A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production

miR-17-92 Cluster Targets Phosphatase and Tensin Homology and Ikaros Family Zinc Finger 4 to Promote TH17-mediated Inflammation

(2014) Si-Qi Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Suppressor of Cytokine Signaling 1 in Helper T Cells Leads to Defective Th17 Differentiation by Enhancing Antagonistic Effects of IFN-  on STAT3 and Smads

(2014) K. Tanaka et al.   JOURNAL OF IMMUNOLOGY

Epigenetics in Immune-Mediated Pulmonary Diseases

(2013) Yu Liu et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Regulation of miRNA biogenesis and turnover in the immune system

(2013) Yelena Bronevetsky et al.   IMMUNOLOGICAL REVIEWS

mir-17-92: a polycistronic oncomir with pleiotropic functions

(2013) Virginie Olive et al.   IMMUNOLOGICAL REVIEWS

MicroRNA-155 is essential for TH2-mediated allergen-induced eosinophilic inflammation in the lung

(2013) Carina Malmhäll et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire

(2013) Yelena Bronevetsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

microRNA-17-92 Regulates IL-10 Production by Regulatory T Cells and Control of Experimental Autoimmune Encephalomyelitis

(2013) D. de Kouchkovsky et al.   JOURNAL OF IMMUNOLOGY

The microRNA cluster miR-17∼92 promotes TFH cell differentiation and represses subset-inappropriate gene expression

(2013) Dirk Baumjohann et al.   NATURE IMMUNOLOGY

MicroRNAs of the miR-17∼92 family are critical regulators of TFH differentiation

(2013) Seung Goo Kang et al.   NATURE IMMUNOLOGY

The transcriptional landscape of αβ T cell differentiation

(2013) Michael Mingueneau et al.   NATURE IMMUNOLOGY

Dupilumab in Persistent Asthma with Elevated Eosinophil Levels

(2013) Sally Wenzel et al.   NEW ENGLAND JOURNAL OF MEDICINE

A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis

(2013) Virginie Olive et al.   eLife

Role of Inositol Poly-Phosphatases and Their Targets in T Cell Biology

(2013) Neetu Srivastava et al.   Frontiers in Immunology

Airway Epithelial miRNA Expression Is Altered in Asthma

(2012) Owen D. Solberg et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Antagonism of mmu-mir-106a attenuates asthma features in allergic murine model

(2012) Amit Sharma et al.   JOURNAL OF APPLIED PHYSIOLOGY

Integrin α9β1 in airway smooth muscle suppresses exaggerated airway narrowing

(2012) Chun Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Asthma phenotypes: the evolution from clinical to molecular approaches

(2012) Sally E Wenzel   NATURE MEDICINE

A miR-19 regulon that controls NF-κB signaling

(2012) Michael P. Gantier et al.   NUCLEIC ACIDS RESEARCH

Suppressors of Cytokine Signaling (SOCS) Proteins and JAK/STAT Pathways

(2011) Taiga Tamiya et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation

(2011) S. Jiang et al.   BLOOD

MicroRNA-29 Regulates T-Box Transcription Factors and Interferon-γ Production in Helper T Cells

(2011) David F. Steiner et al.   IMMUNITY

Human asthma phenotypes: from the clinic, to cytokines, and back again

(2011) Nirav R. Bhakta et al.   IMMUNOLOGICAL REVIEWS

Inhibition of house dust mite–induced allergic airways disease by antagonism of microRNA-145 is comparable to glucocorticoid treatment

(2011) Adam Collison et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Let-7 microRNA–mediated regulation of IL-13 and allergic airway inflammation

(2011) Manish Kumar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lebrikizumab Treatment in Adults with Asthma

(2011) Jonathan Corren et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microfluidic-Based Multiplex qRT-PCR Identifies Diagnostic and Prognostic microRNA Signatures in the Sera of Prostate Cancer Patients

(2010) Felix Moltzahn et al.   CANCER RESEARCH

Asthma and Allergic Inflammation

(2010) Richard M. Locksley   CELL

Proinflammatory Role forlet-7MicroRNAS in Experimental Asthma

(2010) Sumanth Polikepahad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia

(2010) Konstantinos J. Mavrakis et al.   NATURE CELL BIOLOGY

miRTarBase: a database curates experimentally validated microRNA–target interactions

(2010) Sheng-Da Hsu et al.   NUCLEIC ACIDS RESEARCH

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Antagonism of microRNA-126 suppresses the effector function of TH2 cells and the development of allergic airways disease

(2009) J. Mattes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppressors of cytokine signaling (SOCS) in T cell differentiation, maturation, and function

(2009) Douglas C. Palmer et al.   TRENDS IN IMMUNOLOGY

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY

T cell antigen receptor stimulation induces MALT1 paracaspase–mediated cleavage of the NF-κB inhibitor A20

(2008) Beatrice Coornaert et al.   NATURE IMMUNOLOGY

Targeting the NF-κB pathway in asthma and chronic obstructive pulmonary disease

(2008) Michael R. Edwards et al.   PHARMACOLOGY & THERAPEUTICS