A Bifunctional Anti-Amyloid Blocks Oxidative Stress and the Accumulation of Intraneuronal Amyloid-Beta

The Anti-Amyloid-β and Neuroprotective Properties of a Novel Tricyclic Pyrone Molecule

(2017) Izumi Maezawa et al.   JOURNAL OF ALZHEIMERS DISEASE

Oligomerization Alters Binding Affinity between Amyloid Beta and a Modulator of Peptide Aggregation

(2017) Silvia Hilt et al.   Journal of Physical Chemistry C

Plaque formation and the intraneuronal accumulation of β-amyloid in Alzheimer's disease

(2017) Reisuke H. Takahashi et al.   PATHOLOGY INTERNATIONAL

Amyloid-β as a Modulator of Synaptic Plasticity

(2017) Mordhwaj S. Parihar et al.   JOURNAL OF ALZHEIMERS DISEASE

Anticancer potential of diarylidenyl piperidone derivatives, HO-4200 and H-4318, in cisplatin resistant primary ovarian cancer

(2016) Adam C. ElNaggar et al.   CANCER BIOLOGY & THERAPY

Protective spin-labeled fluorenes maintain amyloid beta peptide in small oligomers and limit transitions in secondary structure

(2015) Robin Altman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Nitroxide pharmaceutical development for age-related degeneration and disease

(2015) Jacob A. Zarling et al.   Frontiers in Genetics

Transient dynamics of Aβ contribute to toxicity in Alzheimer’s disease

(2014) E. Hubin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Oxidative Stress in Alzheimer’s Disease: Why Did Antioxidant Therapy Fail?

(2014) Torbjörn Persson et al.   Oxidative Medicine and Cellular Longevity

An efficient synthesis of 3-(N-piperidinemethyl)-2,2,5,5-tetramethyl-1-oxy-3-pyrroline, a promising radioprotector for cancer radiotherapy

(2014) Haitao Wu et al.   TETRAHEDRON LETTERS

Alzheimer´s Disease and Oxidative Stress: A Review

(2013) Miroslav Pohanka   CURRENT MEDICINAL CHEMISTRY

Oxidative Stress in Alzheimer’s Disease: Are We Connecting the Dots?

(2013) Michela Rosini et al.   JOURNAL OF MEDICINAL CHEMISTRY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

The Influence of Spin-Labeled Fluorene Compounds on the Assembly and Toxicity of the Aβ Peptide

(2012) Jitka Petrlova et al.   PLoS One

Amyloid-β Peptide Binds to Cytochrome C Oxidase Subunit 1

(2012) Luis Fernando Hernandez-Zimbron et al.   PLoS One

Conserved features of intermediates in amyloid assembly determine their benign or toxic states

(2012) R. Krishnan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis and study of 2-amino-7-bromofluorenes modified with nitroxides and their precursors as dual anti-amyloid and antioxidant active compounds

(2011) Tamás Kálai et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of N-Substituted 3,5-Bis(arylidene)-4-piperidones with High Antitumor and Antioxidant Activity

(2011) Tamás Kálai et al.   JOURNAL OF MEDICINAL CHEMISTRY

Oxidative Stress in the Progression of Alzheimer Disease in the Frontal Cortex

(2010) Mubeen A. Ansari et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression

(2010) Melissa A. Bradley et al.   NEUROBIOLOGY OF AGING

Exogenous Antioxidants—Double-Edged Swords in Cellular Redox State: Health Beneficial Effects at Physiologic Doses versus Deleterious Effects at High Doses

(2010) Jaouad Bouayed et al.   Oxidative Medicine and Cellular Longevity

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

(2010) H. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial permeability transition pore in Alzheimer's disease: Cyclophilin D and amyloid beta

(2009) Heng Du et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

(2009) Paula I. Moreira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Aβ-mediated ROS production by Cu ions: Structural insights, mechanisms and relevance to Alzheimer's disease

(2009) Christelle Hureau et al.   BIOCHIMIE

Hydrogen Peroxide Promotes Aβ Production through JNK-dependent Activation of γ-Secretase

(2008) Chengyong Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Candidate anti-Aβ fluorene compounds selected from analogs of amyloid imaging agents

(2008) Hyun-Seok Hong et al.   NEUROBIOLOGY OF AGING

Nitroxides are more efficient inhibitors of oxidative damage to calf skin collagen than antioxidant vitamins

(2007) Elisabetta Venditti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS