Persistent Overexposure to N-Methyl-d-Aspartate (NMDA) Calcium-Dependently Downregulates Glutamine Synthetase, Aquaporin 4, and Kir4.1 Channel in Mouse Cortical Astrocytes
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Title
Persistent Overexposure to N-Methyl-d-Aspartate (NMDA) Calcium-Dependently Downregulates Glutamine Synthetase, Aquaporin 4, and Kir4.1 Channel in Mouse Cortical Astrocytes
Authors
Keywords
Astrocytes, NMDA receptor, GluN1, Glutamine synthetase, Aquaporin 4, Kir4.1, Excitotoxicity
Journal
NEUROTOXICITY RESEARCH
Volume -, Issue -, Pages -
Publisher
Springer Nature America, Inc
Online
2018-09-16
DOI
10.1007/s12640-018-9958-3
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Note: Only part of the references are listed.- Astrocytic GluN2A and GluN2B Oppose the Synaptotoxic Effects of Amyloid-β1-40 in Hippocampal Cells
- (2016) Yan Li et al. JOURNAL OF ALZHEIMERS DISEASE
- Cytokine regulation by modulation of the NMDA receptor on astrocytes
- (2016) Kurt-Wolfram Sühs et al. NEUROSCIENCE LETTERS
- Astrocytes regulate heterogeneity of presynaptic strengths in hippocampal networks
- (2016) Mathieu Letellier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Physiological Roles of Non-Neuronal NMDA Receptors
- (2016) Adam D. Hogan-Cann et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5–Nrf2 pathway
- (2015) D Jimenez-Blasco et al. CELL DEATH AND DIFFERENTIATION
- Astroglial NMDA receptors inhibit expression of Kir4.1 channels in glutamate-overexposed astrocytes in vitro and in the brain of rats with acute liver failure
- (2015) Marta Obara-Michlewska et al. NEUROCHEMISTRY INTERNATIONAL
- A Metabotropic-Like Flux-Independent NMDA Receptor Regulates Ca2+ Exit from Endoplasmic Reticulum and Mitochondrial Membrane Potential in Cultured Astrocytes
- (2015) Pavel Montes de Oca Balderas et al. PLoS One
- Persistent reduction of hippocampal glutamine synthetase expression after status epilepticus in immature rats
- (2014) W. Saskia van der Hel et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- NMDARs in neurological diseases: a potential therapeutic target
- (2014) Janneth Gonzalez et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Dysbalance of Astrocyte Calcium under Hyperammonemic Conditions
- (2014) Nicole Haack et al. PLoS One
- Precipitants of hepatic encephalopathy induce rapid astrocyte swelling in an oxidative stress dependent manner
- (2013) Vera Lachmann et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Astrocytes and Glutamate Homoeostasis in Alzheimer's Disease: A Decrease in Glutamine Synthetase, But Not in Glutamate Transporter-1, in the Prefrontal Cortex
- (2013) Magdalena Kulijewicz-Nawrot et al. ASN Neuro
- Aquaporin and brain diseases
- (2013) Jérôme Badaut et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- NMDA Receptors in Glial Cells: Pending Questions
- (2013) David Dzamba et al. Current Neuropharmacology
- Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA
- (2013) Arne Schousboe et al. Frontiers in Endocrinology
- Inflammatory activation enhances NMDA-triggered Ca2+ signalling and IL-1β secretion in primary cultures of rat astrocytes
- (2012) Franck Gérard et al. BRAIN RESEARCH
- Decreased expression of the glial water channel aquaporin-4 in the intrahippocampal kainic acid model of epileptogenesis
- (2012) Darrin J. Lee et al. EXPERIMENTAL NEUROLOGY
- A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
- (2012) J. J. Iliff et al. Science Translational Medicine
- (1S, 3S)-3-Amino-4-difluoromethylenyl-1-cyclopentanoic Acid (CPP-115), a Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Cocaine Addiction
- (2011) Yue Pan et al. JOURNAL OF MEDICINAL CHEMISTRY
- Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: mechanism for deficient glutamatergic transmission?
- (2011) Markel Olabarria et al. Molecular Neurodegeneration
- [2,4-13C]β-hydroxybutyrate Metabolism in Astrocytes and C6 Glioblastoma Cells
- (2011) Haytham Eloqayli et al. NEUROCHEMICAL RESEARCH
- Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+ signalling in cortical astrocytes
- (2010) Oleg Palygin et al. CELL CALCIUM
- Chemical preconditioning-induced reactive astrocytosis contributes to the reduction of post-ischemic edema through aquaporin-4 downregulation
- (2010) Akihiko Hoshi et al. EXPERIMENTAL NEUROLOGY
- Role of aquaporin-4 in the development of brain oedema in liver failure
- (2010) Gavin Wright et al. JOURNAL OF HEPATOLOGY
- Brain Aquaporin-4 in Experimental Acute Liver Failure
- (2010) Kakulavarapu V. Rama Rao et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Decreased glutamine synthetase, increased citrulline–nitric oxide cycle activities, and oxidative stress in different regions of brain in epilepsy rat model
- (2010) Mummedy Swamy et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- Aquaporin-4 in brain and spinal cord oedema
- (2009) S. Saadoun et al. NEUROSCIENCE
- Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in rats
- (2008) T. Eid et al. BRAIN
- Glutamine synthetase becomes nitrated and its activity is reduced during repetitive seizure activity in the pentylentetrazole model of epilepsy
- (2008) Hans-J. Bidmon et al. EPILEPSIA
- Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses
- (2008) Sofia Papadia et al. NATURE NEUROSCIENCE
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