Emerging experimental therapies for intracerebral hemorrhage: targeting mechanisms of secondary brain injury

Mild Prolonged Hypothermia for Large Intracerebral Hemorrhage

(2012) Dimitre Staykov et al.   Neurocritical Care

Thrombin and hemin as central factors in the mechanisms of intracerebral hemorrhage–induced secondary brain injury and as potential targets for intervention

(2012) Ranjith Babu et al.   Neurosurgical Focus

Translating Basic Science Research to Clinical Application: Models and Strategies for Intracerebral Hemorrhage

(2012) Christopher C. Leonardo et al.   Frontiers in Neurology

Effects of Atorvastatin on Pathological Changes in Brain Tissue and Plasma MMP-9 in Rats with Intracerebral Hemorrhage

(2011) Jing-Jing Cui et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Ferric iron chelation lowers brain iron levels after intracerebral hemorrhage in rats but does not improve outcome

(2011) Angela M. Auriat et al.   EXPERIMENTAL NEUROLOGY

Experimental Intracerebral Hemorrhage: Avoiding Pitfalls in Translational Research

(2011) Matthew A Kirkman et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH) II: Design, Methods, and Rationale

(2011) A. I. Qureshi et al.   Neurocritical Care

Treatment Targets in Intracerebral Hemorrhage

(2011) Navdeep Sangha et al.   Neurotherapeutics

Minocycline-Induced Attenuation of Iron Overload and Brain Injury After Experimental Intracerebral Hemorrhage

(2011) Fan Zhao et al.   STROKE

Safety and Tolerability of Deferoxamine Mesylate in Patients With Acute Intracerebral Hemorrhage

(2011) Magdy Selim et al.   STROKE

Prospects for Minocycline Neuroprotection

(2010) Jennifer M. Plane et al.   ARCHIVES OF NEUROLOGY

Advances in Neuroprotective Strategies: Potential Therapies for Intracerebral Hemorrhage

(2010) Brian Y. Hwang et al.   CEREBROVASCULAR DISEASES

Iron Toxicity in Mice with Collagenase-Induced Intracerebral Hemorrhage

(2010) He Wu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Long-term histological and behavioural characterisation of a collagenase-induced model of intracerebral haemorrhage in rats

(2010) Virginie Beray-Berthat et al.   JOURNAL OF NEUROSCIENCE METHODS

Vascular recovery promoted by atorvastatin and simvastatin after experimental intracerebral hemorrhage: magnetic resonance imaging and histological study

(2010) Dongmei Yang et al.   JOURNAL OF NEUROSURGERY

Exploring Neuroprotective Drug Therapies for Intracerebral Hemorrhage

(2010) Hiroshi Katsuki   JOURNAL OF PHARMACOLOGICAL SCIENCES

Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis

(2010) Charlotte JJ van Asch et al.   LANCET NEUROLOGY

Deferoxamine Treatment for Intracerebral Hemorrhage in Aged Rats

(2010) Masanobu Okauchi et al.   STROKE

Effects of Early Intensive Blood Pressure-Lowering Treatment on the Growth of Hematoma and Perihematomal Edema in Acute Intracerebral Hemorrhage

(2010) Craig S. Anderson et al.   STROKE

Failure of deferoxamine, an iron chelator, to improve outcome after collagenase-induced intracerebral hemorrhage in rats

(2009) Lindsey M. Warkentin et al.   BRAIN RESEARCH

Treatment of intracerebral hemorrhage in rats with 12 h, 3 days and 6 days of selective brain hypothermia

(2009) Matthew Fingas et al.   EXPERIMENTAL NEUROLOGY

High Serum Levels of Growth Factors Are Associated with Good Outcome in Intracerebral Hemorrhage

(2009) Tomás Sobrino et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Protective Effect of Granulocyte Colony-stimulating Factor on Intracerebral Hemorrhage in Rat

(2009) Lei Zhang et al.   NEUROCHEMICAL RESEARCH

NEUROPROTECTIVE EFFECT OF ERYTHROPOIETIN AND DARBEPOETIN ALFA AFTER EXPERIMENTAL INTRACEREBRAL HEMORRHAGE

(2009) Giovanni Grasso et al.   NEUROSURGERY

Simvastatin and Atorvastatin Improve Neurological Outcome After Experimental Intracerebral Hemorrhage

(2009) Kishor Karki et al.   STROKE

Effects of Deferoxamine on Intracerebral Hemorrhage-Induced Brain Injury in Aged Rats

(2009) Masanobu Okauchi et al.   STROKE

Deferoxamine Reduces Intracerebral Hematoma-Induced Iron Accumulation and Neuronal Death in Piglets

(2009) Yuxiang Gu et al.   STROKE

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

Use of Statins for the Treatment of Spontaneous Intracerebral Hemorrhage: Results of a Pilot Study

(2009) H. Tapia-Perez et al.   Central European neurosurgery

Brain edema after intracerebral hemorrhage in rats: the role of iron overload and aquaporin 4

(2008) Wang Gai Qing et al.   JOURNAL OF NEUROSURGERY

Effect of Delayed Mild Brain Hypothermia on Edema Formation After Intracerebral Hemorrhage in Rats

(2008) Masahiko Kawanishi et al.   Journal of Stroke & Cerebrovascular Diseases

Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial

(2008) Craig S Anderson et al.   LANCET NEUROLOGY

Recombinant hirudin treatment modulates aquaporin-4 and aquaporin-9 expression after intracerebral hemorrhage in vivo

(2008) Zhe Sun et al.   MOLECULAR BIOLOGY REPORTS

Minocycline reduces intracerebral hemorrhage-induced brain injury

(2008) Jimin Wu et al.   NEUROLOGICAL RESEARCH

Efficacy and Safety of Recombinant Activated Factor VII for Acute Intracerebral Hemorrhage

(2008) Stephan A. Mayer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thrombin and Brain Recovery After Intracerebral Hemorrhage

(2008) Y. Hua et al.   STROKE

Effects of Thrombin on Neurogenesis After Intracerebral Hemorrhage

(2008) Shuxu Yang et al.   STROKE

Temporal MRI Assessment of Intracerebral Hemorrhage in Rats

(2008) Robert A. Knight et al.   STROKE