NMDARs in neurological diseases: a potential therapeutic target

NMDA receptor antagonism potentiates the l-DOPA-induced extracellular dopamine release in the subthalamic nucleus of hemi-parkinson rats

(2014) Anissa El Arfani et al.   NEUROPHARMACOLOGY

Dichotomy in the anxiolytic versus antidepressant effect of C-terminal truncation of the GluN2A subunit of NMDA receptors

(2013) Dragos Inta et al.   BEHAVIOURAL BRAIN RESEARCH

Glutamate-Based Antidepressants: Preclinical Psychopharmacology

(2013) Andrzej Pilc et al.   BIOLOGICAL PSYCHIATRY

New Pharmacological Options for Treating Advanced Parkinson’s Disease

(2013) David Devos et al.   CLINICAL THERAPEUTICS

The plasticity of the association between mu-opioid receptor and glutamate ionotropic receptor N in opioid analgesic tolerance and neuropathic pain

(2013) Pilar Sánchez-Blázquez et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Modulation of NMDA receptor at the synapse: Promising therapeutic interventions in disorders of the nervous system

(2013) Manuela Mellone et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Comparison of Ca2+transients and [Ca2+]iin the dendrites and boutons of non-fast-spiking GABAergic hippocampal interneurons using two-photon laser microscopy and high- and low-affinity dyes

(2013) Máté Kisfali et al.   JOURNAL OF PHYSIOLOGY-LONDON

NMDA receptor as a newly identified member of the metabotropic glutamate receptor family: Clinical implications for neurodegenerative diseases

(2013) ChiHye Chung   MOLECULES AND CELLS

Role of the NMDA receptor in cognitive deficits, anxiety and depressive-like behavior in juvenile and adult mice after neonatal dexamethasone exposure

(2013) Su-Xia Li et al.   NEUROBIOLOGY OF DISEASE

Chronic blockade of extrasynaptic NMDA receptors ameliorates synaptic dysfunction and pro-death signaling in Huntington disease transgenic mice

(2013) Alejandro Dau et al.   NEUROBIOLOGY OF DISEASE

Structure-based discovery of antagonists for GluN3-containing N-methyl-d-aspartate receptors

(2013) Trine Kvist et al.   NEUROPHARMACOLOGY

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Excitotoxicity-induced immediate surge in hippocampal prostanoid production has latent effects that promote chronic progressive neuronal death

(2013) Keisuke Yoshikawa et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Impaired GABAergic Neurotransmission in Schizophrenia Underlies Impairments in Cortical Gamma Band Oscillations

(2013) James M. McNally et al.   Current Psychiatry Reports

Resveratrol Regulates N-Methyl-D-Aspartate Receptor Expression and Suppresses Neuroinflammation in Morphine-Tolerant Rats

(2012) Ru-Yin Tsai et al.   ANESTHESIA AND ANALGESIA

Neuroprotective effect of estrogen: Role of nonsynaptic NR2B-containing NMDA receptors

(2012) Shui-bing Liu et al.   BRAIN RESEARCH BULLETIN

Activation of extrasynaptic NMDA receptors induces LTD in rat hippocampal CA1 neurons

(2012) Dan-dan Liu et al.   BRAIN RESEARCH BULLETIN

Extrasynaptic AMPA receptors in the dorsal horn: Evidence and functional significance

(2012) Olga Kopach et al.   BRAIN RESEARCH BULLETIN

The role of non-synaptic extracellular glutamate

(2012) Manuel Rodriguez et al.   BRAIN RESEARCH BULLETIN

Functional Roles of Synaptic and Extrasynaptic NMDA Receptors in Physiological and Pathological Neuronal Activities

(2012) Sheng-Tian Li et al.   CURRENT DRUG TARGETS

Effect of bFGF on neuronal damage induced by sequential treatment of amyloid β and excitatory amino acid in vitro and in vivo

(2012) Takafumi Noshita et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The antioxidant enzyme peroxiredoxin and its protective role in neurological disorders

(2012) Hong Zhu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Group III and subtype 4 metabotropic glutamate receptor agonists: Discovery and pathophysiological applications in Parkinson's disease

