DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Mechanical unfolding of human telomere G-quadruplex DNA probed by integrated fluorescence and magnetic tweezers spectroscopy

(2013) Xi Long et al.   NUCLEIC ACIDS RESEARCH

RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity

(2012) Jean-Baptiste Vannier et al.   CELL

Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions

(2012) Anitha Suram et al.   EMBO JOURNAL

The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structures

(2012) Colleen Barefield et al.   NUCLEIC ACIDS RESEARCH

POT1-TPP1 Regulates Telomeric Overhang Structural Dynamics

(2012) Helen Hwang et al.   STRUCTURE

DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase

(2011) Katrin Paeschke et al.   CELL

The in vitro fidelity of yeast DNA polymerase δ and polymerase ɛ holoenzymes during dinucleotide microsatellite DNA synthesis

(2011) Amy L. Abdulovic et al.   DNA REPAIR

Telomerase Is Required to Protect Chromosomes with Vertebrate-type T2AG33′ Ends inSaccharomyces cerevisiae

(2011) Amadou Bah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rudimentary G-quadruplex–based telomere capping in Saccharomyces cerevisiae

(2011) Jasmine S Smith et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Beyond translesion synthesis: polymerase κ fidelity as a potential determinant of microsatellite stability

(2011) Suzanne E. Hile et al.   NUCLEIC ACIDS RESEARCH

Overcoming natural replication barriers: differential helicase requirements

(2011) Ranjith P. Anand et al.   NUCLEIC ACIDS RESEARCH

Telomeric repeat mutagenicity in human somatic cells is modulated by repeat orientation and G-quadruplex stability

(2010) Rama Rao Damerla et al.   DNA REPAIR

Single Molecule Studies of Physiologically Relevant Telomeric Tails Reveal POT1 Mechanism for Promoting G-quadruplex Unfolding

(2010) Hong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FEN1 Ensures Telomere Stability by Facilitating Replication Fork Re-initiation

(2010) Abhishek Saharia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Folding Pathways of Human Telomeric Type-1 and Type-2 G-Quadruplex Structures

(2010) Tomoko Mashimo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

(2009) Agnel Sfeir et al.   CELL

Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN

(2009) N. Arnoult et al.   GENES & DEVELOPMENT

Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice

(2009) P. Martinez et al.   GENES & DEVELOPMENT

The Importance of Negative Superhelicity in Inducing the Formation of G-Quadruplex and i-Motif Structures in the c-Myc Promoter: Implications for Drug Targeting and Control of Gene Expression

(2009) Daekyu Sun et al.   JOURNAL OF MEDICINAL CHEMISTRY

Models for chromosomal replication-independent non-B DNA structure-induced genetic instability

(2009) Guliang Wang et al.   MOLECULAR CARCINOGENESIS

Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase δ

(2009) Michael K Swan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA structure and the Werner protein modulate human DNA polymerase delta-dependent replication dynamics within the common fragile site FRA16D

(2009) Sandeep N. Shah et al.   NUCLEIC ACIDS RESEARCH

Direct visualization of G-quadruplexes in DNA using atomic force microscopy

(2009) Kelly J. Neaves et al.   NUCLEIC ACIDS RESEARCH

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

Structural Diversity and Extreme Stability of UnimolecularOxytricha novaTelomeric G-Quadruplex†

(2008) Ja Yil Lee et al.   BIOCHEMISTRY

Structural Basis of DNA Quadruplex Recognition by an Acridine Drug

(2008) Nancy H. Campbell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Division of Labor at the Eukaryotic Replication Fork

(2008) Stephanie A. Nick McElhinny et al.   MOLECULAR CELL

Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicase

(2008) Gregory Sowd et al.   NUCLEIC ACIDS RESEARCH

Kinetics and mechanism of K+- and Na+-induced folding of models of human telomeric DNA into G-quadruplex structures

(2008) Robert D. Gray et al.   NUCLEIC ACIDS RESEARCH

Telomere ResQue and preservation—Roles for the Werner syndrome protein and other RecQ helicases

(2007) Patricia L. Opresko   MECHANISMS OF AGEING AND DEVELOPMENT