Sinulariolide Induced Hepatocellular Carcinoma Apoptosis through Activation of Mitochondrial-Related Apoptotic and PERK/eIF2α/ATF4/CHOP Pathway

AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts

(2013) Diana M. González-Gironès et al.   APOPTOSIS

Targeting the Apoptosis Pathway in Prostate Cancer

(2013) Robert R. Zielinski et al.   CANCER JOURNAL

Enhanced levels of the apoptotic BAX/BCL-2 ratio in children with acute lymphoblastic leukemia and high-risk features

(2013) Maria Kaparou et al.   GENETICS AND MOLECULAR BIOLOGY

Upregulation of Phosphorylated HSP27, PRDX2, GRP75, GRP78 and GRP94 in Acquired Middle Ear Cholesteatoma Growth

(2013) Kuen Ho et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

5-Episinuleptolide Acetate, a Norcembranoidal Diterpene from the Formosan Soft Coral Sinularia sp., Induces Leukemia Cell Apoptosis through Hsp90 Inhibition

(2013) Kao-Jean Huang et al.   MOLECULES

Calreticulin, an endoplasmic reticulum-resident protein, is highly expressed and essential for cell proliferation and migration in oral squamous cell carcinoma

(2013) Wei-Fan Chiang et al.   ORAL ONCOLOGY

Gene regulatory network of unfolded protein response genes in endoplasmic reticulum stress

(2012) Sayuri Takayanagi et al.   CELL STRESS & CHAPERONES

Proteomic investigation of anti-tumor activities exerted by sinularin against A2058 melanoma cells

(2012) Tzu-Rong Su et al.   ELECTROPHORESIS

Proteomic profiling of the 11-dehydrosinulariolide-treated oral carcinoma cells Ca9–22: Effects on the cell apoptosis through mitochondrial-related and ER stress pathway

(2012) Chih-I Liu et al.   Journal of Proteomics

Induction of Apoptosis by Sinulariolide from Soft Coral through Mitochondrial-Related and p38MAPK Pathways on Human Bladder Carcinoma Cells

(2012) Choo-Aun Neoh et al.   Marine Drugs

Induction of Apoptosis by 11-Dehydrosinulariolide via Mitochondrial Dysregulation and ER Stress Pathways in Human Melanoma Cells

(2012) Tzu-Rong Su et al.   Marine Drugs

An Investigation into the Cytotoxic Effects of 13-Acetoxysarcocrassolide from the Soft Coral Sarcophyton crassocaule on Bladder Cancer Cells

(2011) Ching-Chyuan Su et al.   Marine Drugs

Oxygenated Cembranoids from the Cultured and Wild-Type Soft Corals Sinularia flexibilis

(2009) Jui-Hsin Su et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Rodent models of diabetic cardiomyopathy

(2009) H. Bugger et al.   Disease Models & Mechanisms

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY