Animal modelling of traumatic brain injury in preclinical drug development: where do we go from here?
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Title
Animal modelling of traumatic brain injury in preclinical drug development: where do we go from here?
Authors
Keywords
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Journal
BRITISH JOURNAL OF PHARMACOLOGY
Volume 164, Issue 4, Pages 1207-1229
Publisher
Wiley
Online
2010-12-23
DOI
10.1111/j.1476-5381.2010.01163.x
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Note: Only part of the references are listed.- The Psychiatric Sequelae of Traumatic Injury
- (2010) Richard A. Bryant et al. AMERICAN JOURNAL OF PSYCHIATRY
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- (2010) William M. Armstead et al. BRAIN RESEARCH
- Association of the severity of cortical damage with the occurrence of spontaneous seizures and hyperexcitability in an animal model of posttraumatic epilepsy
- (2010) Irina Kharatishvili et al. EPILEPSY RESEARCH
- Measuring Outcome in Traumatic Brain Injury Treatment Trials
- (2010) Emilia Bagiella et al. JOURNAL OF HEAD TRAUMA REHABILITATION
- The Epidemiology of Traumatic Brain Injury
- (2010) John D. Corrigan et al. JOURNAL OF HEAD TRAUMA REHABILITATION
- A comparison of two cognitive test paradigms in a penetrating brain injury model
- (2010) Angela R. Davis et al. JOURNAL OF NEUROSCIENCE METHODS
- Genetic Deletion and Pharmacological Inhibition of Nogo-66 Receptor Impairs Cognitive Outcome after Traumatic Brain Injury in Mice
- (2010) Anders Hånell et al. JOURNAL OF NEUROTRAUMA
- Age-Related Mitochondrial Changes after Traumatic Brain Injury
- (2010) Lesley K. Gilmer et al. JOURNAL OF NEUROTRAUMA
- Empirical Comparison of Typical and Atypical Environmental Enrichment Paradigms on Functional and Histological Outcome after Experimental Traumatic Brain Injury
- (2010) Christopher N. Sozda et al. JOURNAL OF NEUROTRAUMA
- Membrane Neovascularization and Drainage of Subdural Hematoma in a Rat Model
- (2010) Dong Wang et al. JOURNAL OF NEUROTRAUMA
- Post-Traumatic Hypoxia Exacerbates Brain Tissue Damage: Analysis of Axonal Injury and Glial Responses
- (2010) Sarah C. Hellewell et al. JOURNAL OF NEUROTRAUMA
- Mild Fluid Percussion Injury in Mice Produces Evolving Selective Axonal Pathology and Cognitive Deficits Relevant to Human Brain Injury
- (2010) Aisling Spain et al. JOURNAL OF NEUROTRAUMA
- The Multivariate Concentric Square Field Test Reveals Behavioral Profiles of Risk Taking, Exploration, and Cognitive Impairment in Mice Subjected to Traumatic Brain Injury
- (2010) Sara Ekmark-Lewén et al. JOURNAL OF NEUROTRAUMA
- Spontaneous Epileptiform Activity in Rat Neocortex after Controlled Cortical Impact Injury
- (2010) Lie Yang et al. JOURNAL OF NEUROTRAUMA
- Strain-Related Differences after Experimental Traumatic Brain Injury in Rats
- (2010) Wendy Murdock Reid et al. JOURNAL OF NEUROTRAUMA
- Traumatic Brain Injury: A Disease Process, Not an Event
- (2010) Brent E. Masel et al. JOURNAL OF NEUROTRAUMA
- Development of a rat model for studying blast-induced traumatic brain injury
- (2010) Jingmin Cheng et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Fluid-percussion–induced traumatic brain injury model in rats
- (2010) Shruti V Kabadi et al. Nature Protocols
- Mechanisms of blast induced brain injuries, experimental studies in rats
- (2010) M. Risling et al. NEUROIMAGE
- Diffuse axonal injury induced by simultaneous moderate linear and angular head accelerations in rats
- (2010) X.Y. Li et al. NEUROSCIENCE
- Angiotensin-converting enzyme (ACE) inhibitors exacerbate histological damage and motor deficits after experimental traumatic brain injury
- (2010) Elizabeth Harford-Wright et al. NEUROSCIENCE LETTERS
- Genetic association studies in patients with traumatic brain injury
- (2010) Efthimios Dardiotis et al. Neurosurgical Focus
- Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury
- (2010) Jenna M. Ziebell et al. Neurotherapeutics
- Antioxidant therapies for traumatic brain injury
- (2010) Edward D. Hall et al. Neurotherapeutics
- Biomarkers for the diagnosis, prognosis, and evaluation of treatment efficacy for traumatic brain injury
- (2010) Pramod K. Dash et al. Neurotherapeutics
- Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies
- (2010) David J. Loane et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Genetic regulation of microglia activation, complement expression, and neurodegeneration in a rat model of traumatic brain injury
- (2010) Bo-Michael Bellander et al. EXPERIMENTAL BRAIN RESEARCH
- Morphologic and Biochemical Characterization of Brain Injury in a Model of Controlled Blast Overpressure Exposure
- (2010) Stanislav I. Svetlov et al. JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
- Dual functionality of interleukin-1 family cytokines: implications for anti-interleukin-1 therapy
- (2009) NM Luheshi et al. BRITISH JOURNAL OF PHARMACOLOGY
- Neutralization of interleukin-1β modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice
- (2009) Fredrik Clausen et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- The role of mitochondrial transition pore, and its modulation, in traumatic brain injury and delayed neurodegeneration after TBI
- (2009) Anna Teresa Mazzeo et al. EXPERIMENTAL NEUROLOGY
- Cyclosporine A for neuroprotection: establishing dosing guidelines for safe and effective use
- (2009) Aaron M Cook et al. Expert Opinion On Drug Safety
- Systemic inflammatory response following acute traumatic brain injury
- (2009) Jia Lu Frontiers in Bioscience-Landmark
- Can we improve neurological outcomes in severe traumatic brain injury?
