Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins

Elevated Global DNA Methylation Is Not Exclusive to Amyotrophic Lateral Sclerosis and Is Also Observed in Spinocerebellar Ataxia Types 1 and 2

(2018) Hamid Hamzeiy et al.   Neurodegenerative Diseases

Repetitive element transcripts are elevated in the brain of C9orf72 ALS/FTLD patients

(2017) Mercedes Prudencio et al.   HUMAN MOLECULAR GENETICS

Amyotrophic Lateral Sclerosis

(2017) Robert H. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

Expression of HERV-K108 envelope interferes with HIV-1 production

(2017) Sandra N. Terry et al.   VIROLOGY

A human endogenous retrovirus-derived gene that can contribute to oncogenesis by activating the ERK pathway and inducing migration and invasion

(2017) Cécile Lemaître et al.   PLoS Pathogens

Increase in DNA methylation in patients with amyotrophic lateral sclerosis carriers of not fully penetrant SOD1 mutations

(2017) Fabio Coppedè et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Human Endogenous Retrovirus-K and TDP-43 Expression Bridges ALS and HIV Neuropathology

(2017) Renée N. Douville et al.   Frontiers in Microbiology

HERV-K(HML-2), a seemingly silent subtenant - but still waters run deep

(2016) Kirsten Hanke et al.   APMIS

Human endogenous retroviruses in neurologic disease

(2016) Tove Christensen   APMIS

Infectious Entry Pathway Mediated by the Human Endogenous Retrovirus K Envelope Protein

(2016) Lindsey R. Robinson et al.   JOURNAL OF VIROLOGY

TDP-43 regulates endogenous retrovirus-K viral protein accumulation

(2016) Mamneet Manghera et al.   NEUROBIOLOGY OF DISEASE

A comprehensive approach to expression of L1 loci

(2016) Prescott Deininger et al.   NUCLEIC ACIDS RESEARCH

Discovery of unfixed endogenous retrovirus insertions in diverse human populations

(2016) Julia Halo Wildschutte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells

(2016) Sabine Klawitter et al.   Nature Communications

Activation of HERV-K Env protein is essential for tumorigenesis and metastasis of breast cancer cells

(2016) Fuling Zhou et al.   Oncotarget

Activation of individual L1 retrotransposon instances is restricted to cell-type dependent permissive loci

(2016) Claude Philippe et al.   eLife

Genotype-phenotype correlations of amyotrophic lateral sclerosis

(2016) Hong-Fu Li et al.   Translational Neurodegeneration

Np9, a cellular protein of retroviral ancestry restricted to human, chimpanzee and gorilla, binds and regulates ubiquitin ligase MDM2

(2015) Kristina Heyne et al.   CELL CYCLE

Human Endogenous Retrovirus Type K (HERV-K) Particles Package and Transmit HERV-K–Related Sequences

(2015) Rafael Contreras-Galindo et al.   JOURNAL OF VIROLOGY

Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells

(2015) Edward J. Grow et al.   NATURE

Human endogenous retrovirus HERV-K(HML-2) activity in prostate cancer is dominated by a few loci

(2015) Wolfgang Goering et al.   PROSTATE

Human endogenous retrovirus-K contributes to motor neuron disease

(2015) Wenxue Li et al.   Science Translational Medicine

Differential Expression of HERV-K (HML-2) Proviruses in Cells and Virions of the Teratocarcinoma Cell Line Tera-1

(2015) Neeru Bhardwaj et al.   Viruses-Basel

Expansion of a novel endogenous retrovirus throughout the pericentromeres of modern humans

(2015) Joseph Zahn et al.   GENOME BIOLOGY

HERV-K(HML-2) rec and np9 transcripts not restricted to disease but present in many normal human tissues

(2015) Katja Schmitt et al.   Mobile DNA

The role of TDP-43 in the pathogenesis of ALS and FTLD: Figure 1

(2015) Marco Baralle et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

HIV-1 Interacts with Human Endogenous Retrovirus K (HML-2) Envelopes Derived from Human Primary Lymphocytes

