The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells

Dynamic regulation of Bcl6 in follicular helper CD4 T (Tfh) cells

(2013) Youn Soo Choi et al.   CURRENT OPINION IN IMMUNOLOGY

Itch expression by Treg cells controls Th2 inflammatory responses

(2013) Hyung-seung Jin et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: STAT1 Is Required for IL-6-Mediated Bcl6 Induction for Early Follicular Helper Cell Differentiation

(2013) Y. S. Choi et al.   JOURNAL OF IMMUNOLOGY

Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility

(2013) Heping Xu et al.   NATURE

The microRNA cluster miR-17∼92 promotes TFH cell differentiation and represses subset-inappropriate gene expression

(2013) Dirk Baumjohann et al.   NATURE IMMUNOLOGY

MicroRNAs of the miR-17∼92 family are critical regulators of TFH differentiation

(2013) Seung Goo Kang et al.   NATURE IMMUNOLOGY

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation

(2012) André Ballesteros-Tato et al.   IMMUNITY

STAT5 is a potent negative regulator of TFHcell differentiation

(2012) Robert J. Johnston et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1

(2012) Alex Karnowski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bcl6 and Maf Cooperate To Instruct Human Follicular Helper CD4 T Cell Differentiation

(2012) M. A. Kroenke et al.   JOURNAL OF IMMUNOLOGY

Novel Foxo1-dependent transcriptional programs control Treg cell function

(2012) Weiming Ouyang et al.   NATURE

Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile

(2012) Kenneth J Oestreich et al.   NATURE IMMUNOLOGY

Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation

(2012) N. Bollig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Regulation of FOXO protein stability via ubiquitination and proteasome degradation

(2011) Haojie Huang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

How T Cells Earn the Follicular Rite of Passage

(2011) Carola G. Vinuesa et al.   IMMUNITY

ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6

(2011) Youn Soo Choi et al.   IMMUNITY

Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity

(2011) Hong-Erh Liang et al.   NATURE IMMUNOLOGY

The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells

(2011) Wataru Ise et al.   NATURE IMMUNOLOGY

IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation

(2011) Danelle Eto et al.   PLoS One

Late Interleukin-6 Escalates T Follicular Helper Cell Responses and Controls a Chronic Viral Infection

(2011) J. A. Harker et al.   SCIENCE

K33-Linked Polyubiquitination of T Cell Receptor-ζ Regulates Proteolysis-Independent T Cell Signaling

(2010) Haining Huang et al.   IMMUNITY

Foxo Transcription Factors Control Regulatory T Cell Development and Function

(2010) Yann M. Kerdiles et al.   IMMUNITY

Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells

(2010) Yohsuke Harada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Germinal Center T Follicular Helper Cell IL-4 Production Is Dependent on Signaling Lymphocytic Activation Molecule Receptor (CD150)

(2010) I. Yusuf et al.   JOURNAL OF IMMUNOLOGY

Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells

(2010) Weiming Ouyang et al.   NATURE IMMUNOLOGY

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor

(2009) Yann M Kerdiles et al.   NATURE IMMUNOLOGY

Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase

(2009) M. Gigoux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE

A Fundamental Role for Interleukin-21 in the Generation of T Follicular Helper Cells

(2008) Alexis Vogelzang et al.   IMMUNITY

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages

(2008) Roza I. Nurieva et al.   IMMUNITY

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

(2008) Aurelie T Bauquet et al.   NATURE IMMUNOLOGY