A Benzamide-Linked Small Molecule HS-Cf Inhibits TNF-α-Induced Interferon Regulatory Factor-1 in Porcine Chondrocytes: A Potential Disease-Modifying Drug for Osteoarthritis Therapeutics

New takes on treatment and prevention

(2011) David T. Felson   Nature Reviews Rheumatology

Advanced glycation end products cause collagen II reduction by activating Janus kinase/signal transducer and activator of transcription 3 pathway in porcine chondrocytes

(2011) C.-Y. Huang et al.   RHEUMATOLOGY

The role of the cartilage matrix in osteoarthritis

(2010) Dick Heinegård et al.   Nature Reviews Rheumatology

Pharmacologic therapy for osteoarthritis—the era of disease modification

(2010) David J. Hunter   Nature Reviews Rheumatology

Selenomethionine inhibits IL-1β inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX2) expression in primary human chondrocytes

(2010) A.W.M. Cheng et al.   OSTEOARTHRITIS AND CARTILAGE

Chondroprotective effects and mechanisms of resveratrol in advanced glycation end products-stimulated chondrocytes

(2010) Feng-Cheng Liu et al.   ARTHRITIS RESEARCH & THERAPY

Collagen Structure and Stability

(2009) Matthew D. Shoulders et al.   Annual Review of Biochemistry

COX-2 and iNOS are critical in advanced glycation end product-activated chondrocytesin vitro

(2009) C.-Y. Huang et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Suppression of iNOS expression by fucoidan is mediated by regulation of p38 MAPK, JAK/STAT, AP-1 and IRF-1, and depends on up-regulation of scavenger receptor B1 expression in TNF-α- and IFN-γ-stimulated C6 glioma cells☆

(2009) Hang Do et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Obesity, physically demanding work and traumatic knee injury are major risk factors for knee osteoarthritis--a population-based study with a follow-up of 22 years

(2009) A. T. Toivanen et al.   RHEUMATOLOGY

Primary Osteoarthritis No Longer Primary: Three Subsets with Distinct Etiological, Clinical, and Therapeutic Characteristics

(2009) Gabriel Herrero-Beaumont et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming

(2009) Wenlin Li et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Developments in the scientific understanding of osteoarthritis

(2009) Steven B Abramson et al.   ARTHRITIS RESEARCH & THERAPY

The IRF Family Transcription Factors in Immunity and Oncogenesis

(2008) Tomohiko Tamura et al.   Annual Review of Immunology