The Dopamine Stabilizer (−)-OSU6162 Occupies a Subpopulation of Striatal Dopamine D2/D3 Receptors: An [11C]Raclopride PET Study in Healthy Human Subjects

Rostrocaudal gradients of dopamine D2/3 receptor binding in striatal subregions measured with [11C]raclopride and high-resolution positron emission tomography

(2013) Kati Alakurtti et al.   NEUROIMAGE

Placebo-controlled cross-over study of the monoaminergic stabiliser (−)-OSU6162 in mental fatigue following stroke or traumatic brain injury.

(2012) Birgitta Johansson et al.   ACTA NEUROPSYCHIATRICA

In vivo quantification of striatal dopamine D2 receptor occupancy by JNJ-37822681 using [11C]raclopride and positron emission tomography

(2012) Erik T te Beek et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The dopamine stabilizers ACR16 and (−)-OSU6162 display nanomolar affinities at the σ-1 receptor

(2012) K Sahlholm et al.   MOLECULAR PSYCHIATRY

No association between bone mass and prolactin levels among patients with schizophrenia

(2011) Norio Sugawara et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

II. In vitro evidence that (−)-OSU6162 and (+)-OSU6162 produce their behavioral effects through 5-HT2A serotonin and D2 dopamine receptors

(2011) Ethan S. Burstein et al.   JOURNAL OF NEURAL TRANSMISSION

I. In vivo evidence for partial agonist effects of (−)-OSU6162 and (+)-OSU6162 on 5-HT2A serotonin receptors

(2011) Maria L. Carlsson et al.   JOURNAL OF NEURAL TRANSMISSION

Effects of the dopamine stabilizers (S)-(-)-OSU6162 and ACR16 on prolactin secretion in drug-naive and monoamine-depleted rats

(2011) Johan P. Rung et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Analysis of the actions of the novel dopamine receptor-directed compounds (S)-OSU6162 and ACR16 at the D2 dopamine receptor

(2010) Elodie Kara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Application of Stable Isotope Methodology in the Evaluation of the Pharmacokinetics of (S,S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine Hydrochloride in Rats

(2009) S. Yamazaki et al.   DRUG METABOLISM AND DISPOSITION

The dopaminergic stabilizers pridopidine (ACR16) and (−)-OSU6162 display dopamine D2 receptor antagonism and fast receptor dissociation properties

(2009) Tino Dyhring et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Co-operativity in agonist binding at the D2dopamine receptor: evidence from agonist dissociation kinetics

(2009) Elodie Kara et al.   JOURNAL OF NEUROCHEMISTRY

Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation

(2009) Yang Han et al.   Nature Chemical Biology

Effects of (−)-OSU6162 and ACR16 on motor activity in rats, indicating a unique mechanism of dopaminergic stabilization

(2008) Johan P. Rung et al.   JOURNAL OF NEURAL TRANSMISSION