The challenges and innovations for therapy in children with epilepsy

Rasmussen's encephalitis: clinical features, pathobiology, and treatment advances

(2014) Sophia Varadkar et al.   LANCET NEUROLOGY

Maternal immune activation promotes hippocampal kindling epileptogenesis in mice

(2013) Eduardo Pineda et al.   ANNALS OF NEUROLOGY

The timing of pediatric epilepsy syndromes: What are the developmental triggers?

(2013) Juliann M. Paolicchi   Annals of the New York Academy of Sciences

Migrating partial seizures of infancy: expansion of the electroclinical, radiological and pathological disease spectrum

(2013) Amy McTague et al.   BRAIN

Autism and social cognition in epilepsy

(2013) Roberto Tuchman   CURRENT OPINION IN NEUROLOGY

Clinical spectrum of early onset epileptic encephalopathies caused byKCNQ2mutation

(2013) Mitsuhiro Kato et al.   EPILEPSIA

Long-term functional outcomes and their predictors after hemispherectomy in 115 children

(2013) Ahsan N. V. Moosa et al.   EPILEPSIA

EEG abnormalities as a biomarker for cognitive comorbidities in pharmacoresistant epilepsy

(2013) Gregory L. Holmes   EPILEPSIA

Risk-taking behavior in juvenile myoclonic epilepsy

(2013) Britta Wandschneider et al.   EPILEPSIA

Hypothalamic hamartomas: Optimal approach to clinical evaluation and diagnosis

(2013) Angus A. Wilfong et al.   EPILEPSIA

Stiripentol in Dravet syndrome: Results of a retrospective U.S. study

(2013) Elaine C. Wirrell et al.   EPILEPSIA

Updated ILAE evidence review of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes

(2013) Tracy Glauser et al.   EPILEPSIA

Use of the modified Atkins diet for treatment of refractory childhood epilepsy: A randomized controlled trial

(2013) Suvasini Sharma et al.   EPILEPSIA

Methylphenidate treatment of attention deficit hyperactivity disorder in young people with learning disability and difficult-to-treat epilepsy: Evidence of clinical benefit

(2013) Tangunu Fosi et al.   EPILEPSIA

Maturation-dependent behavioral deficits and cell injury in developing animals during the subacute postictal period

(2013) Lauren M. Mlsna et al.   EPILEPSY & BEHAVIOR

Screening for suicidal ideation in children with epilepsy

(2013) Jana E. Jones et al.   EPILEPSY & BEHAVIOR

Report of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment-resistant epilepsy

(2013) Brenda E. Porter et al.   EPILEPSY & BEHAVIOR

Behavioral impairments in rats with chronic epilepsy suggest comorbidity between epilepsy and attention deficit/hyperactivity disorder

(2013) Eduardo Pineda et al.   EPILEPSY & BEHAVIOR

Vagus nerve stimulation in pediatric patients: Is it really worthwhile?

(2013) Vera C. Terra et al.   EPILEPSY & BEHAVIOR

Disentangling the relationship between epilepsy and its behavioral comorbidities — The need for prospective studies in new-onset epilepsies

(2013) C. Helmstaedter et al.   EPILEPSY & BEHAVIOR

Early epileptic encephalopathies associated with STXBP1 mutations: Could we better delineate the phenotype?

(2013) Giulia Barcia et al.   European Journal of Medical Genetics

Advancing the management of childhood epilepsies

(2013) J. Helen Cross et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Clinical Practice Guidelines and Practice Parameters for the Child Neurologist

(2013) Alan Leviton et al.   JOURNAL OF CHILD NEUROLOGY

How Does the Ketogenic Diet Work? Four Potential Mechanisms

(2013) Nika N. Danial et al.   JOURNAL OF CHILD NEUROLOGY

Risk Factors for Febrile Status Epilepticus: A Case-Control Study

(2013) Dale C. Hesdorffer et al.   JOURNAL OF PEDIATRICS

Prediction of seizure likelihood with a long-term, implanted seizure advisory system in patients with drug-resistant epilepsy: a first-in-man study

(2013) Mark J Cook et al.   LANCET NEUROLOGY

Prevalence of active convulsive epilepsy in sub-Saharan Africa and associated risk factors: cross-sectional and case-control studies

(2013) Anthony K Ngugi et al.   LANCET NEUROLOGY

GRIN2A mutations cause epilepsy-aphasia spectrum disorders

(2013) Gemma L Carvill et al.   NATURE GENETICS

Clinical and genetic aspects of PCDH19-related epilepsy syndromes and the possible role of PCDH19 mutations in males with autism spectrum disorders

(2013) J. J. T. van Harssel et al.   NEUROGENETICS

Evidence-based guideline update: Vagus nerve stimulation for the treatment of epilepsy: Report of the Guideline Development Subcommittee of the American Academy of Neurology

(2013) G. L. Morris et al.   NEUROLOGY

Extending the KCNQ2 encephalopathy spectrum: Clinical and neuroimaging findings in 17 patients

(2013) S. Weckhuysen et al.   NEUROLOGY

Priorities in pediatric epilepsy research: Improving children's futures today

(2013) A. T. Berg et al.   NEUROLOGY

Mortality Risks in New-Onset Childhood Epilepsy

(2013) A. T. Berg et al.   PEDIATRICS

Genotype–phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7.2 potassium channel subunits

(2013) Francesco Miceli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transitional services for adolescents with epilepsy in the UK: A survey

(2013) Anand Iyer et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Efficacy of verapamil as an adjunctive treatment in children with drug-resistant epilepsy: A pilot study

(2013) Francesco Nicita et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment

(2013) Scott C. Baraban et al.   Nature Communications

On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy

(2013) Esther Krook-Magnuson et al.   Nature Communications

Recurrent mutations in theCDKL5gene: Genotype-phenotype relationships

(2012) Nadia Bahi-Buisson et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Epilepsy care guidelines for low- and middle- income countries: From WHO mental health GAP to national programs

(2012) Juri Katchanov et al.   BMC Medicine

A developmental and genetic classification for malformations of cortical development: update 2012

(2012) A. James Barkovich et al.   BRAIN

3.0 T MRI of 2000 consecutive patients with localisation-related epilepsy

(2012) I J Craven et al.   BRITISH JOURNAL OF RADIOLOGY

Targeted treatment trials for tuberous sclerosis and autism: no longer a dream

(2012) Mustafa Sahin   CURRENT OPINION IN NEUROBIOLOGY

The clinical utility of anSCN1Agenetic diagnosis in infantile-onset epilepsy

(2012) ANDREAS BRUNKLAUS et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Autoimmune and inflammatory epilepsies

(2012) Rima Nabbout   EPILEPSIA

A population-based study of newly diagnosed epilepsy in infants

(2012) Christin M. Eltze et al.   EPILEPSIA

The spectrum of anticonvulsant efficacy of retigabine (ezogabine) in animal models: Implications for clinical use

(2012) Charles H. Large et al.   EPILEPSIA

Premature mortality risk in people with convulsive epilepsy: Long follow-up of a cohort in rural China

(2012) Ding Ding et al.   EPILEPSIA

Successful use of fenfluramine as an add-on treatment for Dravet syndrome

(2012) Berten Ceulemans et al.   EPILEPSIA

Early screening and identification of psychological comorbidities in pediatric epilepsy is necessary

(2012) Shanna M. Guilfoyle et al.   EPILEPSY & BEHAVIOR

The reasons for the epilepsy treatment gap in Kilifi, Kenya: Using formative research to identify interventions to improve adherence to antiepileptic drugs

(2012) Julie A. Carter et al.   EPILEPSY & BEHAVIOR

Seizure diaries for clinical research and practice: Limitations and future prospects

(2012) Robert S. Fisher et al.   EPILEPSY & BEHAVIOR

Impaired recruitment of seizure-generated neurons into functional memory networks of the adult dentate gyrus following long-term amygdala kindling

(2012) Neil M. Fournier et al.   EXPERIMENTAL NEUROLOGY

Clinical Observations on Attention-Deficit Hyperactivity Disorder (ADHD) in Children With Frontal Lobe Epilepsy

(2012) Dong-Qing Zhang et al.   JOURNAL OF CHILD NEUROLOGY

Paediatric autoimmune encephalopathies: clinical features, laboratory investigations and outcomes in patients with or without antibodies to known central nervous system autoantigens

(2012) Y. Hacohen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The Neuropsychological and Academic Substrate of New/Recent-Onset Epilepsies

(2012) Daren C. Jackson et al.   JOURNAL OF PEDIATRICS

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Christopher J L Murray et al.   LANCET

De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy

(2012) Giulia Barcia et al.   NATURE GENETICS

Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury

(2012) Jeanne T Paz et al.   NATURE NEUROSCIENCE

Neuronal autoantigens—pathogenesis, associated disorders and antibody testing

(2012) Eric Lancaster et al.   Nature Reviews Neurology

Age at onset of epilepsy, pharmacoresistance, and cognitive outcomes: A prospective cohort study

(2012) A. T. Berg et al.   NEUROLOGY

Bromide in Patients with SCN1A-Mutations Manifesting as Dravet Syndrome

(2012) Jan Lotte et al.   NEUROPEDIATRICS

Seizure control by ketogenic diet-associated medium chain fatty acids

(2012) Pishan Chang et al.   NEUROPHARMACOLOGY

The GABA Excitatory/Inhibitory Shift in Brain Maturation and Neurological Disorders

(2012) Yehezkel Ben-Ari et al.   NEUROSCIENTIST

Transition From Pediatric to Adult Epilepsy Care: A Difficult Process Marked by Medical and Social Crisis

(2012) Peter Camfield et al.   Epilepsy Currents

What We Know and Would Like to Know about CDKL5 and Its Involvement in Epileptic Encephalopathy

(2012) Charlotte Kilstrup-Nielsen et al.   NEURAL PLASTICITY

Comparative effectiveness and implementation research: Directions for Neurology

(2011) Barbara G. Vickrey et al.   ANNALS OF NEUROLOGY

Glucose Transporter 1 Deficiency as a Treatable Cause of Myoclonic Astatic Epilepsy

(2011) Saul A. Mullen   ARCHIVES OF NEUROLOGY

Autoimmune epilepsies

(2011) Sarosh R Irani et al.   CURRENT OPINION IN NEUROLOGY

Elevated VGKC-complex antibodies in a boy with fever-induced refractory epileptic encephalopathy in school-age children (FIRES)

(2011) MARJORIE A ILLINGWORTH et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Depression and epilepsy: A bidirectional relation?

