Regulation of miRNA biogenesis and turnover in the immune system

T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire

(2013) Yelena Bronevetsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Eri1 regulates microRNA homeostasis and mouse lymphocyte development and antiviral function

(2012) M. F. Thomas et al.   BLOOD

Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies

(2012) Z. Y. Xu-Monette et al.   BLOOD

MicroRNAs in Stress Signaling and Human Disease

(2012) Joshua T. Mendell et al.   CELL

Roles for MicroRNAs in Conferring Robustness to Biological Processes

(2012) Margaret S. Ebert et al.   CELL

c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells

(2012) Zuqin Nie et al.   CELL

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

(2012) Charles Y. Lin et al.   CELL

Degradation of Host MicroRNAs by Poxvirus Poly(A) Polymerase Reveals Terminal RNA Methylation as a Protective Antiviral Mechanism

(2012) Simone Backes et al.   Cell Host & Microbe

Smad-mediated regulation of microRNA biosynthesis

(2012) Matthew T. Blahna et al.   FEBS LETTERS

The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling

(2012) J. Chen et al.   GENES & DEVELOPMENT

Quantitative functions of Argonaute proteins in mammalian development

(2012) D. Wang et al.   GENES & DEVELOPMENT

KSRP: A checkpoint for inflammatory cytokine production in astrocytes

(2012) Xuelin Li et al.   GLIA

MicroRNAs, new effectors and regulators of NF-κB

(2012) Mark P. Boldin et al.   IMMUNOLOGICAL REVIEWS

The interplay between endoplasmic reticulum stress and inflammation

(2012) Sumaira Z Hasnain et al.   IMMUNOLOGY AND CELL BIOLOGY

Inhibition of MicroRNA-302 (miR-302) by Bone Morphogenetic Protein 4 (BMP4) Facilitates the BMP Signaling Pathway

(2012) Hara Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-146acontrols the resolution of T cell responses in mice

(2012) Lili Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dynamic MicroRNA Gene Transcription and Processing during T Cell Development

(2012) F. F. Kirigin et al.   JOURNAL OF IMMUNOLOGY

miR-29ab1 Deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias That Is Dysregulated in Multiple Sclerosis

(2012) K. M. Smith et al.   JOURNAL OF IMMUNOLOGY

Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay

(2012) Kai P Hoefig et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function

(2012) Inga Loedige et al.   NUCLEIC ACIDS RESEARCH

Lin28b Reprograms Adult Bone Marrow Hematopoietic Progenitors to Mediate Fetal-Like Lymphopoiesis

(2012) Joan Yuan et al.   SCIENCE

IRE1  Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2

(2012) J.-P. Upton et al.   SCIENCE

Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation

(2012) Hao-Ming Chang et al.   Nature Communications

Degradation of Cellular miR-27 by a Novel, Highly Abundant Viral Transcript Is Important for Efficient Virus Replication In Vivo

(2012) Lisa Marcinowski et al.   PLoS Pathogens

The influence of sex and gender on the immune response

(2011) Sabine Oertelt-Prigione   AUTOIMMUNITY REVIEWS

Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation

(2011) S. Jiang et al.   BLOOD

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

(2011) A. Montecalvo et al.   BLOOD

Blood Cell Origin of Circulating MicroRNAs: A Cautionary Note for Cancer Biomarker Studies

(2011) C. C. Pritchard et al.   Cancer Prevention Research

Limiting Ago protein restricts RNAi and microRNA biogenesis during early development in Xenopus laevis

(2011) E. Lund et al.   GENES & DEVELOPMENT

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

(2011) Ruoning Wang et al.   IMMUNITY

MicroRNA-29 Regulates T-Box Transcription Factors and Interferon-γ Production in Helper T Cells

(2011) David F. Steiner et al.   IMMUNITY

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Germline deletion of the miR-17∼92 cluster causes skeletal and growth defects in humans

(2011) Loïc de Pontual et al.   NATURE GENETICS

The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ

(2011) Feng Ma et al.   NATURE IMMUNOLOGY

MicroRNAs in body fluids—the mix of hormones and biomarkers

(2011) Maria Angelica Cortez et al.   Nature Reviews Clinical Oncology

Murine cytomegalovirus encodes a miR-27 inhibitor disguised as a target

(2011) V. Libri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia

(2011) E. Moussay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NF- B dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies

(2011) J. L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Parsimonious Model for Gene Regulation by miRNAs

(2011) S. Djuranovic et al.   SCIENCE

Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity

(2011) Nicolas Léveillé et al.   Nature Communications

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia

(2010) Ulf Klein et al.   CANCER CELL

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

(2010) Li-Fan Lu et al.   CELL

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

(2010) Markus Hafner et al.   CELL

Circulating microRNAs: Association with disease and potential use as biomarkers

(2010) Glen Reid et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Transcriptional regulation of mammalian miRNA genes

