Np9, a cellular protein of retroviral ancestry restricted to human, chimpanzee and gorilla, binds and regulates ubiquitin ligase MDM2

HERV-K(HML-2) rec and np9 transcripts not restricted to disease but present in many normal human tissues

(2015) Katja Schmitt et al.   Mobile DNA

Transcriptional repressor NIR interacts with the p53-inhibiting ubiquitin ligase MDM2

(2014) Kristina Heyne et al.   NUCLEIC ACIDS RESEARCH

A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection

(2013) Jorge Zeron-Medina et al.   CELL

Perinatal exposure to low doses of tributyltin chloride reduces sperm count and quality in mice

(2013) Jiliang Si et al.   ENVIRONMENTAL TOXICOLOGY

Transcriptional Profiling of Human Endogenous Retrovirus Group HERV-K(HML-2) Loci in Melanoma

(2013) Katja Schmitt et al.   Genome Biology and Evolution

The viral oncogene Np9 acts as a critical molecular switch for co-activating β-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells

(2013) T Chen et al.   LEUKEMIA

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells

(2013) Nina V Fuchs et al.   Retrovirology

Proteasome Inhibitors: An Expanding Army Attacking a Unique Target

(2012) Alexei F. Kisselev et al.   CHEMISTRY & BIOLOGY

Primates

(2012) Robert D. Martin   CURRENT BIOLOGY

The development of pluripotent stem cells

(2012) Paul J Gokhale et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

From ancestral infectious retroviruses to bona fide cellular genes: Role of the captured syncytins in placentation

(2012) A. Dupressoir et al.   PLACENTA

Microarray-Based Sketches of the HERV Transcriptome Landscape

(2012) Philippe Pérot et al.   PLoS One

The tumor suppressor p53 induces expression of the pregnancy-supporting human chorionic gonadotropin (hCG) CGB7 gene

(2011) Sindy Sohr et al.   CELL CYCLE

The evolution of MDM2 family genes

(2011) Jamil Momand et al.   GENE

A revised nomenclature for transcribed human endogenous retroviral loci

(2011) Jens Mayer et al.   Mobile DNA

Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells

(2010) K Almstrup et al.   BRITISH JOURNAL OF CANCER

The NP9 protein encoded by the human endogenous retrovirus HERV-K(HML-2) negatively regulates gene activation of the Epstein-Barr virus nuclear antigen 2 (EBNA2)

(2010) Henrik Gross et al.   INTERNATIONAL JOURNAL OF CANCER

Human endogenous retrovirus protein Rec interacts with the testicular zinc-finger protein and androgen receptor

(2010) S. Kaufmann et al.   JOURNAL OF GENERAL VIROLOGY

The C terminus of p53 binds the N-terminal domain of MDM2

(2010) Masha V Poyurovsky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

(2010) K. Heyne et al.   NUCLEIC ACIDS RESEARCH

The p53 orchestra: Mdm2 and Mdmx set the tone

(2010) Mark Wade et al.   TRENDS IN CELL BIOLOGY

Signaling to p53: Ribosomal Proteins Find Their Way

(2009) Yanping Zhang et al.   CANCER CELL

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Classification and nomenclature of endogenous retroviral sequences (ERVs)

(2009) Jonas Blomberg et al.   GENE

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project

(2008) Aline Flockerzi et al.   BMC GENOMICS

Endogenous retroviruses

(2008) K. Ruprecht et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Proteasome Is a Molecular Target of Environmental Toxic Organotins

(2008) Guoqing Shi et al.   ENVIRONMENTAL HEALTH PERSPECTIVES