Activation of AMPK and its Impact on Exercise Capacity

The Effects of EGCG on Fat Oxidation and Endurance Performance in Male Cyclists

(2016) Sara Dean et al.   INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM

Arctigenin enhances swimming endurance of sedentary rats partially by regulation of antioxidant pathways

(2014) Ruo-ming Wu et al.   ACTA PHARMACOLOGICA SINICA

Exercise performance and peripheral vascular insufficiency improve with AMPK activation in high-fat diet-fed mice

(2014) Kristen A. Baltgalvis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Resveratrol modulates the angiogenic response to exercise training in skeletal muscles of aged men

(2014) Lasse Gliemann et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Salicylate acutely stimulates 5′-AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscles

(2014) Yasuhiro Serizawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Capsaicin suppresses the migration of cholangiocarcinoma cells by down-regulating matrix metalloproteinase-9 expression via the AMPK–NF-κB signaling pathway

(2014) Gong-Rak Lee et al.   CLINICAL & EXPERIMENTAL METASTASIS

AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity

(2014) Louise Lantier et al.   FASEB JOURNAL

Crosstalk between AMPK activation and angiotensin II-induced hypertrophy in cardiomyocytes: the role of mitochondria

(2014) Jessica Soto Hernández et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men

(2014) Jesper Olesen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Fiber hypertrophy and increased oxidative capacity can occur simultaneously in pig glycolytic skeletal muscle

(2013) T. L. Scheffler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mitochondrial and performance adaptations to exercise training in mice lacking skeletal muscle LKB1

(2013) Colby B. Tanner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Angiotensin receptor-mediated oxidative stress is associated with impaired cardiac redox signaling and mitochondrial function in insulin-resistant rats

(2013) José Pablo Vázquez-Medina et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Capsaicin stimulates glucose uptake in C2C12 muscle cells via the reactive oxygen species (ROS)/AMPK/p38 MAPK pathway

(2013) Soon-Hee Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Resveratrol Attenuates Exercise-Induced Adaptive Responses in Rats Selectively Bred for Low Running Performance

(2013) Nikolett Hart et al.   Dose-Response

PPARgamma agonist pioglitazone does not enhance performance in mice

(2013) Fabian Sanchis-Gomar et al.   Drug Testing and Analysis

The therapeutic potential of skeletal muscle plasticity in Duchenne muscular dystrophy: phenotypic modifiers as pharmacologic targets

(2013) Vladimir Ljubicic et al.   FASEB JOURNAL

Resveratrol enhances exercise training responses in rats selectively bred for high running performance

(2013) Nikolett Hart et al.   FOOD AND CHEMICAL TOXICOLOGY

Angiotensin II receptor blocker improves the lowered exercise capacity and impaired mitochondrial function of the skeletal muscle in type 2 diabetic mice

(2013) Shingo Takada et al.   JOURNAL OF APPLIED PHYSIOLOGY

Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men

(2013) Lasse Gliemann et al.   JOURNAL OF PHYSIOLOGY-LONDON

Black Tea High-Molecular-Weight Polyphenol Stimulates Exercise Training-Induced Improvement of Endurance Capacity in Mouse via the Link between AMPK and GLUT4

(2013) Tomoaki Eguchi et al.   PLoS One

AMP-activated protein kinase at the nexus of therapeutic skeletal muscle plasticity in Duchenne muscular dystrophy

(2013) Vladimir Ljubicic et al.   TRENDS IN MOLECULAR MEDICINE

Disconnecting Mitochondrial Content from Respiratory Chain Capacity in PGC-1-Deficient Skeletal Muscle

(2013) Glenn C. Rowe et al.   Cell Reports

AMP-activated protein kinase: new regulation, new roles?

(2012) David Carling et al.   BIOCHEMICAL JOURNAL

Reduced Activity of AMP-Activated Protein Kinase Protects against Genetic Models of Motor Neuron Disease

(2012) M. A. Lim et al.   JOURNAL OF NEUROSCIENCE

Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats

(2012) Vernon W. Dolinsky et al.   JOURNAL OF PHYSIOLOGY-LONDON

Chitooligosaccharide Induces Mitochondrial Biogenesis and Increases Exercise Endurance through the Activation of Sirt1 and AMPK in Rats

(2012) Hyun Woo Jeong et al.   PLoS One

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

(2012) S. A. Hawley et al.   SCIENCE

Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model

(2012) Vanessa E Jahnke et al.   Skeletal Muscle

Of mice and men: The benefits of caloric restriction, exercise, and mimetics

(2011) Evi M. Mercken et al.   AGEING RESEARCH REVIEWS

TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice

(2011) Zhidan Luo et al.   CELL RESEARCH

Treatment with low-dose resveratrol reverses cardiac impairment in obese prone but not in obese resistant rats

(2011) Xavier L. Louis et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Arctigenin Efficiently Enhanced Sedentary Mice Treadmill Endurance

(2011) Xuan Tang et al.   PLoS One

AMP-activated protein kinase (AMPK)  1 2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

(2011) H. M. O'Neill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer’s disease and other tauopathies

(2010) Valérie Vingtdeux et al.   ACTA NEUROPATHOLOGICA

Excitation-transcription coupling in skeletal muscle: the molecular pathways of exercise

(2010) Kristian Gundersen   BIOLOGICAL REVIEWS

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

(2010) Simon A. Hawley et al.   Cell Metabolism

Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation

(2010) Valérie Vingtdeux et al.   FASEB JOURNAL

Angiotensin II receptor blocker telmisartan enhances running endurance of skeletal muscle through activation of the PPAR-δ/AMPK pathway

(2010) Xiaoli Feng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

AMPK and the biochemistry of exercise: implications for human health and disease

(2009) Erik A. Richter et al.   BIOCHEMICAL JOURNAL

Novel pharmacological approaches to combat obesity and insulin resistance: targeting skeletal muscle with ‘exercise mimetics’

(2009) A. L. Carey et al.   DIABETOLOGIA

Skeletal Muscle AMP-activated Protein Kinase Is Essential for the Metabolic Response to Exercisein Vivo

(2009) Robert S. Lee-Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Candesartan Improves Maximal Exercise Capacity in Hypertensives: Results of a Randomized Placebo-Controlled Crossover Trial

(2009) Maria Leonarda De Rosa et al.   Journal of Clinical Hypertension

Lack of adequate appreciation of physical exercise's complexities can pre-empt appropriate design and interpretation in scientific discovery

(2009) F. W. Booth et al.   JOURNAL OF PHYSIOLOGY-LONDON

Impact of metformin on peak aerobic capacity

(2008) Barry Braun et al.   Applied Physiology Nutrition and Metabolism

AMPK and PPARδ Agonists Are Exercise Mimetics

(2008) Vihang A. Narkar et al.   CELL

Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes

(2008) John W. Scott et al.   CHEMISTRY & BIOLOGY

Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients

(2008) H. Boon et al.   DIABETOLOGIA

Acute effect of metformin on exercise capacity in active males

(2007) S. T. Johnson et al.   DIABETES OBESITY & METABOLISM

Contrasting effects of exercise, AICAR, and increased fatty acid supply on in vivo and skeletal muscle glucose metabolism

(2007) C. Rantzau et al.   JOURNAL OF APPLIED PHYSIOLOGY