Microbial biosynthesis of medicinally important plant secondary metabolites

Regioselective synthesis of flavonoid bisglycosides using Escherichia coli harboring two glycosyltransferases

(2013) Hyeon Jeong Kim et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Regiospecific modifications of naringenin for astragalin production inEscherichia coli

(2013) Sailesh Malla et al.   BIOTECHNOLOGY AND BIOENGINEERING

Optimization of amorphadiene synthesis inbacillus subtilisvia transcriptional, translational, and media modulation

(2013) Kang Zhou et al.   BIOTECHNOLOGY AND BIOENGINEERING

Metabolic engineering of Saccharomyces cerevisiae for production of ginsenosides

(2013) Zhubo Dai et al.   METABOLIC ENGINEERING

High-level semi-synthetic production of the potent antimalarial artemisinin

(2013) C. J. Paddon et al.   NATURE

Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs

(2013) Dokyun Na et al.   NATURE BIOTECHNOLOGY

Production of Bioactive Flavonol Rhamnosides by Expression of Plant Genes in Escherichia coli

(2012) Bong-Gyu Kim et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Construction of a fusion flagellin complex and evaluation of the protective immunity of it in red snapper (Lutjanus sanguineus)

(2012) H.Y. Liang et al.   LETTERS IN APPLIED MICROBIOLOGY

Metabolic engineering of the flavone-C-glycoside pathway using polyprotein technology

(2012) Melissa Brazier-Hicks et al.   METABOLIC ENGINEERING

Metabolic engineering of Escherichia coli for (2S)-pinocembrin production from glucose by a modular metabolic strategy

(2012) Junjun Wu et al.   METABOLIC ENGINEERING

De novo production of the flavonoid naringenin in engineered Saccharomyces cerevisiae

(2012) Frank Koopman et al.   Microbial Cell Factories

Systems metabolic engineering of microorganisms for natural and non-natural chemicals

(2012) Jeong Wook Lee et al.   Nature Chemical Biology

Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin

(2012) P. J. Westfall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Production of 7-O-Methyl Aromadendrin, a Medicinally Valuable Flavonoid, in Escherichia coli

(2011) Sailesh Malla et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Optimization of Rhamnetin Production in Escherichia coli

(2011) Su Hyun Sung   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Enhanced Flavonoid Production in Streptomyces venezuelae via Metabolic Engineering

(2011) Sung Ryeol Park   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Genome-scale metabolic network modeling results in minimal interventions that cooperatively force carbon flux towards malonyl-CoA

(2011) Peng Xu et al.   METABOLIC ENGINEERING

A bacterial platform for fermentative production of plant alkaloids

(2011) Akira Nakagawa et al.   Nature Communications

Considerable Increase in Resveratrol Production by Recombinant Industrial Yeast Strains with Use of Rich Medium

(2010) T. Sydor et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

In Silico Identification of Gene Amplification Targets for Improvement of Lycopene Production

(2010) H. S. Choi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biosynthesis of Plant-Specific Flavones and Flavonols in Streptomyces venezuelae

(2010) Sung Ryeol Park   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

(2010) M. Komatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli

(2010) P. K. Ajikumar et al.   SCIENCE

OptForce: An Optimization Procedure for Identifying All Genetic Manipulations Leading to Targeted Overproductions

(2010) Sridhar Ranganathan et al.   PLoS Computational Biology

Improved Squalene Production via Modulation of the Methylerythritol 4-Phosphate Pathway and Heterologous Expression of Genes from Streptomyces peucetius ATCC 27952 in Escherichia coli

(2009) G. P. Ghimire et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Novel approaches and achievements in biosynthesis of functional isoprenoids in Escherichia coli

(2009) Hisashi Harada et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Molecular characterization of flavonol synthase from poplar and its application to the synthesis of 3-O-methylkaempferol

(2009) Bong-Gyu Kim et al.   BIOTECHNOLOGY LETTERS

Combinatorial biosynthesis of plant medicinal polyketides by microorganisms

(2009) Sueharu Horinouchi   CURRENT OPINION IN CHEMICAL BIOLOGY

Engineering of plant-specific phenylpropanoids biosynthesis in Streptomyces venezuelae

(2009) Sung Ryeol Park et al.   JOURNAL OF BIOTECHNOLOGY

Metabolic engineering of the complete pathway leading to heterologous biosynthesis of various flavonoids and stilbenoids in Saccharomyces cerevisiae

(2009) Emmanouil Trantas et al.   METABOLIC ENGINEERING

Yeast artificial chromosomes employed for random assembly of biosynthetic pathways and production of diverse compounds in Saccharomyces cerevisiae

(2009) Michael Naesby et al.   Microbial Cell Factories

Synthetic protein scaffolds provide modular control over metabolic flux

(2009) John E Dueber et al.   NATURE BIOTECHNOLOGY

High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli

(2009) Hiroko Tsuruta et al.   PLoS One

Developing an industrial artemisinic acid fermentation process to support the cost-effective production of antimalarial artemisinin-based combination therapies

(2008) Jacob R. Lenihan et al.   BIOTECHNOLOGY PROGRESS

Metabolic engineering for plant natural product biosynthesis in microbes

(2008) Joseph A Chemler et al.   CURRENT OPINION IN BIOTECHNOLOGY

Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards Taxol (Paclitaxel) production

(2008) Benedikt Engels et al.   METABOLIC ENGINEERING

Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene

(2008) Jennifer R. Anthony et al.   METABOLIC ENGINEERING

Terpenoids: Opportunities for Biosynthesis of Natural Product Drugs Using Engineered Microorganisms

(2008) Parayil Kumaran Ajikumar et al.   MOLECULAR PHARMACEUTICS

Strain Improvement of RecombinantEscherichia colifor Efficient Production of Plant Flavonoids

(2008) Effendi Leonard et al.   MOLECULAR PHARMACEUTICS

Microbial production of plant benzylisoquinoline alkaloids

(2008) H. Minami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Botanical drugs: Challenges and opportunities

(2007) Yixuan Liu et al.   LIFE SCIENCES