The effect of dexmedetomidine on inflammatory inhibition and microglial polarization in BV-2 cells

Protection of Dexmedetomidine Against Ischemia/Reperfusion-Induced Apoptotic Insults to Neuronal Cells Occurs Via an Intrinsic Mitochondria-Dependent Pathway

(2017) Gong-Jhe Wu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The protective effects of dexmedetomidine on ischemic brain injury: A meta-analysis

(2017) Lianxiang Jiang et al.   JOURNAL OF CLINICAL ANESTHESIA

Rictor/mammalian target of rapamycin complex 2 promotes macrophage activation and kidney fibrosis

(2017) Jiafa Ren et al.   JOURNAL OF PATHOLOGY

High glucose induces alternative activation of macrophages via PI3K/Akt signaling pathway

(2017) Jie Wang et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Neurodegenerative changes and neuroapoptosis induced by systemic lipopolysaccharide administration are reversed by dexmedetomidine treatment in mice

(2017) Qiaoqing Ning et al.   NEUROLOGICAL RESEARCH

Pharmacological Modulation of Functional Phenotypes of Microglia in Neurodegenerative Diseases

(2017) Gyun Jee Song et al.   Frontiers in Aging Neuroscience

Neuroprotective effects of dexmedetomidine against hyperoxia-induced injury in the developing rat brain

(2017) Stefanie Endesfelder et al.   PLoS One

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Protective role of dexmedetomidine in unmethylated CpG-induced inflammation responses in BV2 microglia cells

(2016) Chen Chen et al.   FOLIA NEUROPATHOLOGICA

Dexmedetomidine attenuates inflammatory reaction in the lung tissues of septic mice by activating cholinergic anti-inflammatory pathway

(2016) Zhaoguo Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dexmedetomidine pretreatment attenuates propofol-induced neurotoxicity in neuronal cultures from the rat hippocampus

(2016) Yi Wei et al.   Molecular Medicine Reports

Functions and mechanisms of microglia/macrophages in neuroinflammation and neurogenesis after stroke

(2016) Xiao-Yi Xiong et al.   PROGRESS IN NEUROBIOLOGY

Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation

(2015) Emiliano Peña-Altamira et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Pharmacological effects of mitraphylline from Uncaria tomentosa in primary human monocytes: Skew toward M2 macrophages

(2015) S. Montserrat-de la Paz et al.   JOURNAL OF ETHNOPHARMACOLOGY

Microglia and neuroprotection

(2015) Zhihong Chen et al.   JOURNAL OF NEUROCHEMISTRY

The Effect of Dexmedetomidine Post-treatment on the Inflammatory Response of Astrocyte Induced by Lipopolysaccharide

(2014) Cuiying Xie et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Dexmedetomidine inhibits inducible nitric oxide synthase in lipopolysaccharide-stimulated microglia by suppression of extracellular signal-regulated kinase

(2014) Xiaobao Zhang et al.   NEUROLOGICAL RESEARCH

Facilitatory effects of perineural dexmedetomidine on neuraxial and peripheral nerve block: a systematic review and meta-analysis

(2013) F.W. Abdallah et al.   BRITISH JOURNAL OF ANAESTHESIA

Neural and Immune Mechanisms in the Pathogenesis of Parkinson’s Disease

(2013) Fabio Blandini   Journal of Neuroimmune Pharmacology

Dexmedetomidine attenuates lipopolysaccharide-induced proinflammatory response in primary microglia

(2012) Mian Peng et al.   JOURNAL OF SURGICAL RESEARCH

A high dose of dexmedetomidine using the BIS monitor™ for diagnostic and interventional cardiac catheterization in a toddler with congenital heart disease

(2011) Takayuki Kunisawa et al.   Journal of Anesthesia

Caspase signalling controls microglia activation and neurotoxicity

(2011) Miguel A. Burguillos et al.   NATURE