A homing system targets therapeutic T cells to brain cancer

Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges

(2018) Dai Fukumura et al.   Nature Reviews Clinical Oncology

CAR-T cells: the long and winding road to solid tumors

(2018) Maria Michela D’Aloia et al.   Cell Death & Disease

T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy

(2017) Robert Sackstein et al.   LABORATORY INVESTIGATION

CD6 as a potential target for treating multiple sclerosis

(2017) Yan Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticulate Tetrac Inhibits Growth and Vascularity of Glioblastoma Xenografts

(2017) Thangirala Sudha et al.   Hormones & Cancer

HER2-Specific Chimeric Antigen Receptor–Modified Virus-Specific T Cells for Progressive Glioblastoma

(2017) Nabil Ahmed et al.   JAMA Oncology

T cell activation and differentiation is modulated by a CD6 domain 1 antibody Itolizumab

(2017) Usha Bughani et al.   PLoS One

Homing to solid cancers: a vascular checkpoint in adoptive cell therapy using CAR T-cells

(2016) Ann Ager et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

CD6 as a Cell Surface Receptor and As a Target for Regulating Immune Responses

(2016) Marion H. Brown   CURRENT DRUG TARGETS

Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape

(2016) Meenakshi Hegde et al.   JOURNAL OF CLINICAL INVESTIGATION

CD6 modulates thymocyte selection and peripheral T cell homeostasis

(2016) Marc Orta-Mascaró et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Adoptive T-cell therapy for cancer: The era of engineered T cells

(2015) Chiara Bonini et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

Structures of CD6 and Its Ligand CD166 Give Insight into Their Interaction

(2015) Paul E. Chappell et al.   STRUCTURE

ALCAM/CD166 Is a TGF- -Responsive Marker and Functional Regulator of Prostate Cancer Metastasis to Bone

(2014) A. G. Hansen et al.   CANCER RESEARCH

Regulation of Immune Cell Infiltration into the CNS by Regional Neural Inputs Explained by the Gate Theory

(2013) Yasunobu Arima et al.   MEDIATORS OF INFLAMMATION

FAK promotes recruitment of talin to nascent adhesions to control cell motility

(2012) Christine Lawson et al.   JOURNAL OF CELL BIOLOGY

Proteomic Analysis of Endothelial Lipid Rafts Reveals a Novel Role of Statins in Antioxidation

(2012) Ming-Xia Gu et al.   JOURNAL OF PROTEOME RESEARCH

Mechanisms of Leukocyte Transendothelial Migration

(2011) William A. Muller   Annual Review of Pathology-Mechanisms of Disease

CD166/Activated leukocyte cell adhesion molecule is expressed on glioblastoma progenitor cells and involved in the regulation of tumor cell invasion

(2011) N. Kijima et al.   NEURO-ONCOLOGY

Rolling Cell Adhesion

(2010) Rodger P. McEver et al.   Annual Review of Cell and Developmental Biology

HER2-Specific T Cells Target Primary Glioblastoma Stem Cells and Induce Regression of Autologous Experimental Tumors

(2010) N. Ahmed et al.   CLINICAL CANCER RESEARCH

Differential Roles for Endothelial ICAM-1, ICAM-2, and VCAM-1 in Shear-Resistant T Cell Arrest, Polarization, and Directed Crawling on Blood-Brain Barrier Endothelium

(2010) O. Steiner et al.   JOURNAL OF IMMUNOLOGY

Impaired Orthotopic Glioma Growth and Vascularization in Transgenic Mouse Models of Alzheimer's Disease

(2010) D. Paris et al.   JOURNAL OF NEUROSCIENCE

TGF-β Increases Glioma-Initiating Cell Self-Renewal through the Induction of LIF in Human Glioblastoma

(2009) Silvia Peñuelas et al.   CANCER CELL

Lymphocyte transmigration in the brain: a new way of thinking

(2008) Boris P-L Lee et al.   NATURE IMMUNOLOGY