- (2009) Alistair D. Nichol et al. INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
- The Adverse Pial Arteriolar and Axonal Consequences of Traumatic Brain Injury Complicated by Hypoxia and Their Therapeutic Modulation with Hypothermia in Rat
- (2009) Guoyi Gao et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
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- (2009) Nicholas P. Whitney et al. JOURNAL OF NEUROCHEMISTRY
- Monitoring of brain interstitial total tau and beta amyloid proteins by microdialysis in patients with traumatic brain injury
- (2009) Niklas Marklund et al. JOURNAL OF NEUROSURGERY
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- (2009) Pasquale De Bonis et al. JOURNAL OF NEUROSURGERY
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- (2009) Michael Kilbourne et al. JOURNAL OF NEUROTRAUMA
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- (2009) Xi-Chun May Lu et al. JOURNAL OF NEUROTRAUMA
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- (2009) Arlene A. Tan et al. JOURNAL OF NEUROTRAUMA
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- (2009) Brian J. Blyth et al. JOURNAL OF NEUROTRAUMA
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- (2009) Symeon Missios et al. JOURNAL OF NEUROTRAUMA
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- (2009) Murat Imer et al. NEUROLOGICAL RESEARCH
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- (2009) P.K. Dash et al. NEUROSCIENCE
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- (2009) Deborah A. Shear et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Magnetic Resonance Imaging Evidence of Progression of Subacute Brain Atrophy in Moderate to Severe Traumatic Brain Injury
- (2008) Kevin Ng et al. ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
- Use of Diffusion Tensor Imaging to Examine Subacute White Matter Injury Progression in Moderate to Severe Traumatic Brain Injury
- (2008) Gahl Greenberg et al. ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
- Delivery of peptides to the brain: Emphasis on therapeutic development
- (2008) William A. Banks BIOPOLYMERS
- Duration of ATP reduction affects extent of CA1 cell death in rat models of fluid percussion injury combined with secondary ischemia
- (2008) Naoki Aoyama et al. BRAIN RESEARCH
- Making Decisions and Advising Decisions in Traumatic Brain Injury
- (2008) Elisabeth Bonatti et al. Cognitive and Behavioral Neurology
- Nonischemic energy metabolic crisis in acute brain injury*
- (2008) Lars Hillered et al. CRITICAL CARE MEDICINE
- Unique challenges in clinical trials in traumatic brain injury
- (2008) David K. Menon CRITICAL CARE MEDICINE
- Epidemiology, treatment and outcome of patients after severe traumatic brain injury in European regions with different economic status
- (2008) W. Mauritz et al. EUROPEAN JOURNAL OF PUBLIC HEALTH
- Hemostatic and neuroprotective effects of human recombinant activated factor VII therapy after traumatic brain injury in pigs
- (2008) Jun Zhang et al. EXPERIMENTAL NEUROLOGY
- Posttraumatic epilepsy after controlled cortical impact injury in mice
- (2008) Robert F. Hunt et al. EXPERIMENTAL NEUROLOGY
- Gender differences in outcome in patients with hypotension and severe traumatic brain injury
- (2008) Jennie L. Ponsford et al. INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
- Role of Cortical Spreading Depressions for Secondary Brain Damage after Traumatic Brain Injury in Mice
- (2008) Louisa von Baumgarten et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
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- (2008) Jimmi Hatton et al. JOURNAL OF NEUROSURGERY
- Distinct Cellular Patterns of Upregulated Chemokine Expression Supporting a Prominent Inflammatory Role in Traumatic Brain Injury
- (2008) Charlotte Israelsson et al. JOURNAL OF NEUROTRAUMA
- Evolution of Post-Traumatic Neurodegeneration after Controlled Cortical Impact Traumatic Brain Injury in Mice and Rats as Assessed by the De Olmos Silver and Fluorojade Staining Methods
- (2008) Edward D. Hall et al. JOURNAL OF NEUROTRAUMA
- Classification of Traumatic Brain Injury for Targeted Therapies
- (2008) Kathryn E. Saatman et al. JOURNAL OF NEUROTRAUMA
- Experimental Traumatic Brain Injury Induces a Pervasive Hyperanxious Phenotype in Rats
- (2008) Nigel C. Jones et al. JOURNAL OF NEUROTRAUMA
- Moderate and severe traumatic brain injury in adults
- (2008) Andrew IR Maas et al. LANCET NEUROLOGY
- Biochemical effects of experimental epidural hematoma on brain parenchyma of rats
- (2008) Mahmut Balikci et al. NEUROLOGICAL RESEARCH
- Graded model of diffuse axonal injury for studying head injury-induced cognitive dysfunction in rats
- (2008) Katsuhiko Maruichi et al. NEUROPATHOLOGY
- Amyloid- Dynamics Correlate with Neurological Status in the Injured Human Brain
- (2008) D. L. Brody et al. SCIENCE
- Environmental enrichment-mediated functional improvement after experimental traumatic brain injury is contingent on task-specific neurobehavioral experience
- (2007) Ann N. Hoffman et al. NEUROSCIENCE LETTERS
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