From Abnormal Hippocampal Synaptic Plasticity in Down Syndrome Mouse Models to Cognitive Disability in Down Syndrome

Memantine Normalizes Several Phenotypic Features in the Ts65Dn Mouse Model of Down Syndrome

(2017) Noemí Rueda et al.   JOURNAL OF ALZHEIMERS DISEASE

A volumetric magnetic resonance imaging study of brain structures in children with Down syndrome

(2014) Joanna Śmigielska-Kuzia et al.   Neurologia i Neurochirurgia Polska

Protein kinase A phosphorylates Down syndrome critical region 1 (RCAN1)

(2012) Seon Sook Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanisms of CaMKII action in long-term potentiation

(2012) John Lisman et al.   NATURE REVIEWS NEUROSCIENCE

Trisomy of the G protein-coupled K+ channel gene, Kcnj6, affects reward mechanisms, cognitive functions, and synaptic plasticity in mice

(2012) A. Cooper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental Enrichment Rescues Postnatal Neurogenesis Defect in the Male and Female Ts65Dn Mouse Model of Down Syndrome

(2011) Lina Chakrabarti et al.   DEVELOPMENTAL NEUROSCIENCE

On the Promise of Pharmacotherapies Targeted at Cognitive and Neurodegenerative Components of Down Syndrome

(2011) Alberto C.S. Costa   DEVELOPMENTAL NEUROSCIENCE

The use of mouse models to understand and improve cognitive deficits in Down syndrome

(2011) I. Das et al.   Disease Models & Mechanisms

Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome

(2011) Tyler K. Best et al.   EXPERIMENTAL NEUROLOGY

Alterations of brain circuits in Down syndrome murine models

(2011) Stefano Gotti et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Rescue of Synaptic Failure and Alleviation of Learning and Memory Impairments in a Trisomic Mouse Model of Down Syndrome

(2011) Julie Blanchard et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

An Increase in Basal BDNF Provokes Hyperactivation of the Akt-Mammalian Target of Rapamycin Pathway and Deregulation of Local Dendritic Translation in a Mouse Model of Down's Syndrome

(2011) J. A. Troca-Marin et al.   JOURNAL OF NEUROSCIENCE

Specific targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice

(2011) J Braudeau et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Exaggerated NMDA mediated LTD in a mouse model of Down syndrome and pharmacological rescuing by memantine

(2011) J. J. Scott-McKean et al.   LEARNING & MEMORY

Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling down syndrome

(2011) Arnaud Duchon et al.   MAMMALIAN GENOME

Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down Syndrome: Activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer

(2011) Mehrdad Faizi et al.   NEUROBIOLOGY OF DISEASE

Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome

(2011) Alexander M. Kleschevnikov et al.   NEUROBIOLOGY OF DISEASE

Trisomy 21 and early brain development

(2011) Tarik F. Haydar et al.   TRENDS IN NEUROSCIENCES

Cranial base, maxillary and mandibular morphology in Down syndrome

(2010) Sunjay Suri et al.   ANGLE ORTHODONTIST

Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome

(2010) Jason Lockrow et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice

(2010) Tao Yu et al.   BRAIN RESEARCH

Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse

(2010) Louisa Dunlevy et al.   CARDIOVASCULAR RESEARCH

Cortical sources of EEG rhythms are abnormal in down syndrome

(2010) Claudio Babiloni et al.   CLINICAL NEUROPHYSIOLOGY

Dendritic Spines: The Stuff That Memories Are Made Of?

(2010) Sonja B. Hofer et al.   CURRENT BIOLOGY

Prevalence of congenital heart defects and persistent pulmonary hypertension of the neonate with Down syndrome

(2010) Michel Emile Weijerman et al.   EUROPEAN JOURNAL OF PEDIATRICS

A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions

(2010) Tao Yu et al.   HUMAN MOLECULAR GENETICS

Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome

(2010) P. Bianchi et al.   JOURNAL OF NEUROSCIENCE

Tumour angiogenesis is reduced in the Tc1 mouse model of Down’s syndrome

(2010) Louise E. Reynolds et al.   NATURE

Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome

(2010) Lina Chakrabarti et al.   NATURE NEUROSCIENCE

Age-related changes in plasma levels of BDNF in Down syndrome patients

(2010) Giada Dogliotti et al.   Immunity & Ageing

The "Down Syndrome Critical Region" Is Sufficient in the Mouse Model to Confer Behavioral, Neurophysiological, and Synaptic Phenotypes Characteristic of Down Syndrome

(2009) N. P. Belichenko et al.   JOURNAL OF NEUROSCIENCE

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1

(2009) Kwan-Hyuck Baek et al.   NATURE

AMPA Receptor Incorporation into Synapses during LTP: The Role of Lateral Movement and Exocytosis

(2009) Hiroshi Makino et al.   NEURON

Evaluation of early stimulation programs for enhancing brain development

(2008) Christine Bonnier   ACTA PAEDIATRICA

Place Cells, Grid Cells, and the Brain's Spatial Representation System

(2008) Edvard I. Moser et al.   Annual Review of Neuroscience

Balancing Structure and Function at Hippocampal Dendritic Spines

(2008) Jennifer N Bourne et al.   Annual Review of Neuroscience

Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of down syndrome

(2008) Pavel V. Belichenko et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome

(2008) E. Morice et al.   LEARNING & MEMORY

Effects of chronic administration of SGS-111 during adulthood and during the pre- and post-natal periods on the cognitive deficits of Ts65Dn mice, a model of Down syndrome

(2007) N RUEDA   BEHAVIOURAL BRAIN RESEARCH

Convergence of entorhinal and CA3 inputs onto pyramidal neurons and interneurons in hippocampal area CA1—An anatomical study in the rat

(2007) Riichi Kajiwara et al.   HIPPOCAMPUS

Synaptic plasticity, memory and the hippocampus: a neural network approach to causality

(2007) Guilherme Neves et al.   NATURE REVIEWS NEUROSCIENCE

Early impairment of synaptic plasticity in patients with Down's syndrome

(2007) Fortunato Battaglia et al.   NEUROBIOLOGY OF AGING

Sleep and EEG features in genetic models of Down syndrome

(2007) Damien Colas et al.   NEUROBIOLOGY OF DISEASE