Therapeutic opportunities for manipulating TReg cells in autoimmunity and cancer
Published 2012 View Full Article
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Title
Therapeutic opportunities for manipulating TReg cells in autoimmunity and cancer
Authors
Keywords
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Journal
NATURE REVIEWS DRUG DISCOVERY
Volume 12, Issue 1, Pages 51-63
Publisher
Springer Nature
Online
2012-12-31
DOI
10.1038/nrd3683
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Note: Only part of the references are listed.- Release from Regulatory T Cell-Mediated Suppression during the Onset of Tissue-Specific Autoimmunity Is Associated with Elevated IL-21
- (2014) L. E. Clough et al. JOURNAL OF IMMUNOLOGY
- Extrathymic Generation of Regulatory T Cells in Placental Mammals Mitigates Maternal-Fetal Conflict
- (2012) Robert M. Samstein et al. CELL
- Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut
- (2012) Susan M. Schlenner et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The secret ally: immunostimulation by anticancer drugs
- (2012) Lorenzo Galluzzi et al. NATURE REVIEWS DRUG DISCOVERY
- Oral Immunotherapy for Treatment of Egg Allergy in Children
- (2012) A. Wesley Burks et al. NEW ENGLAND JOURNAL OF MEDICINE
- Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer
- (2012) Ende Zhao et al. OncoImmunology
- Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor
- (2011) Adam T. Waickman et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Rapid Pharmacokinetics of Intradermal Insulin Administered Using Microneedles in Type 1 Diabetes Subjects
- (2011) Jyoti Gupta et al. Diabetes Technology & Therapeutics
- Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope
- (2011) Carolin Daniel et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Regulatory T Cells Require Mammalian Target of Rapamycin Signaling To Maintain Both Homeostasis and Alloantigen-Driven Proliferation in Lymphocyte-Replete Mice
- (2011) Y. Wang et al. JOURNAL OF IMMUNOLOGY
- The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
- (2011) Greg M Delgoffe et al. NATURE IMMUNOLOGY
- Cancer immunotherapy – revisited
- (2011) W. Joost Lesterhuis et al. NATURE REVIEWS DRUG DISCOVERY
- Rapamycin passes the torch: a new generation of mTOR inhibitors
- (2011) Don Benjamin et al. NATURE REVIEWS DRUG DISCOVERY
- Regulatory T-Cell Responses to Low-Dose Interleukin-2 in HCV-Induced Vasculitis
- (2011) David Saadoun et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease
- (2011) John Koreth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse
- (2011) F. Crawford et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD4+Foxp3+ Regulatory T-cell Impairment by Paclitaxel is Independent of Toll-like Receptor 4
- (2011) Y. Zhu et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- T cell receptor recognition of self and foreign antigens in the induction of autoimmunity
- (2011) Kai W. Wucherpfennig et al. SEMINARS IN IMMUNOLOGY
- Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses
- (2010) Li-Fan Lu et al. CELL
- Frequency of Circulating Tregs with Demethylated FOXP3 Intron 1 in Melanoma Patients Receiving Tumor Vaccines and Potentially Treg-Depleting Agents
- (2010) I. J. M. de Vries et al. CLINICAL CANCER RESEARCH
- Dendritic Cell Vaccination in Combination with Anti-CD25 Monoclonal Antibody Treatment: A Phase I/II Study in Metastatic Melanoma Patients
- (2010) J. F. M. Jacobs et al. CLINICAL CANCER RESEARCH
- Human regulatory T cells in autoimmune diseases
- (2010) Gregory L Cvetanovich et al. CURRENT OPINION IN IMMUNOLOGY
- The Mammalian Target of Rapamycin: Linking T Cell Differentiation, Function, and Metabolism
- (2010) Jonathan D. Powell et al. IMMUNITY
- Immunotherapy of Type 1 Diabetes: Where Are We and Where Should We Be Going?
- (2010) Xunrong Luo et al. IMMUNITY
- Prediction and Pathogenesis in Type 1 Diabetes
- (2010) Anette-G. Ziegler et al. IMMUNITY
- Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells
- (2010) Yohsuke Harada et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
- (2010) Rachel A. Gottschalk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors: Figure 1.
- (2010) Matthias Merkenschlager et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A Decrease of Regulatory T Cells Correlates With Overall Survival After Sunitinib-based Antiangiogenic Therapy in Metastatic Renal Cancer Patients
- (2010) Olivier Adotevi et al. JOURNAL OF IMMUNOTHERAPY
- Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
- (2010) Ye Zheng et al. NATURE
- Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells
- (2010) Weiming Ouyang et al. NATURE IMMUNOLOGY
- The S1P1-mTOR axis directs the reciprocal differentiation of TH1 and Treg cells
- (2010) Guangwei Liu et al. NATURE IMMUNOLOGY
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- (2010) Sean P Sullivan et al. NATURE MEDICINE
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- (2010) Volker Brinkmann et al. NATURE REVIEWS DRUG DISCOVERY
- Enhancement of antigen-specific Treg vaccination in vivo
- (2010) C. Daniel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register
- (2010) B. D. Stadinski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stability of the Regulatory T Cell Lineage in Vivo
- (2010) Y. P. Rubtsov et al. SCIENCE
- Clinical Use of Anti-CD25 Antibody Daclizumab to Enhance Immune Responses to Tumor Antigen Vaccination by Targeting Regulatory T cells
- (2009) Andrew J. Rech et al. Annals of the New York Academy of Sciences
- Regulatory Lymphocytes and Intestinal Inflammation
- (2009) Ana Izcue et al. Annual Review of Immunology
- Pre-treatment with chemotherapy can enhance the antigenicity and immunogenicity of tumours by promoting adaptive immune responses
- (2009) W M Liu et al. BRITISH JOURNAL OF CANCER
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- (2009) H. Xin et al. CANCER RESEARCH
- MicroRNA Control in the Immune System: Basic Principles
- (2009) Changchun Xiao et al. CELL
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- (2009) Gilles Marodon et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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- (2009) Qingguo Ruan et al. IMMUNITY
- Control of Regulatory T Cell Lineage Commitment and Maintenance
- (2009) Steven Z. Josefowicz et al. IMMUNITY
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- (2009) Makoto Miyara et al. IMMUNITY
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- (2009) Kylie E. Webster et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2009) Karl S. Peggs et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2009) J. Hou et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: TCR Stimulation Is Sufficient for Induction of Foxp3 Expression in the Absence of DNA Methyltransferase 1
- (2009) S. Z. Josefowicz et al. JOURNAL OF IMMUNOLOGY
- The receptor S1P1 overrides regulatory T cell–mediated immune suppression through Akt-mTOR
- (2009) Guangwei Liu et al. NATURE IMMUNOLOGY
- The cunning little vixen: Foxo and the cycle of life and death
- (2009) Stephen M Hedrick NATURE IMMUNOLOGY
- An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a
- (2009) Peter J R Ebert et al. NATURE IMMUNOLOGY
- Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic molecules
- (2009) David Marsolais et al. NATURE REVIEWS DRUG DISCOVERY
- Infectious tolerance via the consumption of essential amino acids and mTOR signaling
- (2009) S. P. Cobbold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TGF-β: A Master of All T Cell Trades
- (2008) Ming O. Li et al. CELL
- Inducible reprogramming of human T cells into Treg cells by a conditionally active form of FOXP3
- (2008) Sarah E. Allan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Forced overexpression of either of the two common human Foxp3 isoforms can induce regulatory T cells from CD4+CD25– cells
- (2008) Tineke Aarts-Riemens et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- DNA methylation controls Foxp3 gene expression
- (2008) Julia K. Polansky et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Mucosal Insulin Vaccination for Type 1 Diabetes Prevention
- (2008) E. Bonifacio et al. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
- Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire
- (2008) Matthew A. Burchill et al. IMMUNITY
- The anticancer immune response: indispensable for therapeutic success?
- (2008) Laurence Zitvogel et al. JOURNAL OF CLINICAL INVESTIGATION
- The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease
- (2008) Mark M.W. Chong et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The AKT–mTOR axis regulates de novo differentiation of CD4+Foxp3+cells
- (2008) Sokol Haxhinasto et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Dicer-dependent microRNA pathway safeguards regulatory T cell function
- (2008) Adrian Liston et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial
- (2008) Kirsti Näntö-Salonen et al. LANCET
- "Inside-Out" Signaling of Sphingosine-1-Phosphate: Therapeutic Targets
- (2008) K. Takabe et al. PHARMACOLOGICAL REVIEWS
- Induction of antigen-specific regulatory T cells in wild-type mice: Visualization and targets of suppression
- (2008) P. Verginis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
- (2008) S. Sauer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulatory T Cells: Mechanisms of Differentiation and Function
- (2007) Steven Z. Josefowicz et al. Annual Review of Immunology
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