Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response

Mechanisms and function of substrate recruitment by F-box proteins

(2013) Jeffrey R. Skaar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The CDK Subunit CKS2 Counteracts CKS1 to Control Cyclin A/CDK2 Activity in Maintaining Replicative Fidelity and Neurodevelopment

(2012) Mattia Frontini et al.   DEVELOPMENTAL CELL

Oligomeric structure of 14-3-3 protein: What do we know about monomers?

(2012) Nikolai N. Sluchanko et al.   FEBS LETTERS

Evolution of signal multiplexing by 14-3-3-binding 2R-ohnologue protein families in the vertebrates

(2012) M. Tinti et al.   Open Biology

The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres

(2012) Mar Carmena et al.   PLOS BIOLOGY

How protein kinases co-ordinate mitosis in animal cells

(2011) Hoi Tang Ma et al.   BIOCHEMICAL JOURNAL

NMR spectroscopy of 14-3-3ζ reveals a flexible C-terminal extension: differentiation of the chaperone and phosphoserine-binding activities of 14-3-3ζ

(2011) Danielle M. Williams et al.   BIOCHEMICAL JOURNAL

Homozygous deficiency of ubiquitin-ligase ring-finger protein RNF168 mimics the radiosensitivity syndrome of ataxia-telangiectasia

(2011) S S Devgan et al.   CELL DEATH AND DIFFERENTIATION

Brainstem Deficiency of the 14-3-3 Regulator of Serotonin Synthesis: A Proteomics Analysis in the Sudden Infant Death Syndrome

(2011) Kevin G. Broadbelt et al.   MOLECULAR & CELLULAR PROTEOMICS

Aurora B and 14-3-3 Coordinately Regulate Clustering of Centralspindlin during Cytokinesis

(2010) Max E. Douglas et al.   CURRENT BIOLOGY

Mitotic Phosphorylation of Cdc25B Ser321Disrupts 14-3-3 Binding to the High Affinity Ser323Site

(2010) Puji Astuti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA damage signaling in response to double-strand breaks during mitosis

(2010) Simona Giunta et al.   JOURNAL OF CELL BIOLOGY

Structure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1

(2010) Mathieu Rappas et al.   NUCLEIC ACIDS RESEARCH

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint

(2010) Marcel A. T. M. van Vugt et al.   PLOS BIOLOGY

Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair

(2009) R. Scott Williams et al.   CELL

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

A Supramodular FHA/BRCT-Repeat Architecture Mediates Nbs1 Adaptor Function in Response to DNA Damage

(2009) Janette Lloyd et al.   CELL

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2

(2009) H Christian Reinhardt et al.   CURRENT OPINION IN CELL BIOLOGY

Plk1-Dependent and -Independent Roles of an ODF2 Splice Variant, hCenexin1, at the Centrosome of Somatic Cells

(2009) Nak-Kyun Soung et al.   DEVELOPMENTAL CELL

14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response

(2009) Duaa H. Mohammad et al.   DNA REPAIR

The decision to enter mitosis: feedback and redundancy in the mitotic entry network

(2009) Arne Lindqvist et al.   JOURNAL OF CELL BIOLOGY

Functional Dynamics of Polo-Like Kinase 1 at the Centrosome

(2009) K. Kishi et al.   MOLECULAR AND CELLULAR BIOLOGY

PALB2 Functionally Connects the Breast Cancer Susceptibility Proteins BRCA1 and BRCA2

(2009) F. Zhang et al.   MOLECULAR CANCER RESEARCH

Structure and Activation Mechanism of the CHK2 DNA Damage Checkpoint Kinase

(2009) Zhenjian Cai et al.   MOLECULAR CELL

Polo-like kinases: conservation and divergence in their functions and regulation

(2009) Vincent Archambault et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Plk1 Activation by Ste20-like Kinase (Slk) Phosphorylation and Polo-Box Phosphopeptide Binding Assayed with the Substrate Translationally Controlled Tumor Protein (TCTP)†

(2008) Tim M. Johnson et al.   BIOCHEMISTRY

GSK-3β Targets Cdc25A for Ubiquitin-Mediated Proteolysis, and GSK-3β Inactivation Correlates with Cdc25A Overproduction in Human Cancers

(2008) Tiebang Kang et al.   CANCER CELL

Inhibition of Polo-like Kinase 1 by Blocking Polo-Box Domain-Dependent Protein-Protein Interactions

(2008) Wolfgang Reindl et al.   CHEMISTRY & BIOLOGY

CDK Inhibitors: Cell Cycle Regulators and Beyond

(2008) Arnaud Besson et al.   DEVELOPMENTAL CELL

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

(2008) J Ross Chapman et al.   EMBO REPORTS

Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin

(2008) Fredrik Melander et al.   JOURNAL OF CELL BIOLOGY

Constitutive phosphorylation of MDC1 physically links the MRE11–RAD50–NBS1 complex to damaged chromatin

(2008) Christoph Spycher et al.   JOURNAL OF CELL BIOLOGY

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

(2008) Andrew Xiao et al.   NATURE

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

(2008) Libor Macůrek et al.   NATURE

The regulated assembly of a PKCɛ complex controls the completion of cytokinesis

(2008) Adrian T. Saurin et al.   NATURE CELL BIOLOGY

Bora and the Kinase Aurora A Cooperatively Activate the Kinase Plk1 and Control Mitotic Entry

(2008) A. Seki et al.   SCIENCE

The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development

(2008) Deborah K. Morrison   TRENDS IN CELL BIOLOGY

Self-regulated mechanism of Plk1 localization to kinetochores: lessons from the Plk1-PBIP1 interaction

(2008) Kyung S Lee et al.   Cell Division