Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death

CHOP regulates the p53–MDM2 axis and is required for neuronal survival after seizures

(2013) Tobias Engel et al.   BRAIN

BH3-only protein silencing contributes to acquired resistance to PLX4720 in human melanoma

(2012) Y Shao et al.   CELL DEATH AND DIFFERENTIATION

Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects

(2012) Eva M Jimenez-Mateos et al.   NATURE MEDICINE

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Energy depletion in seizures: Anaplerosis as a strategy for future therapies

(2012) Stjepana Kovac et al.   NEUROPHARMACOLOGY

Minor cell-death defects but reduced tumor latency in mice lacking the BH3-only proteins Bad and Bmf

(2012) F Baumgartner et al.   ONCOGENE

miRNA Expression Profile after Status Epilepticus and Hippocampal Neuroprotection by Targeting miR-132

(2011) Eva M. Jimenez-Mateos et al.   AMERICAN JOURNAL OF PATHOLOGY

Bcl-2-Modifying Factor Induces Renal Proximal Tubular Cell Apoptosis in Diabetic Mice

(2011) G. J. Lau et al.   DIABETES

Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice

(2011) Tobias Engel et al.   FASEB JOURNAL

BCL-2 Modifying Factor (BMF) Is a Central Regulator of Anoikis in Human Intestinal Epithelial Cells

(2011) Martin Hausmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo Contributions of BH3-Only Proteins to Neuronal Death Following Seizures, Ischemia, and Traumatic Brain Injury

(2011) Tobias Engel et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

Nonapoptotic Function of BAD and BAX in Long-Term Depression of Synaptic Transmission

(2011) Song Jiao et al.   NEURON

Adenosine monophosphate-activated protein kinase and peroxisome proliferator-activated receptor gamma coactivator 1α signaling provides neuroprotection in status epilepticus in rats

(2011) Yuxiang Han et al.   NEUROSCIENCE LETTERS

BH3-only proteins: Orchestrators of apoptosis

(2010) Aisha Shamas-Din et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

BH3-only protein Bmf mediates apoptosis upon inhibition of CAP-dependent protein synthesis

(2010) F Grespi et al.   CELL DEATH AND DIFFERENTIATION

AMP-activated Protein Kinase Mediates Apoptosis in Response to Bioenergetic Stress through Activation of the Pro-apoptotic Bcl-2 Homology Domain-3-only Protein BMF

(2010) Seán M. Kilbride et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BH3 Domains other than Bim and Bid Can Directly Activate Bax/Bak

(2010) Han Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BH3-only protein Bid is dispensable for seizure-induced neuronal death and the associated nuclear accumulation of apoptosis-inducing factor

(2010) Tobias Engel et al.   JOURNAL OF NEUROCHEMISTRY

Deletion of puma protects hippocampal neurons in a model of severe status epilepticus

(2010) T. Engel et al.   NEUROSCIENCE

BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program

(2010) D. Ren et al.   SCIENCE

Loss of p53 results in protracted electrographic seizures and development of an aggravated epileptic phenotype following status epilepticus

(2010) T Engel et al.   Cell Death & Disease

Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus

(2009) B M Murphy et al.   CELL DEATH AND DIFFERENTIATION

Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsies

(2009) Michael Wong   EPILEPSIA

Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma

(2009) Tobias Engel et al.   FASEB JOURNAL

Functional Cooperation of the Proapoptotic Bcl2 Family Proteins Bmf and Bim In Vivo

(2009) A. Hubner et al.   MOLECULAR AND CELLULAR BIOLOGY

Bmf is upregulated by PS-341-mediated cell death of glioma cells through JNK phosphorylation

(2009) Zheng Tianhu et al.   MOLECULAR BIOLOGY REPORTS

Bim and Bmf in tissue homeostasis and malignant disease

(2009) J D Piñon et al.   ONCOGENE

BH3-only proteins Noxa, Bmf, and Bim are necessary for arsenic trioxide-induced cell death in myeloma

(2008) A. A. Morales et al.   BLOOD

Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice

(2008) Genshin Mouri et al.   BRAIN RESEARCH

Phosphorylation of Bad at Thr-201 by JNK1 Promotes Glycolysis through Activation of Phosphofructokinase-1

(2008) Hongbin Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells

(2008) Hewang Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates γ irradiation–induced thymic lymphoma development

(2008) Verena Labi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Temporal expression of AMP-activated protein kinase activation during the kainic acid-induced hippocampal cell death

(2008) Ji Yeong Lee et al.   JOURNAL OF NEURAL TRANSMISSION

The Proapoptotic BCL-2 Homology Domain 3-Only Protein Bim Is Not Critical for Acute Excitotoxic Cell Death

(2008) Panos Theofilas et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways

(2008) Eva M. Jimenez-Mateos et al.   NEUROBIOLOGY OF DISEASE