(2010) Brian C. Schanen et al.   GENOMICS

Regulation of MicroRNA Expression and Abundance during Lymphopoiesis

(2010) Stefan Kuchen et al.   IMMUNITY

Cellular and molecular basis for the regulation of inflammation by TGF- 

(2010) A. Yoshimura et al.   JOURNAL OF BIOCHEMISTRY

Smad Proteins Bind a Conserved RNA Sequence to Promote MicroRNA Maturation by Drosha

(2010) Brandi N. Davis et al.   MOLECULAR CELL

Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration

(2010) Yujing Zhang et al.   MOLECULAR CELL

Phosphorylation of human Argonaute proteins affects small RNA binding

(2010) Sabine Rüdel et al.   NUCLEIC ACIDS RESEARCH

Down-Regulation of a Host MicroRNA by a Herpesvirus saimiri Noncoding RNA

(2010) D. Cazalla et al.   SCIENCE

Target RNA-Directed Trimming and Tailing of Small Silencing RNAs

(2010) S. L. Ameres et al.   SCIENCE

MicroRNA Control in the Immune System: Basic Principles

(2009) Changchun Xiao et al.   CELL

TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA Uridylation

(2009) Inha Heo et al.   CELL

Regulation of MicroRNA Biogenesis: A miRiad of mechanisms

(2009) Brandi N Davis et al.   Cell Communication and Signaling

Dicer1 functions as a haploinsufficient tumor suppressor

(2009) M. S. Kumar et al.   GENES & DEVELOPMENT

HuR recruits let-7/RISC to repress c-Myc expression

(2009) H. H. Kim et al.   GENES & DEVELOPMENT

Chromatin poises miRNA- and protein-coding genes for expression

(2009) A. Barski et al.   GENOME RESEARCH

RETRACTED: Maturation of MicroRNA Is Hormonally Regulated by a Nuclear Receptor

(2009) Kaoru Yamagata et al.   MOLECULAR CELL

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

(2009) Michele Trabucchi et al.   NATURE

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

Silencing by small RNAs is linked to endosomal trafficking

(2009) Young Sik Lee et al.   NATURE CELL BIOLOGY

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

(2009) Derrick J. Gibbings et al.   NATURE CELL BIOLOGY

The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2

(2009) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

(2009) T.-C. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals

(2009) F. Bazzoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies

(2008) Yan Zeng et al.   BIOCHEMICAL JOURNAL

The c-myb proto-oncogene and microRNA-15a comprise an active autoregulatory feedback loop in human hematopoietic cells

(2008) H. Zhao et al.   BLOOD

Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma

(2008) Charles H. Lawrie et al.   BRITISH JOURNAL OF HAEMATOLOGY

Nuclear functions of heterogeneous nuclear ribonucleoproteins A/B

(2008) Yaowu He et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MicroRNAs grow up in the immune system

(2008) Kai P Hoefig et al.   CURRENT OPINION IN IMMUNOLOGY

Argonaute-2 Expression Is Regulated by Epidermal Growth Factor Receptor and Mitogen-Activated Protein Kinase Signaling and Correlates with a Transformed Phenotype in Breast Cancer Cells

(2008) Brian D. Adams et al.   ENDOCRINOLOGY

Chromatin structure analyses identify miRNA promoters

(2008) F. Ozsolak et al.   GENES & DEVELOPMENT

Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells

(2008) Rajini Mudhasani et al.   JOURNAL OF CELL BIOLOGY

The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease

(2008) Mark M.W. Chong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops

(2008) Gracjan Michlewski et al.   MOLECULAR CELL

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

Prolyl 4-hydroxylation regulates Argonaute 2 stability

(2008) Hank H. Qi et al.   NATURE

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

(2008) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY

The evolution of our thinking about microRNAs

(2008) Victor Ambros   NATURE MEDICINE

Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing

(2008) K Mark Ansel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The exonuclease ERI-1 has a conserved dual role in 5.8S rRNA processing and RNAi

(2008) Harrison W Gabel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

miR-29 miRNAs activate p53 by targeting p85α and CDC42

(2008) Seong-Yeon Park et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing

(2008) A. Azuma-Mukai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A regulatory interplay between miR-27a and Runx1 during megakaryopoiesis

(2008) O. Ben-Ami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Blockade of MicroRNA Processing by Lin28

(2008) S. R. Viswanathan et al.   SCIENCE

Degradation of microRNAs by a Family of Exoribonucleases in Arabidopsis

(2008) Vanitharani Ramachandran et al.   SCIENCE