(2011) Andres M. Kanner   EPILEPSIA

Epilepsy, cognition, and behavior: The clinical picture

(2011) Anne T. Berg   EPILEPSIA

Epilepsy as a spectrum disorder: Implications from novel clinical and basic neuroscience

(2011) Frances E. Jensen   EPILEPSIA

Epilepsy imaging study guideline criteria: Commentary on diagnostic testing study guidelines and practice parameters

(2011) William D. Gaillard et al.   EPILEPSIA

Behavior problems in children at time of first recognized seizure and changes over the following 3years

(2011) J.K. Austin et al.   EPILEPSY & BEHAVIOR

GLUT1 deficiency syndrome in clinical practice

(2011) Joerg Klepper   EPILEPSY RESEARCH

Child Neurology Services in Africa

(2011) Jo M. Wilmshurst et al.   JOURNAL OF CHILD NEUROLOGY

Getting to grips with GRADE—perspective from a low-income setting

(2011) Mike English et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Responsive cortical stimulation for the treatment of medically intractable partial epilepsy

(2011) M. J. Morrell et al.   NEUROLOGY

Genotype-phenotype associations in SCN1A-related epilepsies

(2011) S. M. Zuberi et al.   NEUROLOGY

Frequent association of autism spectrum disorder in patients with childhood onset epilepsy

(2010) Muneaki Matsuo et al.   BRAIN & DEVELOPMENT

Paroxysmal disorders in infancy and their risk factors in a population-based cohort: the Generation R Study

(2010) ANNEMARIE M VISSER et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Zebrafish as a model for studying genetic aspects of epilepsy

(2010) G. A. Hortopan et al.   Disease Models & Mechanisms

Frameshift mutations of the ARX gene in familial Ohtahara syndrome

(2010) Mitushiro Kato et al.   EPILEPSIA

What is a classification essay?

(2010) Robert S. Fisher   EPILEPSIA

Estimation of the burden of active and life-time epilepsy: A meta-analytic approach

(2010) Anthony K. Ngugi et al.   EPILEPSIA

Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005-2009

(2010) Anne T. Berg et al.   EPILEPSIA

Cognition, academic achievement, language, and psychopathology in pediatric chronic epilepsy: Short-term outcomes

(2010) Jana E. Jones et al.   EPILEPSY & BEHAVIOR

Development and Implementation of an Adolescent Epilepsy Transition Clinic

(2010) Laura Jurasek et al.   JOURNAL OF NEUROSCIENCE NURSING

Towards a modern classification of the epilepsies?

(2010) Anne T Berg et al.   LANCET NEUROLOGY

Ethosuximide, Valproic Acid, and Lamotrigine in Childhood Absence Epilepsy

(2010) Tracy A. Glauser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Early-onset absence epilepsy caused by mutations in the glucose transporter GLUT1

(2009) Arvid Suls et al.   ANNALS OF NEUROLOGY

Antiepileptic Drug Development in Children

(2009) Catherine Chiron et al.   DRUGS

Guidelines for imaging infants and children with recent-onset epilepsy

(2009) William D. Gaillard et al.   EPILEPSIA

Efficacy, safety, and tolerability of the low glycemic index treatment in pediatric epilepsy

(2009) David A. Muzykewicz et al.   EPILEPSIA

Attention-Deficit Disorders and Epilepsy in Childhood: Incidence, Causative Relations and Treatment Possibilities

(2009) Rami Kaufmann et al.   JOURNAL OF CHILD NEUROLOGY

Our digital world: camera phones and the diagnosis of a seizure

(2009) Steven R Zeiler et al.   LANCET

Convulsing toward the pathophysiology of autism

(2008) Roberto Tuchman et al.   BRAIN & DEVELOPMENT

The epilepsy treatment gap in developing countries: A systematic review of the magnitude, causes, and intervention strategies

(2008) Caroline K. Mbuba et al.   EPILEPSIA

Incidence of Epilepsies and Epileptic Syndromes Among Children in Navarre, Spain: 2002 Through 2005

(2008) Teodoro Durá-Travé et al.   JOURNAL OF CHILD NEUROLOGY

The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial

(2008) Elizabeth G Neal et al.   LANCET NEUROLOGY

Rufinamide for generalized seizures associated with Lennox-Gastaut syndrome

(2008) T. Glauser et al.   NEUROLOGY

Prevalence, incidence and risk factors of epilepsy in older children in rural Kenya

(2008) V. Mung’ala-Odera et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY