mTOR and the differentiation of mesenchymal stem cells

Arsenic trioxide promotes senescence and regulates the balance of adipogenic and osteogenic differentiation in human mesenchymal stem cells

(2011) H. Cheng et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

High glucose induces differentiation and adipogenesis in porcine muscle satellite cells via mTOR

(2011) Tao Yue et al.   BMB Reports

IGF-II is regulated by microRNA-125b in skeletal myogenesis

(2011) Yejing Ge et al.   JOURNAL OF CELL BIOLOGY

IGF-I Activation of the AKT Pathway Is Impaired in Visceral But Not Subcutaneous Preadipocytes from Obese Subjects

(2010) Kelly Cleveland-Donovan et al.   ENDOCRINOLOGY

Adenosine 5′-Monophosphate-Activated Protein Kinase-Mammalian Target of Rapamycin Cross Talk Regulates Brown Adipocyte Differentiation

(2010) Rocio Vila-Bedmar et al.   ENDOCRINOLOGY

Sprouty1 is a critical regulatory switch of mesenchymal stem cell lineage allocation

(2010) Sumithra Urs et al.   FASEB JOURNAL

Zinc Finger Protein 467 Is a Novel Regulator of Osteoblast and Adipocyte Commitment

(2010) Julie M. Quach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NVP-BEZ235, a dual pan class I PI3 kinase and mTOR inhibitor, promotes osteogenic differentiation in human mesenchymal stromal cells

(2010) Sally K Martin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis

(2010) Yuting Sun et al.   JOURNAL OF CELL BIOLOGY

Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation

(2010) Keizo Nishikawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Rb regulates fate choice and lineage commitment in vivo

(2010) Eliezer Calo et al.   NATURE

Osteogenic Effects of Rest Inserted and Continuous Cyclic Tensile Strain on hASC Lines with Disparate Osteodifferentiation Capabilities

(2009) Ariel D. Hanson et al.   ANNALS OF BIOMEDICAL ENGINEERING

FGFR1 forms an FRS2-dependent complex with mTOR to regulate smooth muscle marker gene expression

(2009) Pei-Yu Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of PI3K catalytic subunit and Akt isoform deficiency on mTOR and p70S6K activation in myoblasts

(2009) Ronald W. Matheny et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of mammalian target of rapamycin (mTOR) signalling in C2C12 myoblasts prevents myogenic differentiation without affecting the hyperphosphorylation of 4E-BP1

(2009) Mark Willett et al.   CELLULAR SIGNALLING

The mTORC2 Complex Regulates Terminal Differentiation of C2C12 Myoblasts

(2009) L. Shu et al.   MOLECULAR AND CELLULAR BIOLOGY

p70 S6 kinase limits tumor necrosis factor-α-induced interleukin-6 synthesis in osteoblast-like cells

(2009) Chiho Minamitani et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Insulin Stimulates Adipogenesis through the Akt-TSC2-mTORC1 Pathway

(2009) Hui H. Zhang et al.   PLoS One

MEF2C Silencing Attenuates Load-Induced Left Ventricular Hypertrophy by Modulating mTOR/S6K Pathway in Mice

(2009) Ana Helena M. Pereira et al.   PLoS One

TWIST Family of Basic Helix-Loop-Helix Transcription Factors Mediate Human Mesenchymal Stem Cell Growth and Commitment

(2009) Sandra Isenmann et al.   STEM CELLS

Rapamycin Promotes the Osteoblastic Differentiation of Human Embryonic Stem Cells by Blocking the mTOR Pathway and Stimulating the BMP/Smad Pathway

(2009) Kyu-Won Lee et al.   STEM CELLS AND DEVELOPMENT

mTOR Regulates Vascular Smooth Muscle Cell Differentiation From Human Bone Marrow–Derived Mesenchymal Progenitors

(2008) Björn Hegner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Isoform-specific regulation of adipocyte differentiation by Akt/protein kinase Bα

(2008) Sung-Ji Yun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Conditioned media from mouse osteosarcoma cells promote MC3T3-E1 cell proliferation using JAKs and PI3-K/Akt signal crosstalk

(2008) Kanji Mori et al.   CANCER SCIENCE

p70 S6 kinase negatively regulates fibroblast growth factor 2-stimulated interleukin-6 synthesis in osteoblasts: function at a point downstream from protein kinase C

(2008) S Takai et al.   JOURNAL OF ENDOCRINOLOGY

MicroRNAs flex their muscles

(2008) Eva van Rooij et al.   TRENDS IN GENETICS

TNF-α increases protein content in C2C12 and primary myotubes by enhancing protein translation via the TNF-R1, PI3K, and MEK

(2007) Isabelle Plaisance et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Age-related changes in the mechanical properties of the epimysium in skeletal muscles of rats

(2007) Yingxin Gao et al.   JOURNAL OF BIOMECHANICS

Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3-E1 cells and primary mouse bone marrow stromal cells

(2007) Ujjal K. Singha et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Insulin-like growth factor-1 (IGF-1) and leucine activate pig myogenic satellite cells through mammalian target of rapamycin (mTOR) pathway

(2007) Bing Han et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT