Evolution of signal multiplexing by 14-3-3-binding 2R-ohnologue protein families in the vertebrates

2R and remodeling of vertebrate signal transduction engine

(2011) Lukasz Huminiecki et al.   BMC BIOLOGY

The evolutionary history of the catenin gene family during metazoan evolution

(2011) Zi-Ming Zhao et al.   BMC EVOLUTIONARY BIOLOGY

Mice with AS160/TBC1D4-Thr649Ala Knockin Mutation Are Glucose Intolerant with Reduced Insulin Sensitivity and Altered GLUT4 Trafficking

(2011) Shuai Chen et al.   Cell Metabolism

The evolution of MDM2 family genes

(2011) Jamil Momand et al.   GENE

Brainstem Deficiency of the 14-3-3 Regulator of Serotonin Synthesis: A Proteomics Analysis in the Sudden Infant Death Syndrome

(2011) Kevin G. Broadbelt et al.   MOLECULAR & CELLULAR PROTEOMICS

Visualization and Biochemical Analyses of the Emerging Mammalian 14-3-3-Phosphoproteome

(2011) Catherine Johnson et al.   MOLECULAR & CELLULAR PROTEOMICS

On the Origins of Mendelian Disease Genes in Man: The Impact of Gene Duplication

(2011) J. E. Dickerson et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Evolutionary History of YAP and the Hippo/YAP Pathway

(2011) D. Hilman et al.   MOLECULAR BIOLOGY AND EVOLUTION

Phosphorylation network rewiring by gene duplication

(2011) L. Freschi et al.   Molecular Systems Biology

Gene-Disease Network Analysis Reveals Functional Modules in Mendelian, Complex and Environmental Diseases

(2011) Anna Bauer-Mehren et al.   PLoS One

The capture of phosphoproteins by 14-3-3 proteins mediates actions of insulin

(2011) Shuai Chen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Improving animal phylogenies with genomic data

(2011) Maximilian J. Telford et al.   TRENDS IN GENETICS

A cryptic deletion in 5q31.2 provides further evidence for a minimally deleted region in myelodysplastic syndromes

(2011) Ruth N. MacKinnon et al.   Cancer Genetics

Bioinformatic and experimental survey of 14-3-3-binding sites

(2010) Catherine Johnson et al.   BIOCHEMICAL JOURNAL

ERK/p90RSK/14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicúa

(2010) Kumara Dissanayake et al.   BIOCHEMICAL JOURNAL

Cooperativity within proximal phosphorylation sites is revealed from large-scale proteomics data

(2010) Regev Schweiger et al.   Biology Direct

Advances in the 5q- syndrome

(2010) J. Boultwood et al.   BLOOD

Duplicability of self-interacting human genes

(2010) Asa Perez-Bercoff et al.   BMC EVOLUTIONARY BIOLOGY

Evolution of AANAT: expansion of the gene family in the cephalochordate amphioxus

(2010) Jiri Pavlicek et al.   BMC EVOLUTIONARY BIOLOGY

Systematic analysis, comparison, and integration of disease based human genetic association data and mouse genetic phenotypic information

(2010) Yonqing Zhang et al.   BMC Medical Genomics

14-3-3 Binding Sites in the Snail Protein Are Essential for Snail-Mediated Transcriptional Repression and Epithelial-Mesenchymal Differentiation

(2010) Zhaoyuan Hou et al.   CANCER RESEARCH

A homozygous RAB3GAP2 mutation causes Warburg Micro syndrome

(2010) Guntram Borck et al.   HUMAN GENETICS

Molecular and clinical analysis ofRAF1in Noonan syndrome and related disorders: dephosphorylation of serine 259 as the essential mechanism for mutant activation

(2010) Tomoko Kobayashi et al.   HUMAN MUTATION

Hereditary spastic paraplegia proteins REEP1, spastin, and atlastin-1 coordinate microtubule interactions with the tubular ER network

(2010) Seong H. Park et al.   JOURNAL OF CLINICAL INVESTIGATION

REEP2 Enhances Sweet Receptor Function by Recruitment to Lipid Rafts

(2010) E. Ilegems et al.   JOURNAL OF NEUROSCIENCE

Exercise-induced TBC1D1 Ser237 phosphorylation and 14-3-3 protein binding capacity in human skeletal muscle

(2010) Christian Frøsig et al.   JOURNAL OF PHYSIOLOGY-LONDON

Global Phosphoproteomics Identifies a Major Role for AKT and 14-3-3 in Regulating EDC3

(2010) Mark Larance et al.   MOLECULAR & CELLULAR PROTEOMICS

Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling

(2010) M. Molzan et al.   MOLECULAR AND CELLULAR BIOLOGY

Evolution of Protein Phosphorylation for Distinct Functional Modules in Vertebrate Genomes

(2010) Z. Wang et al.   MOLECULAR BIOLOGY AND EVOLUTION

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

(2010) Georgia Hatzivassiliou et al.   NATURE

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

(2010) Gideon Bollag et al.   NATURE

Phospho.ELM: a database of phosphorylation sites--update 2011

(2010) H. Dinkel et al.   NUCLEIC ACIDS RESEARCH

PLX4032, a selective BRAFV600E kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAFWT melanoma cells

(2010) Ruth Halaban et al.   Pigment Cell & Melanoma Research

Ohnologs in the human genome are dosage balanced and frequently associated with disease

(2010) T. Makino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combining peptide recognition specificity and context information for the prediction of the 14-3-3-mediated interactome in S. cerevisiae and H. sapiens

(2010) Simona Panni et al.   PROTEOMICS

Amphioxus (Branchiostoma floridae) has orthologs of vertebrate odorant receptors

(2009) Allison M Churcher et al.   BMC EVOLUTIONARY BIOLOGY

14-3-3 Binding to Pim-phosphorylated Ser166 and Ser186 of human Mdm2 - Potential interplay with the PKB/Akt pathway and p14ARF

(2009) Nicola T. Wood et al.   FEBS LETTERS

Automated identification of conserved synteny after whole-genome duplication

(2009) J. M. Catchen et al.   GENOME RESEARCH

Loss of REEP4 causes paralysis of the Xenopus embryo

(2009) Joanna Argasinska et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

14-3-3 Protein Masks the DNA Binding Interface of Forkhead Transcription Factor FOXO4

(2009) Jan Silhan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microdeletions including YWHAE in the Miller-Dieker syndrome region on chromosome 17p13.3 result in facial dysmorphisms, growth restriction, and cognitive impairment

(2009) S C Sreenath Nagamani et al.   JOURNAL OF MEDICAL GENETICS

Phylogenetic Analysis of Zebrafish Basic Helix-Loop-Helix Transcription Factors

(2009) Yong Wang et al.   JOURNAL OF MOLECULAR EVOLUTION

Differential 14-3-3 Affinity Capture Reveals New Downstream Targets of Phosphatidylinositol 3-Kinase Signaling

(2009) Fanny Dubois et al.   MOLECULAR & CELLULAR PROTEOMICS

Heterogeneous Patterns of Gene-Expression Diversification in Mammalian Gene Duplicates

(2009) D. Farre et al.   MOLECULAR BIOLOGY AND EVOLUTION

VisANT 3.5: multi-scale network visualization, analysis and inference based on the gene ontology

(2009) Zhenjun Hu et al.   NUCLEIC ACIDS RESEARCH

Nature of the protein universe

(2009) M. Levitt   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Analysis of Cdk1 Substrate Phosphorylation Sites Provides Insights into Evolution

(2009) L. J. Holt et al.   SCIENCE

Comparative Analysis Reveals Conserved Protein Phosphorylation Networks Implicated in Multiple Diseases

(2009) C. S. H. Tan et al.   Science Signaling

Additions, Losses, and Rearrangements on the Evolutionary Route from a Reconstructed Ancestor to the Modern Saccharomyces cerevisiae Genome

(2009) Jonathan L. Gordon et al.   PLoS Genetics

Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators

(2008) Shuai Chen et al.   BIOCHEMICAL JOURNAL

REEP1 mutation spectrum and genotype/phenotype correlation in hereditary spastic paraplegia type 31

(2008) Christian Beetz et al.   BRAIN

Rab proteins and Rab-associated proteins: major actors in the mechanism of protein-trafficking disorders

(2008) Lucien Corbeel et al.   EUROPEAN JOURNAL OF PEDIATRICS

Nucleocytoplasmic Shuttling of the Golgi Phosphatidylinositol 4-Kinase Pik1 Is Regulated by 14-3-3 Proteins and Coordinates Golgi Function with Cell Growth

(2008) Lars Demmel et al.   MOLECULAR BIOLOGY OF THE CELL

The amphioxus genome and the evolution of the chordate karyotype

(2008) Nicholas H. Putnam et al.   NATURE