DISC1

Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis

(2012) Anna K. Kähler et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Effects of a mis-sense DISC1 variant on brain activation in two cohorts at high risk of bipolar disorder or schizophrenia

(2012) Heather C. Whalley et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

DISC1 variants 37W and 607F disrupt its nuclear targeting and regulatory role in ATF4-mediated transcription

(2012) Elise L.V. Malavasi et al.   HUMAN MOLECULAR GENETICS

Association of DISC1 variants with age of onset in a population-based sample of recurrent major depression

(2012) P A Thomson et al.   MOLECULAR PSYCHIATRY

Reelin Controls Neuronal Positioning by Promoting Cell-Matrix Adhesion via Inside-Out Activation of Integrin α5β1

(2012) Katsutoshi Sekine et al.   NEURON

The Long and the Short of it: Gene and Environment Interactions During Early Cortical Development and Consequences for Long-Term Neurological Disease

(2012) Helen Stolp et al.   Frontiers in Psychiatry

Human Mutations in NDE1 Cause Extreme Microcephaly with Lissencephaly

(2011) Fowzan S. Alkuraya et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment

(2011) Taku Nagai et al.   BEHAVIOURAL BRAIN RESEARCH

What disorders of cortical development tell us about the cortex: one plus one does not always make two

(2011) M Chiara Manzini et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse

(2011) Keisuke Kuroda et al.   HUMAN MOLECULAR GENETICS

Synaptic Wnt signaling—a contributor to major psychiatric disorders?

(2011) Nathan D. Okerlund et al.   Journal of Neurodevelopmental Disorders

The Outermost Region of the Developing Cortical Plate Is Crucial for Both the Switch of the Radial Migration Mode and the Dab1-Dependent "Inside-Out" Lamination in the Neocortex

(2011) K. Sekine et al.   JOURNAL OF NEUROSCIENCE

Association of white matter integrity with genetic variation in an exonic DISC1 SNP

(2011) E Sprooten et al.   MOLECULAR PSYCHIATRY

Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes

(2011) M A Carless et al.   MOLECULAR PSYCHIATRY

DISC1-dependent switch from progenitor proliferation to migration in the developing cortex

(2011) Koko Ishizuka et al.   NATURE

The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries

(2011) Erich A. Nigg et al.   NATURE CELL BIOLOGY

Linking neurodevelopmental and synaptic theories of mental illness through DISC1

(2011) Nicholas J. Brandon et al.   NATURE REVIEWS NEUROSCIENCE

DISC1 is associated with cortical thickness and neural efficiency

(2011) Stefan Brauns et al.   NEUROIMAGE

Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development

(2011) Karun K. Singh et al.   NEURON

Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice

(2011) Tatiana V. Lipina et al.   NEUROPHARMACOLOGY

In Utero Electroporation as a Tool For Genetic Manipulation In Vivo to Study Psychiatric Disorders

(2011) Yu Taniguchi et al.   NEUROSCIENTIST

Autosomal recessive primary microcephaly (MCPH): clinical manifestations, genetic heterogeneity and mutation continuum

(2011) Saqib Mahmood et al.   Orphanet Journal of Rare Diseases

Prenatal Interaction of Mutant DISC1 and Immune Activation Produces Adult Psychopathology

(2010) Bagrat Abazyan et al.   BIOLOGICAL PSYCHIATRY

Biochemical and Functional Interaction of Disrupted-in-Schizophrenia 1 and Amyloid Precursor Protein Regulates Neuronal Migration during Mammalian Cortical Development

(2010) T. L. Young-Pearse et al.   JOURNAL OF NEUROSCIENCE

Assessing the role of endooligopeptidase activity of Ndel1 (nuclear-distribution gene E homolog like-1) in neurite outgrowth

(2010) Mirian A.F. Hayashi et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Pathway-based approaches to imaging genetics association studies: Wnt signaling, GSK3beta substrates and major depression

(2010) Becky Inkster et al.   NEUROIMAGE

Knockdown of DISC1 by In Utero Gene Transfer Disturbs Postnatal Dopaminergic Maturation in the Frontal Cortex and Leads to Adult Behavioral Deficits

(2010) Minae Niwa et al.   NEURON

Hook3 Interacts with PCM1 to Regulate Pericentriolar Material Assembly and the Timing of Neurogenesis

(2010) Xuecai Ge et al.   NEURON

Disrupted-in-Schizophrenia-1 expression is regulated by  -site amyloid precursor protein cleaving enzyme-1-neuregulin cascade

(2010) S. Seshadri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DISC1 in Schizophrenia: Genetic Mouse Models and Human Genomic Imaging

