MOLECULAR BIOLOGY