Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development
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Title
Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development
Authors
Keywords
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Journal
NATURE REVIEWS MICROBIOLOGY
Volume 12, Issue 5, Pages 355-367
Publisher
Springer Nature
Online
2014-04-01
DOI
10.1038/nrmicro3240
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Related references
Note: Only part of the references are listed.- Rapid and Reliable DNA Assembly via Ligase Cycling Reaction
- (2014) Stefan de Kok et al. ACS Synthetic Biology
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- (2013) Lishan Zhao et al. Annual Review of Biochemistry
- Heterologous expression and characterization of bacterial 2-C-methyl-d-erythritol-4-phosphate pathway in Saccharomyces cerevisiae
- (2013) Simon Carlsen et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- A versatile, efficient strategy for assembly of multi-fragment expression vectors in Saccharomyces cerevisiae using 60 bp synthetic recombination sequences
- (2013) Niels GA Kuijpers et al. Microbial Cell Factories
- High-level semi-synthetic production of the potent antimalarial artemisinin
- (2013) C. J. Paddon et al. NATURE
- A molecular marker of artemisinin-resistant Plasmodium falciparum malaria
- (2013) Frédéric Ariey et al. NATURE
- RNA-guided editing of bacterial genomes using CRISPR-Cas systems
- (2013) Wenyan Jiang et al. NATURE BIOTECHNOLOGY
- Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia
- (2013) Olivo Miotto et al. NATURE GENETICS
- Precise and reliable gene expression via standard transcription and translation initiation elements
- (2013) Vivek K Mutalik et al. NATURE METHODS
- Quantitative estimation of activity and quality for collections of functional genetic elements
- (2013) Vivek K Mutalik et al. NATURE METHODS
- The metabolite chemotype ofNicotiana benthamianatransiently expressing artemisinin biosynthetic pathway genes is a function ofCYP71AV1type and relative gene dosage
- (2013) Hieng-Ming Ting et al. NEW PHYTOLOGIST
- Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems
- (2013) James E. DiCarlo et al. NUCLEIC ACIDS RESEARCH
- Amplifying Genetic Logic Gates
- (2013) J. Bonnet et al. SCIENCE
- Synthetic biology: from hype to impact
- (2013) Timothy S. Gardner TRENDS IN BIOTECHNOLOGY
- Metabolic Engineering: Past and Future
- (2013) Benjamin M. Woolston et al. Annual Review of Chemical and Biomolecular Engineering
- Yeast Oligo-Mediated Genome Engineering (YOGE)
- (2013) James E. DiCarlo et al. ACS Synthetic Biology
- Artemisinin-Resistant Malaria: Research Challenges, Opportunities, and Public Health Implications
- (2012) Rick M. Fairhurst et al. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
- Recent progress in the metabolic engineering of alkaloids in plant systems
- (2012) Weslee S Glenn et al. CURRENT OPINION IN BIOTECHNOLOGY
- Two Separate Gene Clusters Encode the Biosynthetic Pathway for the Meroterpenoids Austinol and Dehydroaustinol in Aspergillus nidulans
- (2012) Hsien-Chun Lo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Illuminating the Diversity of Aromatic Polyketide Synthases in Aspergillus nidulans
- (2012) Manmeet Ahuja et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Stabilizing supply of artemisinin and artemisinin-based combination therapy in an era of wide-spread scale-up
- (2012) Rima Shretta et al. MALARIA JOURNAL
- Design, implementation and practice of JBEI-ICE: an open source biological part registry platform and tools
- (2012) T. S. Ham et al. NUCLEIC ACIDS RESEARCH
- Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin
- (2012) P. J. Westfall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia
- (2012) S. Takala-Harrison et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rewritable digital data storage in live cells via engineered control of recombination directionality
- (2012) J. Bonnet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Major Genome Region Underlying Artemisinin Resistance in Malaria
- (2012) I. H. Cheeseman et al. SCIENCE
- Synthetic Biology and Metabolic Engineering
- (2012) Gregory Stephanopoulos ACS Synthetic Biology
- PaR-PaR Laboratory Automation Platform
- (2012) Gregory Linshiz et al. ACS Synthetic Biology
- DeviceEditor visual biological CAD canvas
- (2012) Joanna Chen et al. Journal of Biological Engineering
- Synergies between synthetic biology and metabolic engineering
- (2011) Jens Nielsen et al. NATURE BIOTECHNOLOGY
- A bacterial platform for fermentative production of plant alkaloids
- (2011) Akira Nakagawa et al. Nature Communications
- j5 DNA Assembly Design Automation Software
- (2011) Nathan J. Hillson et al. ACS Synthetic Biology
- The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao)
- (2010) Geoffrey D. Brown MOLECULES
- Erratum: Artemisinin resistance: current status and scenarios for containment
- (2010) Arjen M. Dondorp et al. NATURE REVIEWS MICROBIOLOGY
- Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli
- (2010) P. K. Ajikumar et al. SCIENCE
- A Novel Semi-biosynthetic Route for Artemisinin Production Using Engineered Substrate-Promiscuous P450BM3
- (2009) Jeffrey A. Dietrich et al. ACS Chemical Biology
- Molecular cloning of an aldehyde dehydrogenase implicated in artemisinin biosynthesis in Artemisia annuaThis paper is one of a selection of papers published in a Special Issue from the National Research Council of Canada – Plant Biotechnology Institute.
- (2009) Keat H. Teoh et al. Botany
- Discovery, mechanisms of action and combination therapy of artemisinin
- (2009) Liwang Cui et al. Expert Review of Anti-Infective Therapy
- Impact of the large-scale deployment of artemether/lumefantrine on the malaria disease burden in Africa: case studies of South Africa, Zambia and Ethiopia
- (2009) Karen I Barnes et al. MALARIA JOURNAL
- Programming cells by multiplex genome engineering and accelerated evolution
- (2009) Harris H. Wang et al. NATURE
- Enzymatic assembly of DNA molecules up to several hundred kilobases
- (2009) Daniel G Gibson et al. NATURE METHODS
- High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli
- (2009) Hiroko Tsuruta et al. PLoS One
- Circular Polymerase Extension Cloning of Complex Gene Libraries and Pathways
- (2009) Jiayuan Quan et al. PLoS One
- Maturation of Iron-Sulfur Proteins in Eukaryotes: Mechanisms, Connected Processes, and Diseases
- (2008) Roland Lill et al. Annual Review of Biochemistry
- Application of Functional Genomics to Pathway Optimization for Increased Isoprenoid Production
- (2008) L. Kizer et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Redirection of flux through the FPP branch-point inSaccharomyces cerevisiaeby down-regulating squalene synthase
- (2008) Eric M. Paradise et al. BIOTECHNOLOGY AND BIOENGINEERING
- Developing an industrial artemisinic acid fermentation process to support the cost-effective production of antimalarial artemisinin-based combination therapies
- (2008) Jacob R. Lenihan et al. BIOTECHNOLOGY PROGRESS
- Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid
- (2008) Dae-Kyun Ro et al. BMC BIOTECHNOLOGY
- The Molecular Cloning of Artemisinic Aldehyde Δ11(13) Reductase and Its Role in Glandular Trichome-dependent Biosynthesis of Artemisinin inArtemisia annua
- (2008) Yansheng Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards Taxol (Paclitaxel) production
- (2008) Benedikt Engels et al. METABOLIC ENGINEERING
- Terpenoids: Opportunities for Biosynthesis of Natural Product Drugs Using Engineered Microorganisms
- (2008) Parayil Kumaran Ajikumar et al. MOLECULAR PHARMACEUTICS
- Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae
- (2008) Kristy M Hawkins et al. Nature Chemical Biology
- DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways
- (2008) Zengyi Shao et al. NUCLEIC ACIDS RESEARCH
- Microbial production of plant benzylisoquinoline alkaloids
- (2008) H. Minami et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Qinghaosu (Artemisinin): The Price of Success
- (2008) N. J. White SCIENCE
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