What can molecular pathology contribute to the management of renal cell carcinoma?

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

(2011) Ignacio Varela et al.   NATURE

Molecular Diagnosis and Therapy of Kidney Cancer

(2010) W. Marston Linehan et al.   Annual Review of Medicine

Update on the management of T1 renal cortical tumours

(2010) Mark L. Cutress et al.   BJU INTERNATIONAL

Biology-driven cancer drug development: back to the future

(2010) Christopher J Lord et al.   BMC BIOLOGY

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Signaling pathways in renal cell carcinoma

(2010) Gowrishankar Banumathy et al.   CANCER BIOLOGY & THERAPY

Mechanisms of resistance to imatinib and sunitinib in gastrointestinal stromal tumor

(2010) Wei-Lien Wang et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Histone Methyltransferase Gene SETD2 Is a Novel Tumor Suppressor Gene in Clear Cell Renal Cell Carcinoma

(2010) Gerben Duns et al.   CANCER RESEARCH

Interleukin-8 Mediates Resistance to Antiangiogenic Agent Sunitinib in Renal Cell Carcinoma

(2010) D. Huang et al.   CANCER RESEARCH

Sunitinib Acts Primarily on Tumor Endothelium rather than Tumor Cells to Inhibit the Growth of Renal Cell Carcinoma

(2010) D. Huang et al.   CANCER RESEARCH

WhitherHER2-Related Therapeutics?

(2010) Pradip De et al.   JOURNAL OF CLINICAL ONCOLOGY

Future of Personalized Medicine in Oncology: A Systems Biology Approach

(2010) Ana Maria Gonzalez-Angulo et al.   JOURNAL OF CLINICAL ONCOLOGY

Predictive value of baseline serum vascular endothelial growth factor and neutrophil gelatinase-associated lipocalin in advanced kidney cancer patients receiving sunitinib

(2010) Camillo Porta et al.   KIDNEY INTERNATIONAL

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

(2010) Gillian L. Dalgliesh et al.   NATURE

Diverse somatic mutation patterns and pathway alterations in human cancers

(2010) Zhengyan Kan et al.   NATURE

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

(2010) Shinichi Yachida et al.   NATURE

The genetic basis of kidney cancer: a metabolic disease

(2010) W. Marston Linehan et al.   Nature Reviews Urology

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

Emerging molecular classification in renal cell carcinoma: implications for drug development

(2010) Kathryn E. Hacker et al.   Targeted Oncology

Prognostic and predictive biomarkers in renal cell carcinoma

(2010) Michael M. Vickers et al.   Targeted Oncology

Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets

(2010) Charles Swanton et al.   Genome Medicine

The relevance of a hypoxic tumour microenvironment in prostate cancer

(2009) Grant D. Stewart et al.   BJU INTERNATIONAL

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Molecular Signatures of Localized Clear Cell Renal Cell Carcinoma to Predict Disease-Free Survival after Nephrectomy

(2009) T. Klatte et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Patterns of Gene Expression and Copy-Number Alterations in von-Hippel Lindau Disease-Associated and Sporadic Clear Cell Carcinoma of the Kidney

(2009) R. Beroukhim et al.   CANCER RESEARCH

Systems Biology Reveals New Strategies for Personalizing Cancer Medicine and Confirms the Role of PTEN in Resistance to Trastuzumab

(2009) D. Faratian et al.   CANCER RESEARCH

Diagnostic and Prognostic Molecular Markers for Renal Cell Carcinoma: A Critical Appraisal of the Current State of Research and Clinical Applicability

(2009) Christian Eichelberg et al.   EUROPEAN UROLOGY

Metastatic Renal Cell Carcinoma: Recent Advances in the Targeted Therapy Era

(2009) Giuseppe Di Lorenzo et al.   EUROPEAN UROLOGY

The Expanding Role of Partial Nephrectomy: A Critical Analysis of Indications, Results, and Complications

(2009) Karim Touijer et al.   EUROPEAN UROLOGY

A Critical Analysis of the Actual Role of Minimally Invasive Surgery and Active Surveillance for Kidney Cancer

(2009) Roman Heuer et al.   EUROPEAN UROLOGY

Sorafenib for Treatment of Renal Cell Carcinoma: Final Efficacy and Safety Results of the Phase III Treatment Approaches in Renal Cancer Global Evaluation Trial

(2009) Bernard Escudier et al.   JOURNAL OF CLINICAL ONCOLOGY

Serum Vascular Endothelial Growth Factor and Fibronectin Predict Clinical Response to High-Dose Interleukin-2 Therapy

(2009) Marianna Sabatino et al.   JOURNAL OF CLINICAL ONCOLOGY

From bench to bedside: current and future applications of molecular profiling in renal cell carcinoma

(2009) Androu Arsanious et al.   Molecular Cancer

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

(2009) David A. Barbie et al.   NATURE

Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma

(2009) Etienne Meylan et al.   NATURE

Systems pathology—taking molecular pathology into a new dimension

(2009) Dana Faratian et al.   Nature Reviews Clinical Oncology

The clinical implications of the genetics of renal cell carcinoma

(2009) Inger Rosner et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Mucinous Tubular and Spindle Cell Carcinoma of the Kidney With Sarcomatoid Change

(2008) Jasreman Dhillon et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Differential expression of prognostic markers in histological subtypes of papillary renal cell carcinoma

(2008) Anne Gentil Perret et al.   BJU INTERNATIONAL

Antitumor Activity and Biomarker Analysis of Sunitinib in Patients With Bevacizumab-Refractory Metastatic Renal Cell Carcinoma

(2008) Brian I. Rini et al.   JOURNAL OF CLINICAL ONCOLOGY

von Hippel-Lindau Gene Status and Response to Vascular Endothelial Growth Factor Targeted Therapy for Metastatic Clear Cell Renal Cell Carcinoma

(2008) Toni K. Choueiri et al.   JOURNAL OF UROLOGY

Clinical effect and future considerations for molecularly-targeted therapy in renal cell carcinoma

(2008) Brian I. Rini et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS