Dietary flavonoid genistein induces Nrf2 and phase II detoxification gene expression via ERKs and PKC pathways and protects against oxidative stress in Caco-2 cells

Cytoprotective effects of CSTMP, a novel stilbene derivative, against H2O2-induced oxidative stress in human endothelial cells

(2014) Li Zhai et al.   Pharmacological Reports

Genistein cooperates with the histone deacetylase inhibitor vorinostat to induce cell death in prostate cancer cells

(2012) Cornel J Phillip et al.   BMC CANCER

Repression of mammosphere formation of human breast cancer cells by soy isoflavone genistein and blueberry polyphenolic acids suggests diet-mediated targeting of cancer stem-like/progenitor cells

(2012) Maria Theresa E. Montales et al.   CARCINOGENESIS

Flavonoids Protect Cerebrovascular Endothelial Cells through Nrf2 and PI3K from β-Amyloid Peptide-Induced Oxidative Damage

(2012) Yuan-Di Xi et al.   CURRENT NEUROVASCULAR RESEARCH

In vitro models for gluten toxicity: relevance for celiac disease pathogenesis and development of novel treatment options

(2012) Katri Lindfors et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments

(2012) Hongqiao Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genistein Prevents Hyperglycemia-Induced Monocyte Adhesion to Human Aortic Endothelial Cells through Preservation of the cAMP Signaling Pathway and Ameliorates Vascular Inflammation in Obese Diabetic Mice

(2012) Pon Velayutham Anandh Babu et al.   JOURNAL OF NUTRITION

Serum Oxidative Stress-Induced Repression of Nrf2 and GSH Depletion: A Mechanism Potentially Involved in Endothelial Dysfunction of Young Smokers

(2012) Anna Fratta Pasini et al.   PLoS One

The Flavonoid Luteolin Inhibits Fcγ-Dependent Respiratory Burst in Granulocytes, but Not Skin Blistering in a New Model of Pemphigoid in Adult Mice

(2012) Eva Oswald et al.   PLoS One

H2O2 preconditioning modulates phase II enzymes through p38 MAPK and PI3K/Akt activation

(2011) Cristina Angeloni et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The difference of glutathione antioxidant system in newly weaned and young mice liver and its involvement in isoline-induced hepatotoxicity

(2011) Qing-Ning Liang et al.   ARCHIVES OF TOXICOLOGY

Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity

(2011) Wentao Qi et al.   BMC CANCER

Risk factors for breast cancer: epidemiological evidence from Japanese studies

(2011) Motoki Iwasaki et al.   CANCER SCIENCE

Lipoic acid ameliorates arsenic trioxide-induced HO-1 expression and oxidative stress in THP-1 monocytes and macrophages

(2011) Lisu Wang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Induction of glutathione synthesis and heme oxygenase 1 by the flavonoids butein and phloretin is mediated through the ERK/Nrf2 pathway and protects against oxidative stress

(2011) Ya-Chen Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

3′,4′-Didemethylnobiletin induces phase II detoxification gene expression and modulates PI3K/Akt signaling in PC12 cells

(2011) Jeng-Dian Su et al.   FREE RADICAL BIOLOGY AND MEDICINE

Coffees rich in chlorogenic acid or N-methylpyridinium induce chemopreventive phase II-enzymes via the Nrf2/ARE pathway in vitro and in vivo

(2011) Ute Boettler et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Bilberries and their anthocyanins ameliorate experimental colitis

(2011) Heidi Piberger et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Heme oxygenase-1 mediates the protective role of quercetin against ethanol-induced rat hepatocytes oxidative damage

(2011) Shuang Liu et al.   TOXICOLOGY IN VITRO

NF-E2-related factor 2 activation in PC12 cells: its protective role in manganese-induced damage

(2010) Huangyuan Li et al.   ARCHIVES OF TOXICOLOGY

Differentiation- and polarization-dependent zinc tolerance in Caco-2 cells

(2010) Nina Zemann et al.   EUROPEAN JOURNAL OF NUTRITION

Cigarette smoke particle-phase extract induces HO-1 expression in human tracheal smooth muscle cells: role of the c-Src/NADPH oxidase/MAPK/Nrf2 signaling pathway

(2010) Shin-Ei Cheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genistein protects against UVB-induced senescence-like characteristics in human dermal fibroblast by p66Shc down-regulation

(2010) Yi Na Wang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

GM1 Expression in Caco-2 Cells: Characterisation of a Fundamental Passage-dependent Transformation of a Cell Line

(2010) Kristina A. Jahn et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Global Gene Expression Analysis Reveals Differences in Cellular Responses to Hydroxyl- and Superoxide Anion Radical–Induced Oxidative Stress in Caco-2 Cells

(2010) Jacob J. Briedé et al.   TOXICOLOGICAL SCIENCES

Targeting the redox sensitive Nrf2–Keap1 defense pathway in cardiovascular disease: protection afforded by dietary isoflavones

(2009) Giovanni E Mann et al.   CURRENT OPINION IN PHARMACOLOGY

Comparison of Flavonoids and Isoflavonoids as Antioxidants

(2009) Rui-Min Han et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Advanced separation methods of food anthocyanins, isoflavones and flavanols

(2009) Josep Valls et al.   JOURNAL OF CHROMATOGRAPHY A

Kaempferol Suppresses Cisplatin-Induced Apoptosis Via Inductions of Heme Oxygenase-1 and Glutamate-Cysteine Ligase Catalytic Subunit in HEI-OC1 cells

(2009) Shang Shang Gao et al.   PHARMACEUTICAL RESEARCH

Liquiritigenin, a flavonoid aglycone from licorice, has a choleretic effect and the ability to induce hepatic transporters and phase-II enzymes

(2008) Young Woo Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

NF-κB and cancer—identifying targets and mechanisms

(2008) Willscott E Naugler et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT