5-Episinuleptolide Acetate, a Norcembranoidal Diterpene from the Formosan Soft Coral Sinularia sp., Induces Leukemia Cell Apoptosis through Hsp90 Inhibition

Diterpenoids from the Soft Coral Sinularia maxima and Their Inhibitory Effects on Lipopolysaccharide-Stimulated Production of Pro-inflammatory Cytokines in Bone Marrow-Derived Dendritic Cells

(2015) Nguyen Phuong Thao et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Anti-inflammatory norditerpenoids from the soft coral Sinularia maxima

(2012) Nguyen Phuong Thao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Proteomic profiling of the 11-dehydrosinulariolide-treated oral carcinoma cells Ca9–22: Effects on the cell apoptosis through mitochondrial-related and ER stress pathway

(2012) Chih-I Liu et al.   Journal of Proteomics

Sinularones A–I, New Cyclopentenone and Butenolide Derivatives from a Marine Soft Coral Sinularia sp. and Their Antifouling Activity

(2012) Haiyan Shi et al.   Marine Drugs

New Cembrane Diterpenoids from a Hainan Soft Coral Sinularia sp.

(2012) Bin Yang et al.   Marine Drugs

Induction of Apoptosis by 11-Dehydrosinulariolide via Mitochondrial Dysregulation and ER Stress Pathways in Human Melanoma Cells

(2012) Tzu-Rong Su et al.   Marine Drugs

A Great Barrier Reef Sinularia sp. Yields Two New Cytotoxic Diterpenes

(2012) Anthony D. Wright et al.   Marine Drugs

Norcembranoidal Diterpenes from a Formosan Soft Coral Sinularia sp.

(2012) Wei-Hsuan Yen et al.   MOLECULES

Terpenoids of Sinularia soft corals: chemistry and bioactivity

(2012) Wen-ting Chen et al.   Acta Pharmaceutica Sinica B

Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers

(2011) Komal Jhaveri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

HSP90 Inhibition Is Effective in Breast Cancer: A Phase II Trial of Tanespimycin (17-AAG) Plus Trastuzumab in Patients with HER2-Positive Metastatic Breast Cancer Progressing on Trastuzumab

(2011) S. Modi et al.   CLINICAL CANCER RESEARCH

Novel macrocyclic and polycyclic norcembranoid diterpenes from Sinularia species of soft coral: Structural relationships and biosynthetic speculations

(2011) Yi Li et al.   NATURAL PRODUCT REPORTS

Neuroprotection by marine-derived compound, 11-dehydrosinulariolide, in an in vitro Parkinson’s model: a promising candidate for the treatment of Parkinson’s disease

(2011) Wu-Fu Chen et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Chloroscabrolides, chlorinated norcembranoids from the Indonesian soft coral Sinularia sp.

(2011) Ernesto Fattorusso et al.   TETRAHEDRON

New developments in Hsp90 inhibitors as anti-cancer therapeutics: Mechanisms, clinical perspective and more potential

(2009) Yanyan Li et al.   DRUG RESISTANCE UPDATES

Discovery and development of heat shock protein 90 inhibitors

(2008) Tony Taldone et al.   BIOORGANIC & MEDICINAL CHEMISTRY