(2010) M. Johnstone et al.   SCHIZOPHRENIA BULLETIN

Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3

(2010) Tatiana V. Lipina et al.   SYNAPSE

Guiding Neuronal Cell Migrations

(2010) O. Marin et al.   Cold Spring Harbor Perspectives in Biology

Fine Mapping on Chromosome 10q22-q23 Implicates Neuregulin 3 in Schizophrenia

(2009) Pei-Lung Chen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Association of GSK3β Polymorphisms With Brain Structural Changes in Major Depressive Disorder

(2009) Becky Inkster et al.   ARCHIVES OF GENERAL PSYCHIATRY

Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood

(2009) Daisuke Ibi et al.   BEHAVIOURAL BRAIN RESEARCH

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

(2009) Yingwei Mao et al.   CELL

Differences of Migratory Behavior between Direct Progeny of Apical Progenitors and Basal Progenitors in the Developing Cerebral Cortex

(2009) Hidenori Tabata et al.   CEREBRAL CORTEX

Neuropathogenesis of Congenital Cytomegalovirus Infection: Disease Mechanisms and Prospects for Intervention

(2009) M. C.-J. Cheeran et al.   CLINICAL MICROBIOLOGY REVIEWS

Mutations in VLDLR as a Cause for Autosomal Recessive Cerebellar Ataxia With Mental Retardation (Dysequilibrium Syndrome)

(2009) Kym M. Boycott et al.   JOURNAL OF CHILD NEUROLOGY

The Embryonic Preoptic Area Is a Novel Source of Cortical GABAergic Interneurons

(2009) D. M. Gelman et al.   JOURNAL OF NEUROSCIENCE

Regulators of the cytoplasmic dynein motor

(2009) Julia R. Kardon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Disrupted-in-Schizophrenia-1 Ser704Cys polymorphism and brain morphology in schizophrenia

(2009) Tsutomu Takahashi et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Emerging roles for myosin II and cytoplasmic dynein in migrating neurons and growth cones

(2009) Richard B. Vallee et al.   TRENDS IN CELL BIOLOGY

Primary microcephaly: do all roads lead to Rome?

(2009) Gemma K. Thornton et al.   TRENDS IN GENETICS

Molecular layers underlying cytoskeletal remodelling during cortical development

(2009) Julian Ik-Tsen Heng et al.   TRENDS IN NEUROSCIENCES

Association Study of Wnt Signaling Pathway Genes in Bipolar Disorder

(2008) Peter P. Zandi   ARCHIVES OF GENERAL PSYCHIATRY

Recruitment of PCM1 to the Centrosome by the Cooperative Action of DISC1 and BBS4

(2008) Atsushi Kamiya et al.   ARCHIVES OF GENERAL PSYCHIATRY

DISC1, PDE4B, and NDE1 at the centrosome and synapse

(2008) Nicholas J. Bradshaw et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neuroepithelial Stem Cell Proliferation Requires LIS1 for Precise Spindle Orientation and Symmetric Division

(2008) Jessica Yingling et al.   CELL

Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: Evidence of epistasis and competitive binding

(2008) K. E. Burdick et al.   HUMAN MOLECULAR GENETICS

COUP-TFII Is Preferentially Expressed in the Caudal Ganglionic Eminence and Is Involved in the Caudal Migratory Stream

(2008) S. Kanatani et al.   JOURNAL OF NEUROSCIENCE

Schizophrenia-Related Neural and Behavioral Phenotypes in Transgenic Mice Expressing Truncated Disc1

(2008) S. Shen et al.   JOURNAL OF NEUROSCIENCE

Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly

(2008) N Sawamura et al.   MOLECULAR PSYCHIATRY

A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia

(2008) S R Datta et al.   MOLECULAR PSYCHIATRY

Fresh air is good for nerves: hypoxia disturbs axon guidance

(2008) Chun-Liang Pan et al.   NATURE NEUROSCIENCE

Oxygen levels affect axon guidance and neuronal migration in Caenorhabditis elegans

(2008) Roger Pocock et al.   NATURE NEUROSCIENCE

Development of the human cerebral cortex: Boulder Committee revisited

(2008) Irina Bystron et al.   NATURE REVIEWS NEUROSCIENCE

Neuregulin 1 in neural development, synaptic plasticity and schizophrenia

(2008) Lin Mei et al.   NATURE REVIEWS NEUROSCIENCE

Roles of neural stem progenitor cells in cytomegalovirus infection of the brain in mouse models

(2008) Yoshihiro Tsutsui et al.   PATHOLOGY INTERNATIONAL

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

(2008) T. Walsh et al.   SCIENCE

Abnormal development of the human cerebral cortex: genetics, functional consequences and treatment options

(2008) Renzo Guerrini et al.   TRENDS IN NEUROSCIENCES

DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia

(2007) Philip R. Szeszko et al.   BIOLOGICAL PSYCHOLOGY