Fructus Gardenia Extract Ameliorates Oxonate-Induced Hyperuricemia with Renal Dysfunction in Mice by Regulating Organic Ion Transporters and mOIT3

Renal Transport of Uric Acid: Evolving Concepts and Uncertainties

(2012) Ion Alexandru Bobulescu et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Pharmacological and pathophysiological roles of carnitine/organic cation transporters (OCTNs: SLC22A4, SLC22A5 and Slc22a21)

(2012) Ikumi Tamai   BIOPHARMACEUTICS & DRUG DISPOSITION

The uric acid metabolism pathway as a therapeutic target in hyperuricemia related to metabolic syndrome

(2012) Andréa Name Colado Simão et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

OIT3 deficiency impairs uric acid reabsorption in renal tubule

(2012) Bing Yan et al.   FEBS LETTERS

Regulation of renal organic anion and cation transporters by thymoquinone in cisplatin induced kidney injury

(2012) Ramazan Ulu et al.   FOOD AND CHEMICAL TOXICOLOGY

Uricosuric and nephroprotective properties of Ramulus Mori ethanol extract in hyperuricemic mice

(2012) Yun-Wei Shi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Renal Uptake of Substrates for Organic Anion Transporters Oat1 and Oat3 and Organic Cation Transporters Oct1 and Oct2 is Altered in Rats with Adenine-Induced Chronic Renal Failure

(2012) Hiroki Komazawa et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Drug transport by Organic Anion Transporters (OATs)

(2012) Gerhard Burckhardt   PHARMACOLOGY & THERAPEUTICS

Protective Effect of Crocetin on Hemorrhagic Shock–Induced Acute Renal Failure in Rats

(2012) Yunbo Wang et al.   SHOCK

Hyperuricemia, gout and the kidney

(2011) Terence Gibson   CURRENT OPINION IN RHEUMATOLOGY

Quercetin regulates organic ion transporter and uromodulin expression and improves renal function in hyperuricemic mice

(2011) Qing-Hua Hu et al.   EUROPEAN JOURNAL OF NUTRITION

Protective effects of cortex fraxini coumarines against oxonate-induced hyperuricemia and renal dysfunction in mice

(2011) Jian-Mei Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Increased Protein Level of URAT1 was Observed in Obesity/Metabolic Syndrome Model Mice

(2011) Masaru Doshi et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

ABCG2 is a High-Capacity Urate Transporter and its Genetic Impairment Increases Serum Uric Acid Levels in Humans

(2011) Akiyoshi Nakayama et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Organic Cation Transporter 2 Mediates Cisplatin-Induced Oto- and Nephrotoxicity and Is a Target for Protective Interventions

(2010) Giuliano Ciarimboli et al.   AMERICAN JOURNAL OF PATHOLOGY

Identification and functional characterization of uric acid transporter Urat1 (Slc22a12) in rats

(2010) Masanobu Sato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Simiao pill ameliorates urate underexcretion and renal dysfunction in hyperuricemic mice

(2010) Qing-Hua Hu et al.   JOURNAL OF ETHNOPHARMACOLOGY

A Benefit-Risk Assessment of Benzbromarone in the Treatment of Gout

(2009) Ming-Han H Lee et al.   DRUG SAFETY

Homozygous SLC2A9 Mutations Cause Severe Renal Hypouricemia

(2009) D. Dinour et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

(2008) Veronique Vitart et al.   NATURE GENETICS

Multiple organic anion transporters contribute to net renal excretion of uric acid

(2008) Satish A. Eraly et al.   PHYSIOLOGICAL GENOMICS

Renal xenobiotic transporters are differentially expressed in mice following cisplatin treatment

(2008) Lauren M. Aleksunes et al.   TOXICOLOGY