The metabotropic glutamate receptor antagonist 2-methyl-6-(phenylethynyl) pyridine decreases striatal VGlut2 expression in association with an attenuation of L-dopa-induced dyskinesias

Glutamate Receptors as Therapeutic Targets for Parkinsons Disease

(2012) Kari Johnson et al.   CNS & Neurological Disorders-Drug Targets

Reduction of L-DOPA-Induced Dyskinesia by the Selective Metabotropic Glutamate Receptor 5 Antagonist 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Lesioned Macaque Model of Parkinson's Disease

(2010) T. H. Johnston et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Biphasic and bilateral changes in striatal VGLUT1 and 2 protein expression in hemi-Parkinson rats

(2010) Ann Massie et al.   NEUROCHEMISTRY INTERNATIONAL

Effect of the metabotropic glutamate receptor type 5 antagonists MPEP and MTEP in parkinsonian monkeys

(2010) Nicolas Morin et al.   NEUROPHARMACOLOGY

Pharmacological Modulation of Glutamate Transmission in a Rat Model of L-DOPA-Induced Dyskinesia: Effects on Motor Behavior and Striatal Nuclear Signaling

(2009) D. Rylander et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Inhibitory effect of glutamate release from rat cerebrocortical synaptosomes by dextromethorphan and its metabolite 3-hydroxymorphinan

(2009) Tzu-Yu Lin et al.   NEUROCHEMISTRY INTERNATIONAL

Metabotropic glutamate mGluR5 receptor blockade opposes abnormal involuntary movements and the increases in glutamic acid decarboxylase mRNA levels induced by l-DOPA in striatal neurons of 6-hydroxydopamine-lesioned rats

(2009) N. Yamamoto et al.   NEUROSCIENCE

Effect of the metabotropic glutamate antagonist MPEP on striatal expression of the Homer family proteins in levodopa-treated hemiparkinsonian rats

(2009) Anna Jiménez et al.   PSYCHOPHARMACOLOGY

The search for a role of the caudal intralaminar nuclei in the pathophysiology of Parkinson’s disease

(2008) José L. Lanciego et al.   BRAIN RESEARCH BULLETIN

The thalamostriatal systems: Anatomical and functional organization in normal and parkinsonian states

(2008) Yoland Smith et al.   BRAIN RESEARCH BULLETIN

Multi-target strategy for Parkinsonian patients: The role of deep brain stimulation in the centromedian–parafascicularis complex

(2008) Alessandro Stefani et al.   BRAIN RESEARCH BULLETIN

Targeting the caudal intralaminar nuclei for functional neurosurgery of movement disorders

(2008) Alim Louis Benabid   BRAIN RESEARCH BULLETIN

Differential synaptic plasticity of the corticostriatal and thalamostriatal systems in an MPTP-treated monkey model of parkinsonism

(2008) Dinesh V. Raju et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Investigation on tolerance development to subchronic blockade of mGluR5 in models of learning, anxiety, and levodopa-induced dyskinesia in rats

(2008) Andreas Gravius et al.   JOURNAL OF NEURAL TRANSMISSION

Glutamatergic pallidothalamic projections and their implications in the pathophysiology of Parkinson’s disease

(2008) Pedro Barroso-Chinea et al.   NEUROBIOLOGY OF DISEASE

mGluR5 metabotropic glutamate receptors and dyskinesias in MPTP monkeys

(2007) Pershia Samadi et al.   NEUROBIOLOGY OF AGING

Systemic administration of an mGluR5 antagonist, but not unilateral subthalamic lesion, counteracts l-DOPA-induced dyskinesias in a rodent model of Parkinson's disease

(2007) Giovanna Levandis et al.   NEUROBIOLOGY OF DISEASE