Exosome Drug Delivery through the Blood–Brain Barrier: Experimental Approaches and Potential Applications

Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy

(2018) Tian Tian et al.   BIOMATERIALS

Exosome Mediated Delivery of miR-124 Promotes Neurogenesis after Ischemia

(2017) Jialei Yang et al.   Molecular Therapy-Nucleic Acids

Elucidation of Exosome Migration Across the Blood–Brain Barrier Model In Vitro

(2016) Claire C. Chen et al.   Cellular and Molecular Bioengineering

Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing

(2016) Marie-Cécile Didiot et al.   MOLECULAR THERAPY

From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery

(2016) William A. Banks   NATURE REVIEWS DRUG DISCOVERY

Exosomes: Vehicles of Intercellular Signaling, Biomarkers, and Vectors of Cell Therapy

(2015) Stella Kourembanas   Annual Review of Physiology

Blood–brain barrier endogenous transporters as therapeutic targets: a new model for small molecule CNS drug discovery

(2015) William M Pardridge   EXPERT OPINION ON THERAPEUTIC TARGETS

Exosomes as drug delivery vehicles for Parkinson's disease therapy

(2015) Matthew J. Haney et al.   JOURNAL OF CONTROLLED RELEASE

Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury

(2015) Yanlu Zhang et al.   JOURNAL OF NEUROSURGERY

Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio

(2015) Tianzhi Yang et al.   PHARMACEUTICAL RESEARCH

Exosomes in diagnostic and therapeutic applications: biomarker, vaccine and RNA interference delivery vehicle

(2014) Cecilia Lässer   EXPERT OPINION ON BIOLOGICAL THERAPY

Decreased Amyloid-β Pathologies by Intracerebral Loading of Glycosphingolipid-enriched Exosomes in Alzheimer Model Mice

(2014) Kohei Yuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular vesicles as drug delivery systems: Lessons from the liposome field

(2014) Roy van der Meel et al.   JOURNAL OF CONTROLLED RELEASE

Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice

(2014) J. Mark Cooper et al.   MOVEMENT DISORDERS

Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

(2014) Vladimir P. Torchilin   NATURE REVIEWS DRUG DISCOVERY

Sorting it out: Regulation of exosome loading

(2014) Carolina Villarroya-Beltri et al.   SEMINARS IN CANCER BIOLOGY

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery

(2012) Ronne Wee Yeh Yeo et al.   ADVANCED DRUG DELIVERY REVIEWS

Surface masking shapes the traffic of the neuropeptide Y Y2 receptor

(2012) Michael S. Parker et al.   PEPTIDES

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

(2011) Xiaoying Zhuang et al.   MOLECULAR THERAPY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Focused ultrasound disruption of the blood-brain barrier: a new frontier for therapeutic delivery in molecular neurooncology

(2011) Arnold B. Etame et al.   Neurosurgical Focus

A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes

(2010) Dongmei Sun et al.   MOLECULAR THERAPY

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY