Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity
出版年份 2014 全文链接
标题
Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity
作者
关键词
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出版物
NATURE MEDICINE
Volume 20, Issue 12, Pages 1427-1435
出版商
Springer Nature
发表日期
2014-11-25
DOI
10.1038/nm.3735
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Is Required for Insulin Signaling and Is Implicated in Hepatic Insulin Resistance
- (2014) E. Tubbs et al. DIABETES
- Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance
- (2013) Marc Schneeberger et al. CELL
- Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease
- (2013) Karima Begriche et al. HEPATOLOGY
- Autophagosomes form at ER–mitochondria contact sites
- (2013) Maho Hamasaki et al. NATURE
- Calcium Signaling through CaMKII Regulates Hepatic Glucose Production in Fasting and Obesity
- (2012) Lale Ozcan et al. Cell Metabolism
- Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver
- (2012) T. Otoda et al. DIABETES
- Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
- (2012) Estela Area-Gomez et al. EMBO JOURNAL
- An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers
- (2012) Theresa R. Bomfim et al. JOURNAL OF CLINICAL INVESTIGATION
- Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes
- (2012) Yiguo Wang et al. NATURE
- Endoplasmic reticulum–mitochondria contacts: function of the junction
- (2012) Ashley A. Rowland et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondria as sensors and regulators of calcium signalling
- (2012) Rosario Rizzuto et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis
- (2012) D. Sebastian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of Endoplasmic Reticulum Stress in Metabolic Disease and Other Disorders
- (2011) Lale Ozcan et al. Annual Review of Medicine
- Urban planning of the endoplasmic reticulum (ER): How diverse mechanisms segregate the many functions of the ER
- (2011) Emily M. Lynes et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Sodium Phenylbutyrate, a Drug With Known Capacity to Reduce Endoplasmic Reticulum Stress, Partially Alleviates Lipid-Induced Insulin Resistance and β-Cell Dysfunction in Humans
- (2011) Changting Xiao et al. DIABETES
- Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress
- (2011) R. Bravo et al. JOURNAL OF CELL SCIENCE
- Mitochondrial Fission Contributes to Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle
- (2011) H.-F. Jheng et al. MOLECULAR AND CELLULAR BIOLOGY
- Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
- (2011) Suneng Fu et al. NATURE
- Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
- (2011) Joshua M. Baughman et al. NATURE
- A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
- (2011) Diego De Stefani et al. NATURE
- ER Tubules Mark Sites of Mitochondrial Division
- (2011) J. R. Friedman et al. SCIENCE
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria
- (2010) César Cárdenas et al. CELL
- Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
- (2010) Gökhan S. Hotamisligil CELL
- Tauroursodeoxycholic Acid May Improve Liver and Muscle but Not Adipose Tissue Insulin Sensitivity in Obese Men and Women
- (2010) Marleen Kars et al. DIABETES
- The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes
- (2010) Mary-Elizabeth Patti et al. ENDOCRINE REVIEWS
- Prevalence and Trends in Obesity Among US Adults, 1999-2008
- (2010) Katherine M. Flegal JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Effects of a high-fat diet on energy metabolism and ROS production in rat liver
- (2010) Guillaume Vial et al. JOURNAL OF HEPATOLOGY
- Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface
- (2010) György Csordás et al. MOLECULAR CELL
- Ca2+ transfer from the ER to mitochondria: When, how and why
- (2009) Rosario Rizzuto et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response
- (2009) Sebastian Schuck et al. JOURNAL OF CELL BIOLOGY
- GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis
- (2009) Renata Sano et al. MOLECULAR CELL
- Foxo1 integrates insulin signaling with mitochondrial function in the liver
- (2009) Zhiyong Cheng et al. NATURE MEDICINE
- Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells
- (2009) Mariusz R Wieckowski et al. Nature Protocols
- Role of Mitochondrial Dysfunction in Insulin Resistance
- (2008) Jeong-a Kim et al. CIRCULATION RESEARCH
- Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss
- (2008) M. F. Gregor et al. DIABETES
- Increase in Endoplasmic Reticulum Stress-Related Proteins and Genes in Adipose Tissue of Obese, Insulin-Resistant Individuals
- (2008) G. Boden et al. DIABETES
- Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases
- (2008) Sudheer K. Mantena et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitofusin 2 tethers endoplasmic reticulum to mitochondria
- (2008) Olga Martins de Brito et al. NATURE
- Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis
- (2008) P Pinton et al. ONCOGENE
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