(2012) M. Amalric et al.   NEUROPHARMACOLOGY

Cellular and molecular mechanisms of antioxidants in Parkinson's disease

(2012) Jhon Jairo Sutachan et al.   NUTRITIONAL NEUROSCIENCE

Effects of natural antioxidants in neurodegenerative disease

(2012) Sonia Luz Albarracin et al.   NUTRITIONAL NEUROSCIENCE

NMDA GluN2B receptors involved in the antidepressant effects of curcumin in the forced swim test

(2012) Lin Zhang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Functional activation of glutamate ionotropic receptors in the human peripheral retina

(2011) Clairton F. de Souza et al.   EXPERIMENTAL EYE RESEARCH

Reduction of plasma membrane glutamate transport potentiates insulin but not glucagon secretion in pancreatic islet cells

(2011) Nicole Feldmann et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

GluN2B-containing NMDA receptors as possible targets for the neuroprotective and antidepressant effects of fluoxetine

(2011) Janos P. Kiss et al.   NEUROCHEMISTRY INTERNATIONAL

Gamma synchrony: Towards a translational biomarker for the treatment-resistant symptoms of schizophrenia

(2011) Michael J. Gandal et al.   NEUROPHARMACOLOGY

Neuroprotective and anti-stress effect of A68930 in acute and chronic unpredictable stress model in rats

(2011) Naila Rasheed et al.   NEUROSCIENCE LETTERS

Interactions between ACE inhibitors and classical antiepileptic drugs in the mouse maximal electroshock seizures

(2011) Krzysztof Łukawski et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

N-Methyl-d-aspartate receptor antagonist MK-801 suppresses glial pro-inflammatory cytokine expression in morphine-tolerant rats

(2011) Ching-Hang Liu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Glutamate receptors in preclinical research on Alzheimer's disease: Update on recent advances

(2011) Neng-Wei Hu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

New advances in NMDA receptor pharmacology

(2011) Kevin K. Ogden et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Ionotropic receptors in neuronal–astroglial signalling: What is the role of “excitable” molecules in non-excitable cells

(2010) Ulyana Lalo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Similar anxiolytic-like effects following intra-amygdala infusions of benzodiazepine receptor agonist and antagonist: Evidence for the release of an endogenous benzodiazepine inverse agonist in mice exposed to elevated plus-maze test

(2009) Cilene Aparecida Barbalho et al.   BRAIN RESEARCH

Inhibition of rat recombinant GluN1/GluN2A and GluN1/GluN2B NMDA receptors by ethanol at concentrations based on the US/UK drink-drive limit

(2009) Hannah J. Otton et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes

(2009) Juan E Belforte et al.   NATURE NEUROSCIENCE

Preconditioning neuroprotection in global cerebral ischemia involves NMDA receptor-mediated ERK-JNK3 crosstalk

(2009) Quan-Guang Zhang et al.   NEUROSCIENCE RESEARCH

Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease

(2009) Robert Schwarcz et al.   PROGRESS IN NEUROBIOLOGY

Actin depolymerization contributes to ethanol inhibition of NMDA receptors in primary cultured cerebellar granule cells

(2008) R. Lisa Popp et al.   ALCOHOL

Effects of postnatal dietary choline supplementation on motor regional brain volume and growth factor expression in a mouse model of Rett syndrome

(2008) Nupur Nag et al.   BRAIN RESEARCH

The influence of various glutamate receptors antagonists on anxiety-like effect of ethanol withdrawal in a plus-maze test in rats

(2008) Jolanta Kotlinska et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

In vivo neurochemical effects of the NR2B selective NMDA receptor antagonist CR 3394 in 6-hydroxydopamine lesioned rats

(2008) Sophie Sarre et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

NMDA receptor activity regulates transcription of antioxidant pathways

(2008) Stuart A Lipton   NATURE NEUROSCIENCE

Blockade of NMDA Receptors Prevents Analgesic Tolerance to Repeated Transcutaneous Electrical Nerve Stimulation (TENS) in Rats

(2007) Priyanka M. Hingne et al.   JOURNAL OF PAIN

Antinociceptive effect and interaction of uncompetitive and competitive NMDA receptor antagonists upon capsaicin and paw pressure testing in normal and monoarthritic rats

(2007) Teresa Pelissier et al.   PAIN

Disease-modifying drugs and Parkinson's disease

(2007) Hervé Allain et al.   PROGRESS IN NEUROBIOLOGY

Subtype-Specific Enhancement of NMDA Receptor Currents by Mutant Huntingtin

(2003) Nansheng Chen et al.   JOURNAL OF NEUROCHEMISTRY