Mechanisms of resistance to imatinib and sunitinib in gastrointestinal stromal tumor
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Title
Mechanisms of resistance to imatinib and sunitinib in gastrointestinal stromal tumor
Authors
Keywords
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Journal
CANCER CHEMOTHERAPY AND PHARMACOLOGY
Volume 67, Issue S1, Pages 15-24
Publisher
Springer Nature
Online
2010-12-23
DOI
10.1007/s00280-010-1513-8
References
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Note: Only part of the references are listed.- Rhabdomyosarcomatous Differentiation in Gastrointestinal Stromal Tumors After Tyrosine Kinase Inhibitor Therapy
- (2009) Bernadette Liegl et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Inhibitors of Deacetylases Suppress Oncogenic KIT Signaling, Acetylate HSP90, and Induce Apoptosis in Gastrointestinal Stromal Tumors
- (2009) T. Muhlenberg et al. CANCER RESEARCH
- Resistance to Tyrosine Kinase Inhibitors in Gastrointestinal Stromal Tumors
- (2009) A. W. Gramza et al. CLINICAL CANCER RESEARCH
- Mechanisms of Sunitinib Resistance in Gastrointestinal Stromal Tumors Harboring KITAY502-3ins Mutation: An In vitro Mutagenesis Screen for Drug Resistance
- (2009) T. Guo et al. CLINICAL CANCER RESEARCH
- Insulin-like growth factor 1 receptor expression in wild-type GISTs: A potential novel therapeutic target
- (2009) Maria A. Pantaleo et al. INTERNATIONAL JOURNAL OF CANCER
- Sunitinib-resistant gastrointestinal stromal tumors harbor cis-mutations in the activation loop of the KIT gene
- (2009) Toshirou Nishida et al. International Journal of Clinical Oncology
- Imatinib Plasma Levels Are Correlated With Clinical Benefit in Patients With Unresectable/Metastatic Gastrointestinal Stromal Tumors
- (2009) George D. Demetri et al. JOURNAL OF CLINICAL ONCOLOGY
- T670X KIT Mutations in Gastrointestinal Stromal Tumors: Making Sense of Missense
- (2009) T. Negri et al. JNCI-Journal of the National Cancer Institute
- Gene expression signatures and response to imatinib mesylate in gastrointestinal stromal tumor
- (2009) L. Rink et al. MOLECULAR CANCER THERAPEUTICS
- Inhibition of focal adhesion kinase as a potential therapeutic strategy for imatinib-resistant gastrointestinal stromal tumor
- (2009) K. Sakurama et al. MOLECULAR CANCER THERAPEUTICS
- KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients
- (2009) K. S. Gajiwala et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients
- (2008) C. Braconi et al. ANNALS OF ONCOLOGY
- A Randomized, Phase II Study of Preoperative plus Postoperative Imatinib in GIST: Evidence of Rapid Radiographic Response and Temporal Induction of Tumor Cell Apoptosis
- (2008) John C. McAuliffe et al. ANNALS OF SURGICAL ONCOLOGY
- Molecular Pathobiology of Gastrointestinal Stromal Sarcomas
- (2008) Christopher L. Corless et al. Annual Review of Pathology-Mechanisms of Disease
- Relationship of imatinib-free plasma levels and target genotype with efficacy and tolerability
- (2008) N Widmer et al. BRITISH JOURNAL OF CANCER
- Secondary mutations in the kinase domain of the KIT gene are predominant in imatinib-resistant gastrointestinal stromal tumor
- (2008) Toshirou Nishida et al. CANCER SCIENCE
- Population Pharmacokinetics and Pharmacogenetics of Imatinib in Children and Adults
- (2008) A. Petain et al. CLINICAL CANCER RESEARCH
- Novel V600E BRAF mutations in imatinib-naive and imatinib-resistant gastrointestinal stromal tumors
- (2008) Narasimhan P. Agaram et al. GENES CHROMOSOMES & CANCER
- Long-Term Results From a Randomized Phase II Trial of Standard- Versus Higher-Dose Imatinib Mesylate for Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing KIT
- (2008) Charles D. Blanke et al. JOURNAL OF CLINICAL ONCOLOGY
- Correlation of Kinase Genotype and Clinical Outcome in the North American Intergroup Phase III Trial of Imatinib Mesylate for Treatment of Advanced Gastrointestinal Stromal Tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group
- (2008) Michael C. Heinrich et al. JOURNAL OF CLINICAL ONCOLOGY
- Primary and Secondary Kinase Genotypes Correlate With the Biological and Clinical Activity of Sunitinib in Imatinib-Resistant Gastrointestinal Stromal Tumor
- (2008) Michael C. Heinrich et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase III Randomized, Intergroup Trial Assessing Imatinib Mesylate At Two Dose Levels in Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing the Kit Receptor Tyrosine Kinase: S0033
- (2008) Charles D. Blanke et al. JOURNAL OF CLINICAL ONCOLOGY
- Heterogeneity of kinase inhibitor resistance mechanisms in GIST
- (2008) B Liegl et al. JOURNAL OF PATHOLOGY
- Unlucky number 13? Differential effects of KIT exon 13 mutation in gastrointestinal stromal tumors
- (2008) John C. McAuliffe et al. Molecular Oncology
- Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors
- (2008) C. Tarn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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