Synaptic Wnt signaling—a contributor to major psychiatric disorders?

Vangl2 Promotes Wnt/Planar Cell Polarity-like Signaling by Antagonizing Dvl1-Mediated Feedback Inhibition in Growth Cone Guidance

(2011) Beth Shafer et al.   DEVELOPMENTAL CELL

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes

(2010) Jerzy Wegiel et al.   ACTA NEUROPATHOLOGICA

Markers of Glutamate Synaptic Transmission and Plasticity Are Increased in the Anterior Cingulate Cortex in Bipolar Disorder

(2010) Sharon L. Eastwood et al.   BIOLOGICAL PSYCHIATRY

Cognitive and Sensorimotor Gating Impairments in Transgenic Mice Overexpressing the Schizophrenia Susceptibility Gene Tcf4 in the Brain

(2010) Magdalena M. Brzózka et al.   BIOLOGICAL PSYCHIATRY

The neuregulin signaling pathway and schizophrenia: From genes to synapses and neural circuits

(2010) Andrés Buonanno   BRAIN RESEARCH BULLETIN

Planar cell polarity signaling in neural development

(2010) Fadel Tissir et al.   CURRENT OPINION IN NEUROBIOLOGY

Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis

(2010) M. Sahores et al.   DEVELOPMENT

To build a synapse: signaling pathways in neuromuscular junction assembly

(2010) H. Wu et al.   DEVELOPMENT

The involvement of GSK3β in bipolar disorder: Integrating evidence from multiple types of genetic studies

(2010) J.J. Luykx et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Wnt-5a Modulates Recycling of Functional GABAA Receptors on Hippocampal Neurons

(2010) L. Cuitino et al.   JOURNAL OF NEUROSCIENCE

Dact1 Is a Postsynaptic Protein Required for Dendrite, Spine, and Excitatory Synapse Development in the Mouse Forebrain

(2010) N. D. Okerlund et al.   JOURNAL OF NEUROSCIENCE

The nuclear import of Frizzled2-C by Importins-β11 and α2 promotes postsynaptic development

(2010) Timothy J Mosca et al.   NATURE NEUROSCIENCE

Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

(2010) Akiko Hayashi-Takagi et al.   NATURE NEUROSCIENCE

GSK3 signalling in neural development

(2010) Eun-Mi Hur et al.   NATURE REVIEWS NEUROSCIENCE

Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical Development

(2010) Karun K. Singh et al.   NEURON

Intronic Single Nucleotide Polymorphisms of Engrailed Homeobox 2 Modulate the Disease Vulnerability of Autism in a Han Chinese Population

(2010) Pinchen Yang et al.   NEUROPSYCHOBIOLOGY

GSK3 Influences Social Preference and Anxiety-Related Behaviors during Social Interaction in a Mouse Model of Fragile X Syndrome and Autism

(2010) Marjelo A. Mines et al.   PLoS One

Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses

(2010) L. Varela-Nallar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic association study of KREMEN1 and DKK1 and schizophrenia in a Japanese population

(2010) Branko Aleksic et al.   SCHIZOPHRENIA RESEARCH

Wnt signal transduction pathways

(2010) Yuko Komiya et al.   Organogenesis

The Pharmacological Treatment of Bipolar Disorder: The Question of Modern Advances

(2010) Jack Hirschowitz et al.   HARVARD REVIEW OF PSYCHIATRY

Fragile X Mental Retardation Protein Regulates Proliferation and Differentiation of Adult Neural Stem/Progenitor Cells

(2010) Yuping Luo et al.   PLoS Genetics

Structure and function of dendritic spines within the hippocampus

(2009) Oliver von Bohlen und Halbach   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Recurrent Rearrangements in Synaptic and Neurodevelopmental Genes and Shared Biologic Pathways in Schizophrenia, Autism, and Mental Retardation

(2009) Audrey Guilmatre et al.   ARCHIVES OF GENERAL PSYCHIATRY

Altered expression of Autism-associated genes in the brain of Fragile X mouse model

(2009) Aiying Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autism-Associated Haplotype Affects the Regulation of the Homeobox Gene, ENGRAILED 2

(2009) Rym Benayed et al.   BIOLOGICAL PSYCHIATRY

Trans-Synaptic Transmission of Vesicular Wnt Signals through Evi/Wntless

(2009) Ceren Korkut et al.   CELL

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

(2009) Yingwei Mao et al.   CELL

Dishevelled: The hub of Wnt signaling

(2009) Chan Gao et al.   CELLULAR SIGNALLING

A synaptic trek to autism

(2009) Thomas Bourgeron   CURRENT OPINION IN NEUROBIOLOGY

Family-based studies indicate association ofEngrailed 2gene with autism in an Indian population

(2009) B. Sen et al.   GENES BRAIN AND BEHAVIOR

Mutational, functional, and expression studies of theTCF4gene in Pitt-Hopkins syndrome

(2009) Lo��c de Pontual et al.   HUMAN MUTATION

Association between autism and variants in the wingless-type MMTV integration site family member 2 ( WNT2) gene

(2009) Tetsuya Marui et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Wnt-5a/JNK Signaling Promotes the Clustering of PSD-95 in Hippocampal Neurons

(2009) Ginny G. Farías et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dkk-3 is elevated in CSF and plasma of Alzheimer’s disease patients

(2009) Christoph Zenzmaier et al.   JOURNAL OF NEUROCHEMISTRY

Scribble Interacts with β-Catenin to Localize Synaptic Vesicles to Synapses

(2009) Yu Sun et al.   MOLECULAR BIOLOGY OF THE CELL

Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer

(2009) R Tabarés-Seisdedos et al.   MOLECULAR PSYCHIATRY

Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak

(2009) Rowena Suriben et al.   NATURE GENETICS

Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function

(2009) Lorena Varela-Nallar et al.   Neural Development

Wnt signaling in development and disease

(2009) Jennifer L. Freese et al.   NEUROBIOLOGY OF DISEASE

Wnt Signaling Mediates Experience-Related Regulation of Synapse Numbers and Mossy Fiber Connectivities in the Adult Hippocampus

(2009) Nadine Gogolla et al.   NEURON

Ror1-Ror2 complexes modulate synapse formation in hippocampal neurons

(2009) S. Paganoni et al.   NEUROSCIENCE

The State of Synapses in Fragile X Syndrome

(2009) Brad E. Pfeiffer et al.   NEUROSCIENTIST

Genes and signaling events that establish regional patterning of the mammalian forebrain

(2009) Renée V. Hoch et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

GSK3: a multifaceted kinase in Wnt signaling

(2009) Dianqing Wu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Planar Cell Polarity Signaling: The Developing Cell's Compass

(2009) E. K. Vladar et al.   Cold Spring Harbor Perspectives in Biology

Planar Cell Polarity Signaling: From Fly Development to Human Disease

(2008) Matias Simons et al.   Annual Review of Genetics

Association Study of Wnt Signaling Pathway Genes in Bipolar Disorder

(2008) Peter P. Zandi   ARCHIVES OF GENERAL PSYCHIATRY

Generation and behavioral characterization of β-catenin forebrain-specific conditional knock-out mice

(2008) Todd D. Gould et al.   BEHAVIOURAL BRAIN RESEARCH

Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP-2, and β-catenin

(2008) Seung-Hye Lee et al.   JOURNAL OF CELL BIOLOGY

Expression of secreted frizzled related protein 1, a Wnt antagonist, in brain, kidney, and skeleton is dispensable for normal embryonic development

(2008) Brune Trevant et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Presynaptic Local Signaling by a Canonical Wingless Pathway Regulates Development of the Drosophila Neuromuscular Junction

(2008) C. Miech et al.   JOURNAL OF NEUROSCIENCE

Wnt Regulates Axon Behavior through Changes in Microtubule Growth Directionality: A New Role for Adenomatous Polyposis Coli

(2008) S. A. Purro et al.   JOURNAL OF NEUROSCIENCE

Looking at Lithium: Molecular Moods and Complex Behaviour

(2008) J.-M. Beaulieu et al.   MOLECULAR INTERVENTIONS

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

Wnts acting through canonical and noncanonical signaling pathways exert opposite effects on hippocampal synapse formation

(2008) Elizabeth K Davis et al.   Neural Development

The Wnt Antagonist, Dickkopf-1, as a Target for the Treatment of Neurodegenerative Disorders

(2008) Filippo Caraci et al.   NEUROCHEMICAL RESEARCH

Schizophrenia: Genome, Interrupted

(2008) Rita M. Cantor et al.   NEURON

Rapid Activity-Dependent Modifications in Synaptic Structure and Function Require Bidirectional Wnt Signaling

(2008) Bulent Ataman et al.   NEURON

Fragile X Syndrome: Loss of Local mRNA Regulation Alters Synaptic Development and Function

(2008) Gary J. Bassell et al.   NEURON

Association study of GSK3 gene polymorphisms with schizophrenia and clozapine response

(2008) Renan P. Souza et al.   PSYCHOPHARMACOLOGY

GENETICS: Insights into the Pathogenesis of Autism

(2008) J. S. Sutcliffe   SCIENCE

Cadherins and catenins at synapses: roles in synaptogenesis and synaptic plasticity

(2008) Jyothi Arikkath et al.   TRENDS IN NEUROSCIENCES

Murine Dishevelled 3 Functions in Redundant Pathways with Dishevelled 1 and 2 in Normal Cardiac Outflow Tract, Cochlea, and Neural Tube Development

(2008) S. Leah Etheridge et al.   PLoS Genetics

Positional Pathway Screen of wnt Signaling Genes in Schizophrenia: Association with DKK4

(2007) Petroula Proitsi et al.   BIOLOGICAL PSYCHIATRY