(2014) D. Brinzevich et al.   JOURNAL OF VIROLOGY

Unfixed Endogenous Retroviral Insertions in the Human Population

(2014) E. Marchi et al.   JOURNAL OF VIROLOGY

Retroviruses and amyotrophic lateral sclerosis

(2013) Tariq Alfahad et al.   ANTIVIRAL RESEARCH

Transcriptional Profiling of Human Endogenous Retrovirus Group HERV-K(HML-2) Loci in Melanoma

(2013) Katja Schmitt et al.   Genome Biology and Evolution

HIV infection reveals widespread expansion of novel centromeric human endogenous retroviruses

(2013) R. Contreras-Galindo et al.   GENOME RESEARCH

Comprehensive Analysis of Human Endogenous Retrovirus Group HERV-W Locus Transcription in Multiple Sclerosis Brain Lesions by High-Throughput Amplicon Sequencing

(2013) K. Schmitt et al.   JOURNAL OF VIROLOGY

Staufen-1 Interacts with the Human Endogenous Retrovirus Family HERV-K(HML-2) Rec and Gag Proteins and Increases Virion Production

(2013) K. Hanke et al.   JOURNAL OF VIROLOGY

The viral oncogene Np9 acts as a critical molecular switch for co-activating β-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells

(2013) T Chen et al.   LEUKEMIA

Aberrant Regulation of DNA Methylation in Amyotrophic Lateral Sclerosis: A New Target of Disease Mechanisms

(2013) Lee J. Martin et al.   Neurotherapeutics

Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells

(2013) Nina V Fuchs et al.   Retrovirology

Endogenous retroviruses: acquisition, amplification and taming of genome invaders

(2013) Marie Dewannieux et al.   Current Opinion in Virology

Detection of Human Endogenous Retrovirus K (HERV-K) Transcripts in Human Prostate Cancer Cell Lines

(2013) Lorenzo Agoni et al.   Frontiers in Oncology

The Rec protein of HERV-K(HML-2) upregulates androgen receptor activity by binding to the human small glutamine-rich tetratricopeptide repeat protein (hSGT)

(2012) Kirsten Hanke et al.   INTERNATIONAL JOURNAL OF CANCER

Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

(2012) Elisa Majounie et al.   LANCET NEUROLOGY

Studies of endogenous retroviruses reveal a continuing evolutionary saga

(2012) Jonathan P. Stoye   NATURE REVIEWS MICROBIOLOGY

Characterization of Human Endogenous Retroviral Elements in the Blood of HIV-1-Infected Individuals

(2011) R. Contreras-Galindo et al.   JOURNAL OF VIROLOGY

Identification, characterization, and comparative genomic distribution of the HERV-K (HML-2) group of human endogenous retroviruses

(2011) Ravi P Subramanian et al.   Retrovirology

A revised nomenclature for transcribed human endogenous retroviral loci

(2011) Jens Mayer et al.   Mobile DNA

Identification of active loci of a human endogenous retrovirus in neurons of patients with amyotrophic lateral sclerosis

(2010) Renée Douville et al.   ANNALS OF NEUROLOGY

Human endogenous retrovirus protein Rec interacts with the testicular zinc-finger protein and androgen receptor

(2010) S. Kaufmann et al.   JOURNAL OF GENERAL VIROLOGY

Reconstitution of the Ancestral Glycoprotein of Human Endogenous Retrovirus K and Modulation of Its Functional Activity by Truncation of the Cytoplasmic Domain

(2009) K. Hanke et al.   JOURNAL OF VIROLOGY

Human endogenous retrovirus HERV-K(HML-2) encodes a stable signal peptide with biological properties distinct from Rec

(2009) Alessia Ruggieri et al.   Retrovirology

Effects of Retroviruses on Host Genome Function

(2008) Patric Jern et al.   Annual Review of Genetics

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project

(2008) Aline Flockerzi et al.   BMC GENOMICS

Endogenous retroviruses

(2008) K. Ruprecht et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Quantification of reverse transcriptase in ALS and elimination of a novel retroviral candidate

(2008) A. L. McCormick et al.   NEUROLOGY