Squalene hopene cyclases are protonases for stereoselective Brønsted acid catalysis

Entropy is Key to the Formation of Pentacyclic Terpenoids by Enzyme-Catalyzed Polycyclization

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New Generation of Biocatalysts for Organic Synthesis

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Enantioselective Intramolecular CH Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo

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Synthesis of Heterocyclic Terpenoids by Promiscuous Squalene-Hopene Cyclases

(2013) Miriam Seitz et al.   CHEMBIOCHEM

Squalene hopene cyclases: highly promiscuous and evolvable catalysts for stereoselective CC and CX bond formation

(2013) Stephan C Hammer et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Biocatalytic retrosynthesis

(2013) Nicholas J Turner et al.   Nature Chemical Biology

Cytochrome P450-catalyzed insertion of carbenoids into N–H bonds

(2013) Z. Jane Wang et al.   Chemical Science

Prokaryotic squalene-hopene cyclases can be converted to citronellal cyclases by single amino acid exchange

(2012) Gabriele Siedenburg et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Current developments and challenges in the search for a naturally selected Diels-Alderase

(2012) Hak Joong Kim et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Substrate specificity of a novel squalene-hopene cyclase from Zymomonas mobilis

(2012) Miriam Seitz et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Terpenoid synthase structures: a so far incomplete view of complex catalysis

(2012) Yang Gao et al.   NATURAL PRODUCT REPORTS

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes

(2012) P. S. Coelho et al.   SCIENCE

Biotinylated Rh(III) Complexes in Engineered Streptavidin for Accelerated Asymmetric C-H Activation

(2012) T. K. Hyster et al.   SCIENCE

Stereoselective Friedel–Crafts alkylation catalyzed by squalene hopene cyclases

(2012) Stephan C. Hammer et al.   TETRAHEDRON

Modulating the Acidity: Highly Acidic Brønsted Acids in Asymmetric Catalysis

(2011) Magnus Rueping et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Activation-Independent Cyclization of Monoterpenoids

(2011) Gabriele Siedenburg et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Super Brønsted acid catalysis

(2011) Cheol Hong Cheon et al.   CHEMICAL COMMUNICATIONS

Cytochrome P450: taming a wild type enzyme

(2011) Sang Taek Jung et al.   CURRENT OPINION IN BIOTECHNOLOGY

Chemo-enzymatic syntheses of drimane-type sesquiterpenes and the fundamental core of hongoquercin meroterpenoid by recombinant squalene–hopene cyclase

(2011) Yukie Yonemura et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Combinatorial reshaping of the Candida antarctica lipase A substrate pocket for enantioselectivity using an extremely condensed library

(2011) A. G. Sandstrom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

What makes an enzyme promiscuous?

(2010) Ann Babtie et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Attractive noncovalent interactions in asymmetric catalysis: Links between enzymes and small molecule catalysts

(2010) R. R. Knowles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

(2010) J. B. Siegel et al.   SCIENCE

Asymmetric Brønsted acid catalysis in aqueous solution

(2010) Magnus Rueping et al.   Chemical Science

Biocatalytic Friedel-Crafts Alkylation Using Non-natural Cofactors

(2009) Harald Stecher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Directed evolution drives the next generation of biocatalysts

(2009) Nicholas J Turner   Nature Chemical Biology

The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria

(2009) U. Metzger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Dynamism and Evolvability

(2009) N. Tokuriki et al.   SCIENCE

Zeolite NaY‐Promoted Monocyclization of Epoxy Polyene Terpenes: A Unique Route for the Direct Synthesis of Incompletely Cyclized Naturally Occurring Terpenols

(2008) Constantinos Tsangarakis et al.   ADVANCED SYNTHESIS & CATALYSIS

Binaphthol-derived phosphoric acid as a versatile catalyst for enantioselective carbon–carbon bond forming reactions

(2008) Masahiro Terada   CHEMICAL COMMUNICATIONS

Biomimetic Chemistry: Biology as an Inspiration

(2008) Ronald Breslow   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid and Enantioselective Synthetic Approaches to Germanicol and Other Pentacyclic Triterpenes

(2008) Karavadhi Surendra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY