Resveratrol and its major sulfated conjugates are substrates of organic anion transporting polypeptides (OATPs): Impact on growth of ZR-75-1 breast cancer cells

Interplay between metabolism and transport of resveratrol

(2013) Alexandra Maier-Salamon et al.   Annals of the New York Academy of Sciences

Absorption of resveratrol by vascular endothelial cells through passive diffusion and an SGLT1-mediated pathway

(2013) Ming-liang Chen et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death

(2013) Virginie Aires et al.   MOLECULAR NUTRITION & FOOD RESEARCH

One-year supplementation with a grape extract containing resveratrol modulates inflammatory-related microRNAs and cytokines expression in peripheral blood mononuclear cells of type 2 diabetes and hypertensive patients with coronary artery disease

(2013) João Tomé-Carneiro et al.   PHARMACOLOGICAL RESEARCH

Sulfate Metabolites Provide an Intracellular Pool for Resveratrol Generation and Induce Autophagy with Senescence

(2013) K. R. Patel et al.   Science Translational Medicine

Resveratrol and its metabolites inhibit pro-inflammatory effects of lipopolysaccharides in U-937 macrophages in plasma-representative concentrations

(2013) Jessica Walker et al.   Food & Function

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1

(2013) Anne T Nies et al.   Genome Medicine

Carrier-mediated transport of quercetin conjugates: Involvement of organic anion transporters and organic anion transporting polypeptides

(2012) Chi Chun Wong et al.   BIOCHEMICAL PHARMACOLOGY

Transport, stability, and biological activity of resveratrol

(2011) Dominique Delmas et al.   Annals of the New York Academy of Sciences

The Expression and Function of Organic Anion Transporting Polypeptides in Normal Tissues and in Cancer

(2011) Amanda Obaidat et al.   Annual Review of Pharmacology and Toxicology

Flavonoid conjugates interact with organic anion transporters (OATs) and attenuate cytotoxicity of adefovir mediated by organic anion transporter 1 (OAT1/SLC22A6)

(2011) Chi Chun Wong et al.   BIOCHEMICAL PHARMACOLOGY

Organic Anion Transporting Polypeptides (OATPs): Regulation of Expression and Function

(2011) Martin Svoboda et al.   CURRENT DRUG METABOLISM

Hepatic Glucuronidation of Resveratrol: Interspecies Comparison of Enzyme Kinetic Profiles in Human, Mouse, Rat, and Dog

(2011) Alexandra Maier-Salamon et al.   Drug Metabolism and Pharmacokinetics

Resveratrol Metabolites Do Not Elicit Early Pro-apoptotic Mechanisms in Neuroblastoma Cells

(2011) Jason D. Kenealey et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Role of membrane dynamics processes and exogenous molecules in cellular resveratrol uptake: Consequences in bioavailability and activities

(2011) Dominique Delmas et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Drug Resistance and Cellular Adaptation to Tumor Acidic pH Microenvironment

(2011) Jonathan W. Wojtkowiak et al.   MOLECULAR PHARMACEUTICS

Pleiotropic mechanisms facilitated by resveratrol and its metabolites

(2010) Barbara Calamini et al.   BIOCHEMICAL JOURNAL

Altered expression of organic anion transporter polypeptide (OATP) genes in human breast carcinoma

(2010) Katrin Wlcek et al.   CANCER BIOLOGY & THERAPY

Repeat Dose Study of the Cancer Chemopreventive Agent Resveratrol in Healthy Volunteers: Safety, Pharmacokinetics, and Effect on the Insulin-like Growth Factor Axis

(2010) V. A. Brown et al.   CANCER RESEARCH

Clinical Pharmacology of Resveratrol and Its Metabolites in Colorectal Cancer Patients

(2010) K. R. Patel et al.   CANCER RESEARCH

Selective Synthesis and Biological Evaluation of Sulfate-Conjugated Resveratrol Metabolites

(2010) Juma Hoshino et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters

(2009) Simone Leuthold et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Expression of sulfotransferases and sulfatases in human breast cancer: Impact on resveratrol metabolism

(2009) Michaela Miksits et al.   CANCER LETTERS

Antitumor Activity of Resveratrol and its Sulfated Metabolites against Human Breast Cancer Cells

(2009) Michaela Miksits et al.   PLANTA MEDICA

Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3

(2008) Chunshan Gui et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Quantification of free and protein-boundtrans-resveratrol metabolites and identification oftrans-resveratrol-C/O-conjugated diglucuronides – Two novel resveratrol metabolites in human plasma

(2008) Alexander Burkon et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Intestinal Breast Cancer Resistance Protein (BCRP)/Bcrp1 and Multidrug Resistance Protein 3 (MRP3)/Mrp3 Are Involved in the Pharmacokinetics of Resveratrol

(2008) K. van de Wetering et al.   MOLECULAR PHARMACOLOGY

Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family

(2008) B. Hagenbuch et al.   XENOBIOTICA

Metabolism of resveratrol in breast cancer cell lines: Impact of sulfotransferase 1A1 expression on cell growth inhibition

(2007) Marek Murias et al.   CANCER LETTERS