Brief Report: The Differential Roles of mTORC1 and mTORC2 in Mesenchymal Stem Cell Differentiation

mTORC1 signaling controls mammalian skeletal growth through stimulation of protein synthesis

(2014) Jianquan Chen et al.   DEVELOPMENT

Inhibition of Akt/mTOR Attenuates Age-Related Changes in Mesenchymal Stem Cells

(2014) Borzo Gharibi et al.   STEM CELLS

mTORC2 Regulates Mechanically Induced Cytoskeletal Reorganization and Lineage Selection in Marrow-Derived Mesenchymal Stem Cells

(2013) Buer Sen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis

(2012) Ramiro Iglesias-Bartolome et al.   Cell Stem Cell

TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation

(2012) Guiqian Chen et al.   International Journal of Biological Sciences

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

(2012) D. W. Lamming et al.   SCIENCE

mTOR and the differentiation of mesenchymal stem cells

(2011) X. Xiang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

The balance between adipogenesis and osteogenesis in bone regeneration by platelet-rich plasma for age-related osteoporosis

(2011) Hen-Yu Liu et al.   BIOMATERIALS

NVP-BEZ235, a dual pan class I PI3 kinase and mTOR inhibitor, promotes osteogenic differentiation in human mesenchymal stromal cells

(2010) Sally K Martin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

mTOR Mediates Wnt-Induced Epidermal Stem Cell Exhaustion and Aging

(2009) Rogerio M. Castilho et al.   Cell Stem Cell

The effect of rapamycin on bone growth in rabbits

(2009) Chanika Phornphutkul et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Insulin Stimulates Adipogenesis through the Akt-TSC2-mTORC1 Pathway

(2009) Hui H. Zhang et al.   PLoS One

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells

(2009) C. Chen et al.   Science Signaling

Rapamycin Promotes the Osteoblastic Differentiation of Human Embryonic Stem Cells by Blocking the mTOR Pathway and Stimulating the BMP/Smad Pathway

(2009) Kyu-Won Lee et al.   STEM CELLS AND DEVELOPMENT

The TSC-mTOR Pathway Mediates Translational Activation of TOP mRNAs by Insulin Largely in a Raptor- or Rictor-Independent Manner

(2008) I. Patursky-Polischuk et al.   MOLECULAR AND CELLULAR BIOLOGY

A Comprehensive Analysis of the Dual Roles of BMPs in Regulating Adipogenic and Osteogenic Differentiation of Mesenchymal Progenitor Cells

(2008) Quan Kang et al.   STEM CELLS AND DEVELOPMENT

Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3-E1 cells and primary mouse bone marrow stromal cells

(2007) Ujjal K. Singha et al.   JOURNAL OF CELLULAR BIOCHEMISTRY