AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

(2010) Simon A. Hawley et al.   Cell Metabolism

Lkb1 inactivation is sufficient to drive endometrial cancers that are aggressive yet highly responsive to mTOR inhibitor monotherapy

(2010) C. M. Contreras et al.   Disease Models & Mechanisms

Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase

(2010) J. Mankouri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ion Channel Regulation by AMPK

(2009) A. Mark Evans et al.   Annals of the New York Academy of Sciences

Calmodulin-dependent protein kinase kinase-β activates AMPK without forming a stable complex: synergistic effects of Ca2+and AMP

(2009) Sarah Fogarty et al.   BIOCHEMICAL JOURNAL

Histological evaluation of AMPK signalling in primary breast cancer

(2009) Sirwan M Hadad et al.   BMC CANCER

A cohort study of the risk of cancer associated with type 2 diabetes

(2009) A A Ogunleye et al.   BRITISH JOURNAL OF CANCER

Metformin use and prostate cancer in Caucasian men: results from a population-based case–control study

(2009) Jonathan L. Wright et al.   CANCER CAUSES & CONTROL

The Glycogen-Binding Domain on the AMPK β Subunit Allows the Kinase to Act as a Glycogen Sensor

(2009) Andrew McBride et al.   Cell Metabolism

The influence of glucose-lowering therapies on cancer risk in type 2 diabetes

(2009) C. J. Currie et al.   DIABETOLOGIA

TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells

(2009) Griselda Herrero-Martín et al.   EMBO JOURNAL

Antidiabetic Therapies Affect Risk of Pancreatic Cancer

(2009) Donghui Li et al.   GASTROENTEROLOGY

Metformin and Pathologic Complete Responses to Neoadjuvant Chemotherapy in Diabetic Patients With Breast Cancer

(2009) Sao Jiralerspong et al.   JOURNAL OF CLINICAL ONCOLOGY

Association of AMP-activated Protein Kinase Subunits With Glycogen Particles as Revealed In Situ by Immunoelectron Microscopy

(2009) Moise Bendayan et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Oncogenic B-RAF Negatively Regulates the Tumor Suppressor LKB1 to Promote Melanoma Cell Proliferation

(2009) Bin Zheng et al.   MOLECULAR CELL

Structural insight into the autoinhibition mechanism of AMP-activated protein kinase

(2009) Lei Chen et al.   NATURE

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Somatic LKB1 Mutations Promote Cervical Cancer Progression

(2009) Shana N. Wingo et al.   PLoS One

Antidiabetic therapy and increased risk of hepatocellular carcinoma in chronic liver disease

(2009) Valter Donadon et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Sulphonylureas and cancer: a case–control study

(2008) Matteo Monami et al.   ACTA DIABETOLOGICA

The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways

(2008) Jiyun Ahn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice

(2008) Xu Huang et al.   BIOCHEMICAL JOURNAL

Mechanisms underlying the metabolic actions of galegine that contribute to weight loss in mice

(2008) M H Mooney et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lkb1 Deficiency Causes Prostate Neoplasia in the Mouse

(2008) H. B. Pearson et al.   CANCER RESEARCH

LKB1 Deficiency Sensitizes Mice to Carcinogen-Induced Tumorigenesis

(2008) S. Gurumurthy et al.   CANCER RESEARCH

Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I: A Mechanism for the Action of Berberine to Activate AMP-Activated Protein Kinase and Improve Insulin Action

(2008) N. Turner et al.   DIABETES

AMP-activated protein kinase and hypoxic pulmonary vasoconstriction

(2008) Tom P. Robertson et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart

(2008) Edward J. Miller et al.   NATURE